BEHAVIORAL INTERVENTIONS FOR HIGHER-ORDER RESTRICTED AND REPETITIVE BEHAVIORS IN AUTISM: A SYSTEMATIC REVIEW AND META-ANALYSIS

Although higher-order restricted and repetitive behaviors (H-RRBs) are associated with social, emotional, and behavioral difficulties in individuals with Autism Spectrum Disorder (ASD), there is a paucity of literature on behavioral interventions to treat this core symptom. Through a systematic search, 29 intervention studies that target H-RRBs were identified and analyzed in terms of (a) participant characteristics, (b) setting, (c) targeted behaviors, (d) intervention procedures, (e) experimental design, (f) outcomes and certainty of evidence, and (g) generalization and maintenance of outcomes. Overall, 41% of studies (n=12) yielded large effect sizes, 34% yielded medium effects (n=10), and 17% yielded small effects (n=5). Results suggest that studies yielding large effect sizes were more likely to be rooted in applied behavior analysis (ABA) than cognitive behavioral therapy (CBT), more likely to use function-based than non-function-based interventions, more likely to use both antecedent- and consequence-based interventions versus either one alone, more likely to use single-subject designs than group designs, and were more likely to be classified as focused intervention practices than comprehensive treatment models or manualized treatment programs. Overall, results suggest that ABA and CBT approaches to treating H-RRBs show promise. Directions for future research are discussed

New Orleans Producers: Directing the Regional Food System One Informal Contract at a Time

Large corporations largely control food production and distribution in the global food system and have generated a desire for locally produced food. Although small independent producers still contribute to regional food systems, there is little understanding about how they distribute and market their products. This thesis uses both semistructured interviews to investigate the distribution practices of urban, family, and regional producers in the New Orleans region and discourse analysis to disclose how localist discourse shapes producers marketing practices. The discourse analysis discovered that the web presence of local New Orleans restaurants, farmers, and Crescent City Farmers Market targeted concepts that reflect localist beliefs and values. It was also established that small producers respond to consumer demands, but still have the power to shape the regional food system through negotiating informal contracts and striving to enter into the niche market

New Orleans Producers: Directing the Regional Food System One Informal Contract at a Time

Large corporations largely control food production and distribution in the global food system and have generated a desire for locally produced food. Although small independent producers still contribute to regional food systems, there is little understanding about how they distribute and market their products. This thesis uses both semistructured interviews to investigate the distribution practices of urban, family, and regional producers in the New Orleans region and discourse analysis to disclose how localist discourse shapes producers marketing practices. The discourse analysis discovered that the web presence of local New Orleans restaurants, farmers, and Crescent City Farmers Market targeted concepts that reflect localist beliefs and values. It was also established that small producers respond to consumer demands, but still have the power to shape the regional food system through negotiating informal contracts and striving to enter into the niche market

A Roadmap for Promoting Women's Economic Empowerment

This document summarizes findings of 18 research studies commissioned across 4 categories (entrepreneurship, farming, wage employment, young women's employment) to find out what works to empower women, for whom (categories of women), and where (country scenarios). The Roadmap is designed to guide investments from private sector and public-private partnerships, and highlights 9 proven, 9 promising, and 6 high-potential interventions to increase women's productivity and earnings in developing countries

The Role Of Individual Differences In Bilingual Language Processing

In this thesis, I investigated the neural correlates of bilingualism, and how individual differences in both brain and behaviour affect second language processing. To date, theories of bilingualism have tended to treat bilinguals as a uniform group, while in practice they vary greatly in both experience and ability. By examining how individual differences in proficiency and age of acquisition contribute to second language learning and processing, I sought to address this issue. In chapter two, I used event-related potentials to investigate how age of acquisition and proficiency modulate processing of a novel versus a grammatical rule that is similar across languages. I provided evidence that both age of acquisition and proficiency, in addition to bilingual status, modulate processing of a novel grammatical rule. In contrast, only proficiency predicted processing of a similar grammatical rule. Thus, while the similarities between languages affect second language processing, the degree of their influence is modulated by individual differences in second language experience. In chapter three, I used functional magnetic resonance imaging to investigate how bilinguals represent their shared, integrated lexicons in the brain. Several areas showed differing patterns of representation, while univariate analyses in these areas showed no differences in levels of activation. The separate representation of first and second languages in these regions provides a possible basis for the neurocognitive realization of a shared, integrated lexicon proposed by many theories of bilingualism. In chapter four, I used diffusion tensor imaging to investigate how AoA modulates white matter microstructure, examining white matter tracts in the left and right hemispheres that underlie language processing. Group statistics suggested that second language speakers as a whole may have lower fractional anisotropy, while the within-group analysis revealed that white matter integrity is sensitive to individual experience. Chapter five discusses the relevant findings of the previous chapters, and considers how individual differences arise. Next, I make recommendations for theories of bilingual language processing, and close with a discussion of future research directions

The influence of proficiency and age of acquisition on second language processing: An fMRI study of Mandarin-English bilinguals

Research investigating the neural correlates of second language (L2) processing has usually studied age of acquisition (AoA) and proficiency separately. Presently, we examined both in parallel, treated as continuous variables. We used fMRI to study neural activity for L2 processing in adult native Mandarin speakers who are L2 English speakers. Behavioral measures of language proficiency and AoA were obtained from subjects prior to performing a picture-word matching task during an fMRI scan. Brain activity during L2 English processing was shown to be independently affected by AoA and proficiency; activity in left superior temporal gyrus and right parahippocampal gyrus was modulated by AoA when L2 proficiency is accounted for, while activity in right insula, right middle temporal gyrus, and left parahippocampal gyrus was modulated by L2 proficiency regardless of AoA. These results suggest that brain organization of L2 lexico-semantic processing is susceptible to L2 ability levels as well as age-dependent learning

What Does it Take to Make Discovery a Success?: A Survey of Discovery Tool Adoption, Instruction, and Evaluation Among Academic Libraries

Discovery tools have been widely adopted by academic libraries, yet little information exists that connects common practices regarding discovery tool implementation, maintenance, assessment, and staffing with conventions for research and instruction. The authors surveyed heads of reference and instruction departments in research and land-grant university libraries. The survey results revealed common practices with discovery tools among academic libraries. This study also draws connections between operational, instructional, and assessment practices and perceptions that participants have of the success of their discovery tool. Participants who indicated successful implementation of their discovery tool hailed from institutions that made significant commitments to the operations, maintenance, and acceptance of their discovery tool. Participants who indicated an unsuccessful implementation, or who were unsure about the success of their implementation, did not make lasting commitments to the technical maintenance, operations, and acceptance of their discovery tool

Optimizing Guideline-Recommended Antibiotic Doses for Pediatric Infective Endocarditis

The American Heart Association recently published an updated scientific statement on the management of infective endocarditis in childhood. The recommendations included for vancomycin, aminoglycoside, and β-lactam dosing and monitoring are based primarily on expert opinion and do not consider available evidence for dose optimization based on pharmacokinetic and pharmacodynamic principles in pediatric patients. This is concerning because even when clinically necessary, some practitioners may be hesitant to deviate from guideline-recommended doses. In this perspective, we highlight potential areas for improvement in the statement-recommended doses and summarize evidence supporting antibiotic dosing optimization. The addition of a pediatric clinical pharmacist with expertise in antibiotic dosing to the panel would be beneficial for future updates