Multivariate logistic regression model for LDUO.

<p>Hosmer-Lemeshow test: 0.530. R Nagelkerke: 0.240.</p><p><i>Abbreviations:</i> liver damage of uncertain origin (LDUO), Odds ratio (OR), confidence interval (CI), human immunodeficiency virus (HIV), body mass index (BMI), Homeostasis model assessment-insulin resistance (HOMA-IR), lamivudine (3TC), efavirenz (EFV), lopinavir (LPV).</p>*<p>The BMI OR shows the risk of developing LDUO per unit increase in BMI.</p

Baseline characteristics of patients with normal and abnormal liver stiffness values.

<p><i>Abbreviations:</i> liver damage of uncertain origin (LDUO), human immunodeficiency virus (HIV), standard deviation (SD), acquired immunodeficiency syndrome (AIDS), injecting drug user (IDU), body mass index (BMI), low-density cholesterol (LDLc), homeostasis model assessment-insulin resistance (HOMA-IR).</p>*<p>HIV viral load was measured by PCR (Cobas TaqMan, Roche Diagnostic Systems Inc., Pleasanton, CA, USA), detection limit set at 20 IU/mL.</p>†<p>Classified on the basis of Center for Disease Control and Prevention (CDC) recommendations (Revised surveillance case definitions for HIV infection among adults, adolescents, and children aged <18 years and for HIV infection and AIDS among children aged 18 months to <13 years- United States, 2008. MMWR 2008; 57 (No RR-10): 1–14).</p>‡<p>Other causes of HIV transmission include: vertical transmission, blood transfusion, transplant and serovascular accident.</p>§<p>Data available for 168 patients.</p

Main characteristics of the study population 1 and the subpopulation where liver stiffness progression was evaluated.

<p>Main characteristics of the study population 1 and the subpopulation where liver stiffness progression was evaluated.</p

Associations with significant liver stiffness progression (Study 2).

<p>Associations with significant liver stiffness progression (Study 2).</p

Liver stiffness progression rate according to <i>PNPLA3</i> rs738409 genotype.

<p>Liver stiffness progression rate according to <i>PNPLA3</i> rs738409 genotype.</p