Quantile-quantile plot of observed against expected heterogeneity P-value for allelic associations with HDL-C.

<p>The grey shaded area represents the 95% confidence interval.</p

Descriptive characteristics of genotyped adolescents and adults stratified by sex.

<p>Descriptive characteristics of genotyped adolescents and adults stratified by sex.</p

Quantile-quantile plot of observed against expected heterogeneity P-value for allelic associations with triglycerides.

<p>The grey shaded area represents the 95% confidence interval.</p

Quantile-quantile plot of observed against expected heterogeneity P-value for allelic associations with LDL-C.

<p>The grey shaded area represents the 95% confidence interval.</p

Loci exhibiting adult-adolescent heterogeneity at p<0.05. The locus/phenotype combinations tested were based on the significant associations reported for adults by Teslovich et al.

<p>“Allele/MAF” listed are: major allele, minor allele frequency (MAF). Numbers in “Beta” columns are in SD units, modelled as additive effect of the reference allele.</p

Number of twins, siblings, parents and spouses and their mean age (standard deviation) and age range.

<p>Number of twins, siblings, parents and spouses and their mean age (standard deviation) and age range.</p

Maximum likelihood parameter estimates and goodness of fit indices from the extended twin design for borderline personality (95% confidence intervals in parentheses for the best fitting model).

<p>Model I: cultural transmission model</p><p>Model II: dominance model; no cultural transmission</p><p>Model III: as model II, no dominance</p><p>Model IV: as model III, no additive genetic effects</p><p>Model V: as model II, no assortment</p><p>Best fitting model printed in bold.</p

Tests of variances, means and correlations.

<p>Note: vs = versus, -2LL = -2 log likelihood, df = degrees of freedom, <i>p</i> = <i>p</i>-value</p><p>The best fitting model is printed in bold.</p

Correlations for BPD features between family members of different degrees of relatedness (number of pairs) and 95% confidence intervals.

<p>The bottom 4 bars collapse across categories above.</p

Participant Mean Age at Assessment, Sex and Zygosity.

<p><i>Note:</i> The age within the final sample ranged from 21 to 49.</p