First experiences with the Landsat-8 aquatic reflectance product: evaluation of the regional and ocean color algorithms in a coastal environment

Since the launch of the Landsat-8 (L8) Operational Land Imager (OLI) on February 11, 2013, there has been a continuous effort to produce reliable ocean color products by taking the advantages of its medium spatial resolution (30 m) and higher Signal to Noise Ratio (SNR). A Provisional Aquatic Reflectance product for the L8 OLI (L8PAR) has been recently released to the public to explore its potential for ocean color applications. This study used a six-year data record of L8 for development of a regionally tuned algorithm (RTA20) for estimating Chlorophyll-a (Chl-a) concentrations around the complex coastal environment of Hong Kong, and is the first to report the usability of the L8PAR product for coastal areas. Furthermore, this study validated three previously developed algorithms, namely RTA16, RTA17 and RTA19, and two ocean color algorithms (OC2 and OC3) modified for L8 OLI by NASA’s Ocean Color group. Results indicate that the newly released L8PAR product has a high potential for estimating the coastal water Chl-a concentrations with higher detail and higher accuracy than previously. The RTA20 algorithm developed in this study outperformed the previous algorithms (RTA16, RTA17, RTA19, OC2 and OC3), e.g., with lower values for Root Mean Square Error (RMSE; 0.92 mg/m3), bias (−0.26 mg/m3) and mean ratio (1.29). Although inferior to the RTA20, the OC2 algorithm also performed well in terms of Pearson’s correlation coefficient (r; 0.84), slope (6.87) and intercept (−8.44) while for RTA20 the values for r, slope and intercept were 0.96, 0.77 and 0.27, respectively. This preliminary evaluation reveals that the OC2 algorithm can be used as an operational algorithm for L8 Chl-a product generation for global coastal areas while RTA20 can be used as a regional algorithm for the routine monitoring of Chl-a concentrations around the coastal areas of Hong Kong or for coastal areas with similar water quality elsewhere in the world

Evaluation of atmospheric correction methods for low to high resolutions satellite remote sensing data

The objective of atmospheric correction is to retrieve surface reflectance from the top of atmosphere (TOA) reflectance. However, estimating surface reflectance from the TOA reflectance satellite data requires knowledge about the state of the atmosphere (e.g., water vapor and ozone) and the contribution of aerosols to the atmospheric path radiance. Thus, obtaining precise measurements of these parameters, which is very difficult, is crucial for accurate estimation of surface reflectance. The SREM (Simplified and Robust Surface Reflectance Estimation Method) is a physical-based atmospheric correction method based on the Radiative transfer (RT) equations of the second simulation of the Satellite Signal in Solar Spectrum (6SV). Essentially the SREM is a simplified version of 6SV which does not require Aerosol Optical Depth (AOD), aerosol type, water vapor, and ozone. An initial study showed accuracy comparable to the Landsat operational Surface Reflectance Products (SRProd) which is generated through different RT models using AOD, water vapor, and ozone data. To further validate the SREM under varying atmospheric conditions and at different spatial resolutions, an independent Reference Surface Reflectance (SRRef) dataset was generated using the AERONET (Aerosol Robotic Network) measurements as input to the 6SV RT model. The surface reflectances estimated by SREM (SRSREM) and SRProd from Planet Scope (PS, at 3 m spatial resolution), Sentinel-2 AB (S2AB) Multi-spectral Instrument (MSI, at 10 to 60 m spatial resolution), and Landsat-8 (L8) operational Land Imager (OLI, at 30 m spatial resolution) were validated against SRRef. Results showed that SRSREM performed similar to the SRProd of PS, S2AB MSI, and L8 OLI against SRRef. An inferior performance (R of 0.35 and 0.57) of L8 OLI's SRProd in the coastal blue (SB1) and blue (SB2) bands was observed, compared to SREM. The comparison of SRSREM with SRProd reveals the robustness of SREM, without using AOD, water vapor, and ozone data, for estimation of surface reflectance for all RT models tested. For some dates, SRRef and the SRProd under-corrected and produced higher values than the TOA reflectance, even when the atmosphere was clear but this was not the case for SREM. Analysis of surface reflectance estimation in shadowed areas revealed that the SRRef and SRProd had mainly negative values in coastal blue and blue bands for L8 OLI, while no negative SR value was observed for SREM in any band. These results recommend the utilization of SREM for the provision of surface reflectance products across a range of sensor

Spatial analysis of the impact of urban geometry and socio-demographic characteristics on COVID-19, a study in Hong Kong

The World Health Organization considered the widespread of COVID-19 over the world as a pandemic. There is still a lack of understanding of its origin, transmission, and treatment methods. Understanding the influencing factors of the COVID-19 can help mitigate its spread, but little research on the spatial factors has been conducted. Therefore, this study explores the effects of urban geometry and socio-demographic factors on the COVID-19 cases in Hong Kong. For each patient, the places they visited during the incubation period before going to hospital were identified, and matched with corresponding attributes of urban geometry (i.e., building geometry, road network, greenspace) and socio-demographic factors (i.e., demographic, educational, economic, household and housing characteristics) based on the coordinates. The local cases were then compared with the imported cases using the stepwise logistic regression, the logistic regression with case-control of time, and the least absolute shrinkage and selection operator regression to identify factors influencing local disease transmission. Results show that the building geometry, road network and certain socio-economic characteristics are significantly associated with COVID-19 cases. In addition, the results indicate that urban geometry is playing a more important role than the socio-demographic characteristics in affecting the COVID-19 incidences. These findings provide a useful reference to the government and the general public as to the spatial vulnerability of the COVID-19 transmission and to take appropriate preventive measures in high-risk areas

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Assessment of MODIS, OMI, MISR and CALIOP Aerosol Products for Estimating Surface Visual Range: A Mathematical Model for Hong Kong

Estimation of atmospheric visibility (VR) using ground and satellite sensors is ineffective under Hong Kong’s complex atmosphere and climate. Therefore, the relationship between columnar Aerosol Optical Depth (AOD) from four space-borne sensors (OMI, MODIS, MISR and CALIOP) and Bext from two visibility-recording stations was evaluated, to recommend an effective satellite-based method and spatial resolution, for estimation of VR over Hong Kong. Since most column-integrated aerosol particle extinction occurs within a mixing layer height (MLH) of 1–3 km, column-based AOD from satellites is expected to give a good indication of surface-level conditions, especially when MLH is a known input. The AOD from both MODIS and MISR showed high correlations with Bext; therefore, both were subjected to rigorous statistical analysis along with climatic data to simulate visibility. The best estimate of ground visibility was obtained from MODIS AOD combined with surface-level climatic data, and this explained 84% of the variance in VR, with a low distance error of 0.27 km. Results suggest that the water vapor mixing ratio (Q) alone can explain the combined effect of Atmospheric Pressure (P), Temperature (T) and Relative Humidity (RH) on VR, and that the advection term (VT) alone is sufficient to explain the effects of T, WS and WD on dispersion of aerosols, and hence on VR

Potential of texture measurements of two-date dual polarization PALSAR data for the improvement of forest biomass estimation

The recently available space-borne SAR sensor, PALSAR, is more promising than its predecessor JERS-1 for biomass estimation because of its long wavelength (L-band), and its ability to provide data with different polarizations, varying incidence angles and higher spatial resolutions. This research investigates the potential of two-date dual polarization (HH and HV) SAR imagery for biomass estimation using different kinds of texture processing and different combinations of single and dual polarization ratios. The investigation is conducted in a mountainous, sub-tropical study area where biomass levels are far beyond the previously recognized saturation levels for L-band SAR images, and forest is a mixture of native and non-native species and plantations.We analyzed two-date SAR data with four steps of image processing, including raw data processing in various combinations, texture measurement parameters of HH and HV polarizations, texture measurement parameters of HH and HV together (both jointly and as a ratio), and a ratio of two-date texture parameters along with a single and two-date ratio. When the processed images were compared with ground data from 50 plots, the performance from raw data processing was low, with adjusted r 2=0.22, but after all four processing steps, promising model accuracy (adjusted r 2=0.90 and RMSE=28.58t/ha) and validation accuracy (using the Leave-One-Out-Cross-Validation) with adjusted r 2=0.88 and RMSE=35.69t/ha, were achieved from the combination of single- and two-date polarization ratios of texture parameters.The strong performance achieved indicates that L-band dual-polarization (HH and HV) SAR data from PALSAR has great potential for biomass estimation, far beyond the previously reported L-band saturation point for biomass. This result is attributed to the synergy among texture processing and dual polarization on the one hand, which were able to average out random speckle noise, and the use of ratio instead of absolute quantities, due to its well known ability to reduce forest structural and terrain effects. The additional use of two-date SAR data with these processing techniques was able to add complementary information derived from biomass response in both wet and dry seasons. Thus overall, undesirable image noise and terrain effects were reduced

Geostationary Satellite Observation of Precipitable Water Vapor Using an Empirical Orthogonal Function (EOF) based Reconstruction Technique over Eastern China

Water vapor, as one of the most important greenhouse gases, is crucial for both climate and atmospheric studies. Considering the high spatial and temporal variations of water vapor, a timely and accurate retrieval of precipitable water vapor (PWV) is urgently needed, but has long been constrained by data availability. Our study derived the vertically integrated precipitable water vapor over eastern China using Multi-functional Transport Satellite (MTSAT) data, which is in geostationary orbit with high temporal resolution. The missing pixels caused by cloud contamination were reconstructed using an Empirical Orthogonal Function (EOF) decomposition method over both spatial and temporal dimensions. GPS meteorology data were used to validate the retrieval and the reconstructed results. The diurnal variation of PWV over eastern China was analyzed using harmonic analysis, which indicates that the reconstructed PWV data can depict the diurnal cycle of PWV caused by evapotranspiration and local thermal circulation