Single site laparoscopic right hemicolectomy: an oncological feasible option

<p>Abstract</p> <p>Introduction</p> <p>We present the first 7 cases of single site right hemicolectomy in Asia using the new Single Site Laparoscopy (SSL) access system from Ethicon Endo-surgery.</p> <p>Methods</p> <p>Right hemicolectomy was performed using the new Single Site Laparoscopy (SSL) access system. Patient demographics, operative time, histology and post operative recovery and complications were collected and analysed.</p> <p>Results</p> <p>The median operative time was 90 mins (range 60 - 150 mins) and a median wound size of 2.5 cm (range 2 to 4.5 cm). The median number of lymph nodes harvested was 24 (range 20 to 34 lymph nodes). The median length of proximal margin was 70 mm (range 30 to 145 mm) and that of distal margin was 50 mm (35 to 120 mm). All patients had a median hospital stay of 7 days (range 5 to 11) and there were no significant perioperative complications except for 1 patient who had a minor myocardial event.</p> <p>Conclusion</p> <p>Right hemicolectomy using SSL access system is feasible and safe for oncologic surgery.</p

Numerical simulation of chaotic vibration

Chaotic vibration is a new nonlinear vibration phenomenon where a periodic input to a nonlinear system will lead to a non-periodic output. Extensive simulation of chaotic vibration for a single degree of freedom mechanical system with backlash stiffness nonlinearity will be carried out based on certain excitation range in this project. MATLAB will be used to solve a set of nonlinear equations in time that represents the system by the means of numerical algorithms. Both qualitative and quantitative techniques to detect the existence of chaotic vibration will be studied. However, the focus for this project will be only on the qualitative analysis. Graphical solutions such as time responses, state space trajectories, Poincaré maps, power spectrum and bifurcation diagrams will be used to demonstrate the chaotic nature of the vibration. The time response plots will indicate the behavior of the system with respect to time. The state space trajectories represent the state of the system as a whole while Poincaré maps will aim to show the presence of strange attractors. The power spectrums portray the nature of the system with respect to frequency. Bifurcation diagrams are able to prove the infinite periodic doubling effect that lead to chaos. This simulation seeks to investigate the influence of parameters on the behavior of the system. The parameters used will be the both the excitation amplitude and frequency of the sinusoidal loading force, damping and the initial conditions. At each time, only a set of parameters will be varied.Bachelor of Engineerin

Arterio-Pancreatic Syndrome

Acute pancreatitis is a single-organ disorder that has multi-organ sequelae. As a result, it can have varied presentations. Acute pancreatitis presenting as acute limb ischemia is rare. We present a patient with acute pancreatitis presenting with bilateral lower limb ischemia. The episode of acute pancreatitis resolved but the acute lower limb ischemia precipitated as the pancreatitis progressed, and necessitated bilateral above-knee amputations. We review the literature and discuss the pathogenesis of such a phenomenon

Comparison of turbulence models in near wake of transport plane C-130H fuselage

This paper presents a computational fluid dynamics analysis of the delayed detached eddy simulation–shear-stress transport on a 1:16 scale simplified C-130H fuselage model in flight conditions and with a closed cargo ramp to observe the turbulent-flow structures that evolve behind its empennage region. The results of which are also compared against already existing x-vorticity plots of the delayed detached eddy simulation–Spalart–Allmaras with rotation and curvature correction. With vorticity magnitude of 750 rotations∕s, the delayed detached eddy simulation–shear-stress transport is shown to display a lot more detail in terms of the formation and unsteadiness of the upsweep and detached vortices. The simulations are performed with the finite volume solver Cobalt with up to 64 processors on a high-performance computer.Accepted versio

Molecular Scissoring: Facile 3D to 2D Conversion of Lanthanide Metal Organic Frameworks Via Solvent Exfoliation

Five lanthanide MOFs with <b>pcu</b> topology have been exfoliated into nanoplatelets of two-dimensional structures via sonication in the dimethylacetamide solvent. These nanosheets are fluorescent under two-photon excitation dominated by the ligand, indicating energy upconversion ability

Noninvasive and point-of-care surface-enhanced Raman scattering (SERS)-based breathalyzer for mass screening of coronavirus disease 2019 (COVID-19) under 5 min

Population-wide surveillance of COVID-19 requires tests to be quick and accurate to minimize community transmissions. The detection of breath volatile organic compounds presents a promising option for COVID-19 surveillance but is currently limited by bulky instrumentation and inflexible analysis protocol. Here, we design a hand-held surface-enhanced Raman scattering-based breathalyzer to identify COVID-19 infected individuals in under 5 min, achieving >95% sensitivity and specificity across 501 participants regardless of their displayed symptoms. Our SERS-based breathalyzer harnesses key variations in vibrational fingerprints arising from interactions between breath metabolites and multiple molecular receptors to establish a robust partial least-squares discriminant analysis model for high throughput classifications. Crucially, spectral regions influencing classification show strong corroboration with reported potential COVID-19 breath biomarkers, both through experiment and in silico. Our strategy strives to spur the development of next-generation, noninvasive human breath diagnostic toolkits tailored for mass screening purposes.Agency for Science, Technology and Research (A*STAR)Nanyang Technological UniversityNational Medical Research Council (NMRC)Submitted/Accepted versionThis research is supported by National Medical Research Council, Singapore under COVID-19 Research Fund (MOH-COVID19RF-0007 and MOH-COVID19RF-0012), A*STAR Singapore, AME Individual Research Grant (A20E5c0082) and Max Planck Institute-Nanyang Technological University Joint Lab. S.X.L and L.B.T.N. acknowledge Nanyang Presidential scholarship support from Nanyang Technological University, Singapore