4,777 research outputs found

    Processing and mechanical properties of cast aluminum containing scandium, zirconium, and ytterbium

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    A series of aluminum alloys containing additions of scandium, zirconium, and ytterbium were cast to evaluate the effect of partial ytterbium substitution for scandium on tensile behavior. Due to the high price of scandium, a crucible-melt interaction study was performed to ensure no scandium was lost in graphite, alumina, magnesia, or zirconia crucibles after holding a liquid Al-Sc master alloy for 8 hours at 900 °C in an argon atmosphere. The alloys were subjected to an isochronal aging treatment and tested for conductivity and Vickers microhardness after each increment. For scandium-containing alloys, peak hardnesses of 520-790 MPa, and peak tensile stresses of 138-234 MPa were observed after aging from 150-350 °C for 3 hours in increments of 50 °C, and for alloys without scandium, peak hardnesses of 217-335 MPa and peak tensile stresses of 45-63 MPa were observed after a 3 hour, 150 °C aging treatment. The hardness and tensile strength of the ytterbium containing alloy was found to be lower than in the alloy with no ytterbium substitution

    A net-present value analysis for a wind turbine purchase at a small US college

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    Wind power is becoming an increasingly attractive method of electric power generation due to concerns with global climate change, increasing uncertainty of future oil supplies, and energy security. While most large-scale wind turbines are part of wind farms, which help states meet state renewable energy standards, several colleges and universities in the United States have purchased wind turbines for financial and educational purposes. This paper gives details of a cost-benefit analysis completed for a small liberal arts college in Illinois, Principia College, which is considering buying a single large-scale turbine. The process set forth here can easily be adapted to any college, university, or school. It is found that the project has a positive net present value for both a 20-year scenario and a 30-year scenario. Assuming the project did not receive any grants, Principia College would need to have an annual real return rate of about 6% on its initial investment to gain the same economic benefits

    Clinical Experience with Radioisotopic Powered Cardiac Pacemakers

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    Significant increase in the useful lifetime of the implantable cardiac pacemaker has been made possible by the development of a radioisotope power source. This paper reports experience with two models, the AEC-ARCO Nu-5 (fixed rate) and the Medtronic Model 9000 (ventricular inhibited demand). Five of the former models were implanted in 1973, and six of the latter more recently. Both types of units have functioned well

    Quantification of the Individual Characteristics of the Human Dentition

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    The considerations for admissibility suggested by the Daubert trilogy challenge forensic experts to provide scientific support for opinion testimony. The defense bar has questioned the reliability of bitemark analysis. Under an award from the U. S. Department of Justice, via the Midwest Forensic Resource Center, a two-year feasibility study was undertaken to quantify six dental characteristics. Using two computer programs, the exemplars of 419 volunteers were digitally scanned, characteristics were measured, and frequency was calculated. The study demonstrates that there were outliers or rare dental characteristics in measurements. An analysis of the intra-observer and inter-observer consistency demonstrated a high degree of agreement. Expansion of the sample size through collaboration with other academic researchers will be necessary to be able to quantify the occurrence of these characteristics in the general population. The automated software application, Tom\u27s Toolbox, developed specifically for this research project, could also provide a template for precisely quantifying other pattern evidence

    High porosity metallic glass foam: A powder metallurgy route

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    A powder metallurgy route to the fabrication of metallic glass foam is introduced. The method involves consolidating metallic glass powder blended with blowing agent particulates to produce expandable precursors, capable of yielding foams with porosities as high as 86%. The foams are found to inherit the strength of the parent metallic glass and to be able to deform heavily toward full densification absorbing high amounts of energy

    Holographic Coulomb Branch Flows with N=1 Supersymmetry

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    We obtain a large, new class of N=1 supersymmetric holographic flow backgrounds with U(1)^3 symmetry. These solutions correspond to flows toward the Coulomb branch of the non-trivial N=1 supersymmetric fixed point. The massless (complex) chiral fields are allowed to develop vevs that are independent of their two phase angles, and this corresponds to allowing the brane to spread with arbitrary, U(1)^2 invariant, radial distributions in each of these directions. Our solutions are "almost Calabi-Yau:" The metric is hermitian with respect to an integrable complex structure, but is not Kahler. The "modulus squared" of the holomorphic (3,0)-form is the volume form, and the complete solution is characterized by a function that must satisfy a single partial differential equation that is closely related to the Calabi-Yau condition. The deformation from a standard Calabi-Yau background is driven by a non-trivial, non-normalizable 3-form flux dual to a fermion mass that reduces the supersymmetry to N=1. This flux also induces dielectric polarization of the D3-branes into D5-branes.Comment: 22 pages; harvmac. Typos corrected;small improvements in presentatio

    Inhibition of Chloroplast DNA Recombination and Repair by Dominant Negative Mutants of \u3ci\u3eEscherichia coli\u3c/i\u3e RecA

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    Escherichia coli RecA, suggest that the plastid recombination system is related to its eubacterial counterpart. Therefore, we examined whether dominant negative mutants of the E. coli RecA protein can interfere with the activity of their putative homolog in the chloroplast of the unicellular green alga Chlamydomonas reinhardtii. Transformants expressing these mutant RecA proteins showed reduced survival rates when exposed to DNA-damaging agents, deficient repair of chloroplast DNA, and diminished plastid DNA recombination. These results strongly support the existence of a RecA-mediated recombination system in chloroplasts. We also found that the wild-type E. coli RecA protein enhances the frequency of plastid DNA recombination over 15-fold, although it has no effect on DNA repair or cell survival. Thus, chloroplast DNA recombination appears to be limited by the availability of enzymes involved in strand exchange rather than by the level of initiating DNA substrates. Our observations suggest that a primary biological role of the recombination system in plastids is in the repair of their DNA, most likely needed to cope with damage due to photooxidation and other environmental stresses. This hypothesis could explain the evolutionary conservation of DNA recombination in chloroplasts despite the predominantly uniparental inheritance of their genomes

    Whole genome sequencing-based mapping and candidate identification of mutations from fixed zebrafish tissue

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    As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology or through transgenic approaches, such as many nervous system defects, has also increased. Screening for these difficult-to-visualize phenotypes demands techniques such as whole-mount in situ hybridization (WISH) or antibody staining, which require tissue fixation. To date, fixed tissue has not been amenable for generating libraries for whole genome sequencing (WGS). Here, we describe a method for using genomic DNA from fixed tissue and a bioinformatics suite for WGS-based mapping of zebrafish mutants. We tested our protocol using two known zebrafish mutant alleles, gpr126st49 and egr2bfh227, both of which cause myelin defects. As further proof of concept we mapped a novel mutation, stl64, identified in a zebrafish WISH screen for myelination defects. We linked stl64 to chromosome 1 and identified a candidate nonsense mutation in the F-box and WD repeat domain containing 7 (fbxw7) gene. Importantly, stl64 mutants phenocopy previously described fbxw7vu56 mutants, and knockdown of fbxw7 in wild-type animals produced similar defects, demonstrating that stl64 disrupts fbxw7. Together, these data show that our mapping protocol can map and identify causative lesions in mutant screens that require tissue fixation for phenotypic analysis

    The Ursinus Weekly, February 24, 1941

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    Kathryn Boghetti gives brilliant performance in contralto recital • Purity of the heart is vespers theme • Hitchler describes wide opportunities in law • Buck Hills conference to be held March 7-9 • Atkinson, Howarth and Scott nominated for May queen contest • Pre-meds to hear talk by Ursinus graduate • G. Adams raised to editorial staff by \u27Weekly\u27 board • Ursinus debaters travel • Women debate \u27plan for union\u27 with Moravian • Beware Joe Louis! Ursinus boxers show great ability for coming intramurals • Co-eds bag 138 braves at Indian motif Lorelei • Byron, Patterson to speak at meeting of IRC Tuesday • Ken Hashagen came to Ursinus via many honors at Penn • A.A.U.W. will consider national defense at Freeland dinner • Gettysburg tosses varsity wrestlers; cubs are pinned by Mercersburg • Varsity court team loses two contests on week-end trip • Freshman quintet loses to Diplomats by 32-30 • Bears wilt in second half: lose to Diplomats, 41-27 • Frosh triumph 48-34 over Norristown YMCAhttps://digitalcommons.ursinus.edu/weekly/1809/thumbnail.jp

    The complex geometry of holographic flows of quiver gauge theories

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    We argue that the complete Klebanov-Witten flow solution must be described by a Calabi-Yau metric on the conifold, interpolating between the orbifold at infinity and the cone over T^(1,1) in the interior. We show that the complete flow solution is characterized completely by a single, simple, quasi-linear, second order PDE, or "master equation," in two variables. We show that the Pilch-Warner flow solution is almost Calabi-Yau: It has a complex structure, a hermitian metric, and a holomorphic (3,0)-form that is a square root of the volume form. It is, however, not Kahler. We discuss the relationship between the master equation derived here for Calabi-Yau geometries and such equations encountered elsewhere and that govern supersymmetric backgrounds with multiple, independent fluxes.Comment: 26 pages, harvmac + amssy
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