Household clustering of dengue in Vietnam (CSV)

<p>Data underlying analyses published in Anders et al (2015) 'Households as foci for dengue transmission in highly urban Vietnam' PLoS NTD</p

Exposure to poultry for poultry workers in the 12 months prior to serum sample collection.

<p>*Missing data for 8 poultry workers.</p><p>#Missing data for 2 poultry workers.</p

Exposure to poultry for cullers in the 12 months prior to serum sample collection.

<p>*chicken and/or ducks.</p

Protective measures taken by poultry workers and cullers during live poultry exposure as part of poultry work (poultry farmers) or culling (cullers).

<p>*138/183 poultry farmers and 240/317 cullers were exposed to live poultry during the 6 months prior to sample collection.</p

Summary of study design and enrollment.

<p>Summary of study design and enrollment.</p

Spatial and temporal distribution of cluster investigations.

<p>A: Map of Ho Chi Minh City, with inset showing the spatial distribution of dengue positive clusters (filled circles) and negative clusters (open diamonds) within 7 central districts (district numbers are shown). B: Number of dengue positive and negative cluster investigations, by month of enrollment.</p

Characteristics of index cases.

<p>Characteristics of index cases.</p

Cluster composition and characteristics of cluster participants.

<p>*Denominator for percentages is the number of participants with an enrollment sample collected at Visit 1.</p><p>Cluster composition and characteristics of cluster participants.</p

Clinical characteristics and laboratory values of children on admission, and outcome

†<p>Date of vaccination unless otherwise stated.</p>‡<p>HBV: Hepatitis B virus. Both received Euvax B™; MMR: Measles, Mumps, Rubella. All received Priorix™; varicella: Varilrix^R.</p>§<p>swelling at injection site beyond the expected after routine vaccination.</p>∥<p>Inotropes used were dopamine, dobutamine, noradrenaline.</p>**<p>MRSA: methicillin-resistant <i>Staphylococcus aureus</i>. NA denotes not available, a plus sign positive or present, and a minus sign negative or absent.</p>*<p>Normal ranges are as follows: hemoglobin concentration, 105–135 g/L; leukocyte count, 6 to 17.5·10⁹/L; platelet count, 150 to 400·10⁹/L; alanine aminotransferase (ALT) level, below 37 U/L; aspartate aminotransferase (AST) level, below 40 U/L; creatine phosphokinase (CK) below 200 U/L; serum creatinine concentration, 18–80 µmol/L;</p

Rapidly progressive soft tissue infection after vaccination.

<p>Severe tissue necrosis around vaccination site in Child 4, two days following vaccination with MMR. MRSA was cultured from wound fluid.</p