MR Images through the fetal brain in three orthogonal planes (HASTEbrain sequences), 24 weeks (V1) and 35 weeks (V2).

<p>MR Images through the fetal brain in three orthogonal planes (HASTEbrain sequences), 24 weeks (V1) and 35 weeks (V2).</p

Demographics and the delivery details for all mothers.

*<p>Note that the estimated means and standard deviations for gestation at delivery and birth weight were corrected for fetal sex, maternal education (education was re-coded as an ordinal variable: 0 = 0 GCSEs; 1 = <5 GCSEs; 2 = >5 GCSEs/A-levels/degree), and maternal age as derived from the ANCOVA (IBM SPSS Statistics Version 20, NY, USA).</p

Fetal growth data showing group results at both visits and individual data.

<p>Fetal growth data showing group results at both visits and individual data.</p

Placental growth data showing group results at both visits and individual data.

<p>Placental growth data showing group results at both visits and individual data.</p

Lung growth data showing group results at both visits and individual data.

<p>Lung growth data showing group results at both visits and individual data.</p

The mean and standard error for fetal organ volumes, placenta volume and total fetal volume at Visit 1.

<p>The mean and standard error were corrected for fetal sex, maternal education (education was re-coded as an ordinal variable: 0 = 0 GCSEs; 1 = <5 GCSEs; 2 = >5 GCSEs/A-levels/degree), gestational age at Visit 1 and the difference in gestational age between Visits 1 and 2.</p

Brain growth data showing group results at both visits and individual data.

<p>Brain growth data showing group results at both visits and individual data.</p

The mean and standard error for fetal organ volumes, placenta volume and total fetal volume at Visit 2.

<p>The mean and standard error were corrected for fetal sex, maternal education (education was re-coded as an ordinal variable: 0 = 0 GCSEs; 1 = <5 GCSEs; 2 = >5 GCSEs/A-levels/degree), gestational age at Visit 1 and the difference in gestational age between Visits 1 and 2.</p

The effect of exposure on the volume of fetal organs was assessed using a mixed model ANCOVA.

<p>Each independent analysis included one within-subject variable of visit and one between-subject variable of exposure to maternal cigarette smoking, with four covariates.</p