58 research outputs found
What Families, Clinicians and Payors Need to Know About Transitional Rehabilitation
When a person sustains a traumatic brain injury (TBI), he and his family are thrust into a health care system that is unfamiliar and difficult to navigate. Too often, patients do not have access to the full continuum of treatment - especially transitional rehabilitation (TR). This article addresses why that is so and ways to change it
The Simons Observatory: Magnetic Shielding Measurements for the Universal Multiplexing Module
The Simons Observatory (SO) includes four telescopes that will measure the
temperature and polarization of the cosmic microwave background using over
60,000 highly sensitive transition-edge bolometers (TES). These multichroic TES
bolometers are read out by a microwave RF SQUID multiplexing system with a
multiplexing factor of 910. Given that both TESes and SQUIDs are susceptible to
magnetic field pickup and that it is hard to predict how they will respond to
such fields, it is important to characterize the magnetic response of these
systems empirically. This information can then be used to limit spurious
signals by informing magnetic shielding designs for the detectors and readout.
This paper focuses on measurements of magnetic pickup with different magnetic
shielding configurations for the SO universal multiplexing module (UMM), which
contains the SQUIDs, associated resonators, and TES bias circuit. The magnetic
pickup of a prototype UMM was tested under three shielding configurations: no
shielding (copper packaging), aluminum packaging for the UMM, and a
tin/lead-plated shield surrounding the entire dilution refrigerator 100 mK cold
stage. The measurements show that the aluminum packaging outperforms the copper
packaging by a shielding factor of 8-10, and adding the tin/lead-plated 1K
shield further increases the relative shielding factor in the aluminum
configuration by 1-2 orders of magnitude.Comment: 7 pages, 4 figure, conference proceedings submitted to the Journal of
Low Temperature Physic
Developing a New Generation of Integrated Micro-Spec Far Infrared Spectrometers for the EXperiment for Cryogenic Large-Aperture Intensity Mapping (EXCLAIM)
The current state of far-infrared astronomy drives the need to develop
compact, sensitive spectrometers for future space and ground-based instruments.
Here we present details of the -Spec spectrometers currently in
development for the far-infrared balloon mission EXCLAIM. The spectrometers are
designed to cover the m range with a resolution of $\rm R\
=\ \lambda / \Delta\lambda\ =\ 512\rm 638\ \mu\rm \mu\rm R = 64\ \muM{=}2{\sim}8\times10^{-19}\rm W/\sqrt{Hz}\rm \mu$-Spec
spectrometers for EXCLAIM.Comment: 9 pages, 5 figures, to appear in the Proceedings of the SPIE
Astronomical Telescopes + Instrumentation (2022
Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines?
<p>Abstract</p> <p>Background</p> <p>To optimize the fluid status of adult patients with severe malaria, World Health Organization (WHO) guidelines recommend the insertion of a central venous catheter (CVC) and a target central venous pressure (CVP) of 0-5 cmH<sub>2</sub>O. However there are few data from clinical trials to support this recommendation.</p> <p>Methods</p> <p>Twenty-eight adult Indian and Bangladeshi patients admitted to the intensive care unit with severe <it>falciparum </it>malaria were enrolled in the study. All patients had a CVC inserted and had regular CVP measurements recorded. The CVP measurements were compared with markers of disease severity, clinical endpoints and volumetric measures derived from transpulmonary thermodilution.</p> <p>Results</p> <p>There was no correlation between the admission CVP and patient outcome (p = 0.67) or disease severity (p = 0.33). There was no correlation between the baseline CVP and the concomitant extravascular lung water (p = 0.62), global end diastolic volume (p = 0.88) or cardiac index (p = 0.44). There was no correlation between the baseline CVP and the likelihood of a patient being fluid responsive (p = 0.37). On the occasions when the CVP was in the WHO target range patients were usually hypovolaemic and often had pulmonary oedema by volumetric measures. Seven of 28 patients suffered a complication of the CVC insertion, although none were fatal.</p> <p>Conclusion</p> <p>The WHO recommendation for the routine insertion of a CVC, and the maintenance of a CVP of 0-5 cmH<sub>2</sub>O in adults with severe malaria, should be reconsidered.</p
Feasibility, safety, acceptability, and yield of office-based, screening transnasal esophagoscopy (with video)
Endoscopic screening for esophageal neoplasia can identify patients eligible for early intervention for pre-cancerous lesions. Unsedated transnasal esophagoscopy may provide an efficient and accurate endoscopic assessment with fewer risks and less cost compared to conventional upper endoscopy
The Simons Observatory Large Aperture Telescope Receiver
The Simons Observatory (SO) Large Aperture Telescope Receiver (LATR) will be
coupled to the Large Aperture Telescope located at an elevation of 5,200 m on
Cerro Toco in Chile. The resulting instrument will produce arcminute-resolution
millimeter-wave maps of half the sky with unprecedented precision. The LATR is
the largest cryogenic millimeter-wave camera built to date with a diameter of
2.4 m and a length of 2.6 m. It cools 1200 kg of material to 4 K and 200 kg to
100 mk, the operating temperature of the bolometric detectors with bands
centered around 27, 39, 93, 145, 225, and 280 GHz. Ultimately, the LATR will
accommodate 13 40 cm diameter optics tubes, each with three detector wafers and
a total of 62,000 detectors. The LATR design must simultaneously maintain the
optical alignment of the system, control stray light, provide cryogenic
isolation, limit thermal gradients, and minimize the time to cool the system
from room temperature to 100 mK. The interplay between these competing factors
poses unique challenges. We discuss the trade studies involved with the design,
the final optimization, the construction, and ultimate performance of the
system
The Simons Observatory microwave SQUID multiplexing detector module design
Advances in cosmic microwave background (CMB) science depend on increasing
the number of sensitive detectors observing the sky. New instruments deploy
large arrays of superconducting transition-edge sensor (TES) bolometers tiled
densely into ever larger focal planes. High multiplexing factors reduce the
thermal loading on the cryogenic receivers and simplify their design. We
present the design of focal-plane modules with an order of magnitude higher
multiplexing factor than has previously been achieved with TES bolometers. We
focus on the novel cold readout component, which employs microwave SQUID
multiplexing (mux). Simons Observatory will use 49 modules containing
60,000 bolometers to make exquisitely sensitive measurements of the CMB. We
validate the focal-plane module design, presenting measurements of the readout
component with and without a prototype detector array of 1728
polarization-sensitive bolometers coupled to feedhorns. The readout component
achieves a yield and a 910 multiplexing factor. The median white noise
of each readout channel is 65 . This impacts the
projected SO mapping speed by , which is less than is assumed in the
sensitivity projections. The results validate the full functionality of the
module. We discuss the measured performance in the context of SO science
requirements, which are exceeded.Comment: Accepted to The Astrophysical Journa
Tracking the X-ray Polarization of the Black Hole Transient Swift J1727.8-1613 during a State Transition
We report on a campaign on the bright black hole X-ray binary Swift
J1727.81613 centered around five observations by the Imaging X-ray
Polarimetry Explorer (IXPE). This is the first time it has been possible to
trace the evolution of the X-ray polarization of a black hole X-ray binary
across a hard to soft state transition. The 2--8 keV polarization degree slowly
decreased from 4\% to 3\% across the five observations, but
remained in the North-South direction throughout. Using the Australia Telescope
Compact Array (ATCA), we measure the intrinsic 7.25 GHz radio polarization to
align in the same direction. Assuming the radio polarization aligns with the
jet direction (which can be tested in the future with resolved jet images),
this implies that the X-ray corona is extended in the disk plane, rather than
along the jet axis, for the entire hard intermediate state. This in turn
implies that the long (10 ms) soft lags that we measure with the
Neutron star Interior Composition ExploreR (NICER) are dominated by processes
other than pure light-crossing delays. Moreover, we find that the evolution of
the soft lag amplitude with spectral state differs from the common trend seen
for other sources, implying that Swift J1727.81613 is a member of a hitherto
under-sampled sub-population.Comment: Submitted to ApJ. 20 pages, 8 figure
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