3,125 research outputs found

    Multiplicity fluctuations in heavy-ion collisions using canonical and grand-canonical ensemble

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    We report the higher order cumulants and their ratios for baryon, charge and strangeness multiplicity in canonical and grand-canonical ensembles in ideal thermal model including all the resonances. When the number of conserved quanta is small, an explicit treatment of these conserved charges is required, which leads to a canonical description of the system and the fluctuations are significantly different from the grand canonical ensemble. Cumulant ratios of total charge and net-charge multiplicity as a function of collision energies are also compared in grand canonical ensemble.Comment: 7 pages, 5 Figs, Published versio

    Fast cerebellar reflex circuitry requires synaptic vesicle priming by Munc13-3

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    Munc13-3 is a member of the Munc13 family of synaptic vesicle priming proteins and mainly expressed in cerebellar neurons. Munc13-3 null mutant (Munc13-3(−/−)) mice show decreased synaptic release probability at parallel fiber to Purkinje cell, granule cell to Golgi cell, and granule cell to basket cell synapses and exhibit a motor learning deficit at highest rotarod speeds. Since we detected Munc13-3 immunoreactivity in the dentate gyrus, as reported here for the first time, and current studies indicated a crucial role for the cerebellum in hippocampus-dependent spatial memory, we systematically investigated Munc13-3(−/−) mice versus wild-type littermates of both genders with respect to hippocampus-related cognition and a range of basic behaviors, including tests for anxiety, sensory functions, motor performance and balance, sensorimotor gating, social interaction and competence, and repetitive and compulsive behaviors. Neither basic behavior nor hippocampus-dependent cognitive performance, evaluated by Morris water maze, hole board working and reference memory, IntelliCage-based place learning including multiple reversals, and fear conditioning, showed any difference between genotypes. However, consistent with a disturbed cerebellar reflex circuitry, a reliable reduction in the acoustic startle response in both male and female Munc13-3(−/−) mice was found. To conclude, complete deletion of Munc13-3 leads to a robust decrease in the acoustic startle response. This readout of a fast cerebellar reflex circuitry obviously requires synaptic vesicle priming by Munc13-3 for full functionality, in contrast to other behavioral or cognitive features, where a nearly perfect compensation of Munc13-3 deficiency by related synaptic proteins has to be assumed

    Background measurements and detector response studies for ISMRAN experiment

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    We report the measurement of the non-reactor environmental backgrounds and the detector response with the Indian Scintillator Matrix for Reactor Anti-Neutrinos (ISMRAN), which is ∼\sim1 ton detector setup by volume, consisting of 10×\times9 (10 rows and 9 columns) Plastic Scintillator Bars (PSBs) array at BARC, Mumbai, India. ISMRAN is an above-ground anti-neutrino (ν‾e\mathrm{\overline\nu_{e}}) experiment at very short baseline located at Dhruva research reactor facility. It is enclosed by a shielding made of 10 cm thick lead and 10 cm thick borated polyethylene to minimize the backgrounds and is mounted on a movable base structure, situated at ∼\sim 13 m away from the reactor core. These measurements are useful in the context of the ISMRAN detector setup that will be used to detect the reactor ν‾e\mathrm{\overline\nu_{e}} and measure its energy spectrum through the inverse beta decay (IBD) process. In this paper, we present the energy resolution model and energy non-linearity model of PSB and the cosmogenic muon-induced background, based on the sum of their energy depositions and number of hit bars. Reconstructed sum energy spectrum and number of hit bars distribution for 22Na\mathrm{{}^{22}Na} radioactive source has been compared with Geant4 based Monte Carlo simulations. These experimentally measured results will be useful for discriminating the correlated and uncorrelated background events from the true IBD events in reactor ON and OFF conditions inside the reactor hall.Comment: 4 pages, 4 figures. arXiv admin note: text overlap with arXiv:2208.0349
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