Using learning games for fourth-grade students to teach Vietnamese lessons and teachers' perspectives on learning games

Students can learn   in   a   meaningful way through the use of educational games. When students apply their skills and information in order to progress through a game, a huge degree of engagement is generated among them in the classroom as a result both their capabilities and their learning   increase. 153 children from primary schools in Vietnam participated in this research. The children were split into two groups: an experimental and a control group. Both groups participated in two sessions of word and sentence practice as well as spelling instruction. According to the findings of the study, the educational outcomes of the students are greatly improved when games are used in their classrooms. In addition, research has shown that some teachers are against the use of games in the classroom since it makes it more difficult to prepare educational materials. Some educators believe that playing educational games is a more effective method of instruction as it allows for greater flexibility during the learning process. This makes a contribution to the theoretical framework that is necessary to guide educators and instructors in the process of improving learning game programs for children in primary schools and other learners

Depth-dose distribution in potatoes with low-energy X-rays

Irradiation is known as a handful measure to inhibit potato sprouting, kill harmful bacteria, and increase preservation. The absorbed dose is one of the essential characteristics of the irradiation process. In this study, the depth-dose distributions in potatoes and polymethyl methacrylate were investigated under low-energy X-ray irradiation by using the Fricke dosimeter and Gafchromic film dosimeter. The dose rates required for the rays to penetrate in polymethyl methacrylate were compared with those in potatoes. Polymethyl methacrylate could be used as a phantom in measuring the depth dose delivered in potatoes. The difference in depth-dose distribution in potatoes between one-sided and double-sided irradiation was also investigated. The calculated dose uniformity ratio values are 5.8 and 1.9 for potatoes irradiating one-sided and double-sided

TÀI NGUYÊN VỊ THẾ VÙNG BỜ KHÁNH HÒA: TIỀM NĂNG VÀ TRIỂN VỌNG

Coastal area in Khanh Hoa Province belongs to Coastal South Central Region, where the Vietnam mainland juts out farthest into the west of the East Sea, and has a special relationship in space with the offshore Spratly islands, the geo-strategic Highlands and economic - political centre of Ho Chi Minh City. This coastal area is close to the sloping and deep continental shelf; possesses the diverse landforms and complex spatial structure with the systems of peninsula, islands, bays, lagoons and river mouths etc. that creates enormous potential for geo-natural position resources, of which highlights are the values of coastal bays and islands. In the geo-economic position resources, Khanh Hoa coastal area has great potential to build the base for exploiting offshore resources, establish large  marine economic zones, and develop the economy of marine services, especially the port - navigation and coastal ecotourism. In the geo-political position resources, this is one of leading sites for defending and protecting the country from sea, and ensuring the sovereignty and national interests in the East Sea including the direct administration of Spratly island district. The detailed investigation and assessment of the position resources in this coastal area will be an important scientific basis for the sea and island development in Khanh Hoa province.Vùng bờ tỉnh Khánh Hòa nằm ở duyên hải Nam Trung Bộ, thuộc phần nhô ra xa  nhất của đất liền Việt Nam ra vùng giữa bờ tây Biển Đông, có quan hệ đặc biệt về không gian với quần đảo xa bờ Trường Sa, vùng địa bàn chiến lược Tây Nguyên và trung tâm kinh tế - chính trị thành phố Hồ Chí Minh. Đây là vùng bờ có thềm lục địa phía ngoài sâu và dốc; hình thể và cấu trúc không gian đa dạng và phức tạp với hệ thống các bán đảo, đảo, vũng vịnh, đầm và cửa sông ... tạo ra tiềm năng to lớn về tài nguyên địa - tự nhiên, mà nổi bật là giá trị của hệ thống các vũng vịnh và đảo ven bờ. Về tài nguyên địa - kinh tế, vùng bờ Khánh Hòa có tiềm năng lớn xây dựng cơ sở hậu cần khai thác tài nguyên biển xa, xây dựng các cơ sở kinh tế biển lớn, phát triển kinh tế dịch vụ biển, đặc biệt là cảng - hàng hải và du lịch sinh thái biển. Về tài nguyên địa - chính trị, đây là một trong những vị trí có vai trò quan trọng trong việc phòng thủ và bảo vệ đất nước từ biển, đảm bảo chủ quyền và lợi ích quốc gia trên Biển Đông, trong đó có việc trực tiếp quản lý huyện đảo Trường Sa. Việc điều tra, đánh giá chi tiết tài nguyên vị thế vùng bờ sẽ là cơ sở khoa học quan trọng để phát triển biển đảo tỉnh Khánh Hòa

PHÁT HIỆN MỘT SỐ THUỐC HẠ GLUCOSE MÁU TRỘN LẪN TRONG CHẾ PHẨM DƯỢC LIỆU BẰNG PHƯƠNG PHÁP SẮC KÝ LỎNG HIỆU NĂNG CAO (HPLC)

Circular No. 10/2021/TT-BYT stipulated that several hypoglycemic drugs, such as metformin hydrochloride, are prohibited from adulterating medicinal herbal preparations. Therefore, this study aims to develop a procedure to detect five hypoglycemic drugs, including metformin hydrochloride, glibenclamide, gliclazide, glimepiride, and glipizide, adulterated in herbal preparations by using the high-performance liquid chromatography (HPLC) method. The chromatographic program includes the methanol:phosphate buffer pH 3 mobile phase 70/30 (v/v), chromatographic column C18 (250 × 4.6 mm, 5 μm), and analysis time of 25 minutes. The procedure has high specificity, accuracy and precision, according to AOAC. We detected six herbal products reacting positively with glibenclamide and one with both metformin hydrochloride and glibenclamide.Thông tư số 10/2021/TT-BYT quy định một số thuốc hạ glucose máu, như metformin hydroclorid, là các chất cấm trộn lẫn trong chế phẩm có nguồn gốc từ dược liệu. Do đó, mục tiêu nghiên cứu này là xây dựng quy trình phát hiện năm loại hoạt chất hạ glucose máu, gồm metformin hydroclorid, glibenclamid, gliclazid, glimepirid và glipizid, trộn lẫn trong chế phẩm có nguồn gốc dược liệu bằng phương pháp sắc ký lỏng hiệu năng cao (HPLC). Chúng tôi đã xây dựng được chương trình sắc ký gồm hệ pha động methanol:đệm phosphat pH 3 với tỷ lệ 30/70 (v/v), cột sắc ký C18 (250 × 4,6 mm, 5 μm), và thời gian phân tích 25 phút. Phương pháp thẩm định có tính đặc hiệu cao, độ đúng, độ lặp lại và độ tái lặp cao, đạt yêu cầu theo AOAC. Chúng tôi đã phát hiện bảy mẫu chế phẩm dược liệu dương tính trong đó sáu mẫu dương tính với glibenclamid và một mẫu dương tính đồng thời với metformin và glibenclamid

Factors Influence on Promotion Mix in E-marketing: Case of Technology Services Enterprise in Vietnam

Purpose: The objective of this study is to clarify factors affecting the promotion mix in E-Marketing, with specific target audience being enterprises operating in the technology service industry in Vietnam.   Theoretical framework: Based on the promotion theory and social exchange theory, this study focuses on the factors that influence on the promotion decision in firms.   Design/Methodology/Approach: This study applies both qualitative and quantitative methods with data collected from a questionnaire survey.   Findings: There are 4 factors respectively Sales Promotion, Advertising, Public Relations and Personal Selling that affect the mixed promotion activities in E-Marketing of technology service enterprises in Vietnam.   Research, practical & social implications: This study propose solutions to improve the promotion activities in the e – marketing of firms in Vietnam.   Originality/Value: This study is one of the early studies that have focused in this field in Vietnam.Propósito: El objetivo de este estudio es aclarar los factores que afectan la combinación de promoción en E-Marketing, con un público objetivo específico que son las empresas que operan en la industria de servicios de tecnología en Vietnam. Marco teórico: Basado en la teoría de la promoción y la teoría del intercambio social, este estudio se centra en los factores que influyen en la decisión de promoción en las empresas. Diseño/metodología/enfoque: este estudio aplica métodos cualitativos y cuantitativos con datos recopilados de una encuesta de cuestionario. Hallazgos: Existen 4 factores, respectivamente, Promoción de Ventas, Publicidad, Relaciones Públicas y Ventas Personales que afectan las actividades mixtas de promoción en E-Marketing de las empresas de servicios de tecnología en Vietnam. Implicaciones de investigación, prácticas y sociales: este estudio propone soluciones para mejorar las actividades de promoción en el marketing electrónico de las empresas en Vietnam. Originalidad/valor: Este estudio es uno de los primeros que se han centrado en este campo en Vietnam.Objetivo: O objetivo deste estudo é esclarecer os fatores que afetam o mix de promoção no E-Marketing, tendo como público-alvo específico as empresas que operam no setor de serviços de tecnologia no Vietnã.. Referencial teórico: Com base na teoria da promoção e na teoria das trocas sociais, este estudo se concentra nos fatores que influenciam a decisão de promoção nas empresas.. Desenho/metodologia/abordagem: Este estudo aplica métodos qualitativos e quantitativos com dados coletados de uma pesquisa por questionário. Resultados: Existem 4 fatores, respectivamente, Promoção de Vendas, Publicidade, Relações Públicas e Vendas Pessoais que afetam as atividades de promoção mista em E-Marketing de empresas de serviços de tecnologia no Vietnã. Pesquisa, implicações práticas e sociais: Este estudo propõe soluções para melhorar as atividades de promoção no e – marketing de empresas no Vietnã. Originalidade/valor: Este estudo é um dos primeiros estudos que se concentraram neste campo no Vietnã. Palavras-chave:  Mix de promoção; E-Marketing; Serviços de tecnologia; Vietn

The epidemiology and aetiology of diarrhoeal disease in infancy in southern Vietnam: a birth cohort study.

OBJECTIVES: Previous studies indicate a high burden of diarrhoeal disease in Vietnamese children, however longitudinal community-based data on burden and aetiology are limited. The findings from a large, prospective cohort study of diarrhoeal disease in infants in southern Vietnam are presented herein. METHODS: Infants were enrolled at birth in urban Ho Chi Minh City and a semi-rural district in southern Vietnam, and followed for 12 months (n=6706). Diarrhoeal illness episodes were identified through clinic-based passive surveillance, hospital admissions, and self-reports. RESULTS: The minimum incidence of diarrhoeal illness in the first year of life was 271/1000 infant-years of observation for the whole cohort. Rotavirus was the most commonly detected pathogen (50% of positive samples), followed by norovirus (24%), Campylobacter (20%), Salmonella (18%), and Shigella (16%). Repeat infections were identified in 9% of infants infected with rotavirus, norovirus, Shigella, or Campylobacter, and 13% of those with Salmonella infections. CONCLUSIONS: The minimum incidence of diarrhoeal disease in infants in both urban and semi-rural settings in southern Vietnam was quantified prospectively. A large proportion of laboratory-diagnosed disease was caused by rotavirus and norovirus. These data highlight the unmet need for a rotavirus vaccine in Vietnam and provide evidence of the previously unrecognized burden of norovirus in infants

Enhanced Adsorption of Methylene Blue by Chemically Modified Materials Derived from Phragmites australis Stems

In this study, the biomass of Phragmites australis was chemically modified using NaOH and subsequently citric acid to produce an effective adsorbent named SA-RPB. The absorbent was characterized using XRD, SEM, BET, and FT-IR methods. The study's findings indicated that the adsorbent existed mainly as cellulose crystals, contained micropores with an average diameter of 15.97 nm, and had a large number of hydroxyl and carboxyl groups on the surface. The adsorption process of SA-RPB was evaluated through the adsorption of methylene blue (MB) dye in aqueous solution. Adsorption kinetics showed that the pseudo-second-order model well described the adsorption process. The adsorption isotherm process satisfactorily fitted with the Langmuir model with the maximum adsorption capacity of 191.49 mg/g at 303 K. These findings show that MB may be efficiently removed from aqueous solutions using the adsorbent made from the raw biomass of Phragmites australis treated with NaOH and then citric acid

Age-time-specific transmission of hand-foot-and-mouth disease enterovirus serotypes in Vietnam: a catalytic model with maternal immunity

Hand, foot and mouth disease (HFMD) is highly prevalent in the Asia Pacific region, particularly in Vietnam. To develop effective interventions and efficient vaccination programs, we inferred the age-time-specific transmission patterns of HFMD serotypes enterovirus A71 (EV-A71), coxsackievirus A6 (CV-A6), coxsackievirus A10 (CV-A10), coxsackievirus A16 (CV-A16) in Ho Chi Minh City, Vietnam from a case data collected during 2013–2018 and a serological survey data collected in 2015 and 2017. We proposed a catalytic model framework with good adaptability to incorporate maternal immunity using various mathematical functions. Our results indicate the high-level transmission of CV-A6 and CV-A10 which is not obvious in the case data, due to the variation of disease severity across serotypes. Our results provide statistical evidence supporting the strong association between severe illness and CV-A6 and EV-A71 infections. The HFMD dynamic pattern presents a cyclical pattern with large outbreaks followed by a decline in subsequent years. Additionally, we identify the age group with highest risk of infection as 1-2 years and emphasise the risk of future outbreaks as over 50% of children aged 6-7 years were estimated to be susceptible to CV-A16 and EV-A71. Our study highlights the importance of multivalent vaccines and active surveillance for different serotypes, supports early vaccination prior to 1 year old, and points out the potential utility for vaccinating children older than 5 years old in Vietnam

Experimental cultivation of Spirulina platensis using My An mineral water, Thua Thien Hue province

Spirulina platensis was experimentally cultivated by semi-continuous method at 20m2 scale pilot to effectively use the available bicarbonate and minerals of the My An mineral water, Phu Vang district, Thua Thien Hue province, and reduce production cost. Analyses of My An water quality showed that this mineral water source was suitable to cultivate Spirulina Platensis after removing H2S. The average algal yield reached to 10gDW/m2.day. The obtained algal biomass contained high nutrient compositions and was a suitable source for functional food (68.32 % protein, 7.32 % lipids containing Omega-3 and Omega-6, and low heavy metal concentration). The obtained results indicated that the My An mineral water source was indeed a suitable water source for producing Spirulina platensis biomass as a functional food

Urinary catecholamine excretion, cardiovascular variability, and outcomes in tetanus

Severe tetanus is characterized by muscle spasm and cardiovascular system disturbance. The pathophysiology of muscle spasm is relatively well understood and involves inhibition of central inhibitory synapses by tetanus toxin. That of cardiovascular disturbance is less clear, but is believed to relate to disinhibition of the autonomic nervous system. The clinical syndrome of autonomic nervous system dysfunction (ANSD) seen in severe tetanus is characterized principally by changes in heart rate and blood pressure which have been linked to increased circulating catecholamines. Previous studies have described varying relationships between catecholamines and signs of ANSD in tetanus, but are limited by confounders and assays used. In this study, we aimed to perform detailed characterization of the relationship between catecholamines (adrenaline and noradrenaline), cardiovascular parameters (heart rate and blood pressure) and clinical outcomes (ANSD, mechanical ventilation required, and length of intensive care unit stay) in adults with tetanus, as well as examine whether intrathecal antitoxin administration affected subsequent catecholamine excretion. Noradrenaline and adrenaline were measured by ELISA from 24-h urine collections taken on day 5 of hospitalization in 272 patients enrolled in a 2 × 2 factorial-blinded randomized controlled trial in a Vietnamese hospital. Catecholamine results measured from 263 patients were available for analysis. After adjustment for potential confounders (i.e., age, sex, intervention treatment, and medications), there were indications of non-linear relationships between urinary catecholamines and heart rate. Adrenaline and noradrenaline were associated with subsequent development of ANSD, and length of ICU stay