Practical Implementation of Evidence-Based Dentistry Into Daily Dental Practice Through a Short Time Dependent Searching Method

INTRODUCTION:Despite the fact that the benefits of implementation of Evidence-Based Dentistry (EBD) into clinical practice is increasingly being highlighted, there are still clear limitations in its implementation into daily dental practice. One potentially important barrier to effective implementation into practice is the perception of EBD as a time-consuming process. The aim of the present study is to increase the familiarity of dental practitioners with the benefits of different time-dependent 'practical' search strategies important to EBD using a clinical question from the field of dental implantology as an example. MATERIALS AND METHODS:The PICO (population, intervention, comparison, outcome) question used in this study was: "In young adults with anterior single-tooth implant what is the effect of immediate or delayed loading on success?" A bibliographic search according to the Haynes 5S pyramid, together with 3 different time-dependent strategies (5-min, 30-min and more than 60-min), were applied. RESULTS:Both the Haynes 5S Pyramid and time-dependent search strategies revealed promising results for enhancing decision-making for determining the feasibility of immediate or conventional loading of anterior single dental implants. Results clearly showed that selection of the loading protocol would be case (patient)-specific and also indicated high primary implant stability and bone quality as the most important prerequisites for a successful immediate/early loading. From among the 3 different time-dependent strategies (5 min, 30 min and more than 60 min), the 60+ min search results were quite comparable with the Haynes pyramid search results. CONCLUSION:It is likely that the different time-dependent search strategies may have the potential to support the clinical decision making process and may improve the implementation of EBD into daily dental practice. Increased time spent searching naturally seems to increase the extent of this support. However, even with short time-dependent searches, busy dental clinicians may get an improved idea/opinion regarding a clinical question

The effect of Teflubenzuron on the control of Lernanthropas kroyeri (van Beneden, 1851) (Lernanthropidae) infestations in cultured sea bass, Dicentrarchus labrax (Linnaeus, 1758)

Two different dose groups were formed to evaluate the efficacy of teflubenzuron as a treatment for Lernanthropus kroyeri (van Beneden, 1851) infestation in cultured sea bass Dicentrarchus labrax (L.). Teflubenzuron, coated on commercial feed pellets was administered orally at doses of 0 (control), 10, 20 mg kg-1 biomass day-1 for 7 consecutive days. Fish were randomly sampled and parasites were counted on days 7, 14, 21 and 28, and comparisons were made to untreated control fish. Seawater temperature was 16-18 °C. Treatment with teflubenzuron was not effective against larval and mature stages of L. kroyeri. No differences were observed in growth between the treatment groups and the control group. No mortality was found and adverse drug reactions or palatability problems were not associated with the treatments during the study (p > 0,05)

Effect of teflubenzuron on Diplectanum aequans (Monogenea: Diplectanidae) infestations in cultured sea bass, Dicentrarchus labrax

WOS: 000322554300003The efficacy of oral administration of teflubenzuron on cultured sea bass (Dicentarchus labrax) naturally infected with Diplectanum aequans was investigated. Two different groups of fish (sea bass weighing 80-100 g, mean weight: 92 +/- 1 g SD) received a daily dosages of 10 and 20 mg kg-1 teflubenzuron in feed to for 7 days. On day 0, 7, 14,21 and 28 of the experiment, fish were randomly sampled and then parasites on the gills were counted. Comparisons were made to untreated control fish. At experimental start all examined fish were infected with D. aequans. There were no statistical differences (P>0.05) in terms of mean number of D. aequans within each group, including the control. The treatment did not reduce the infection level of D. aequans. No mortality was found and adverse drug reactions or palatability problems were not associated with the treatments during the study. Seawater temperature and salinity in the pens were 16.0-16.5 oC and 35 ppt, respectively

Effect of trichlorfon on Diplectanum aequans (Monogenea: Diplectanidae) infestations in cultured sea bass, Dicentrarchus labrax

WOS: 000305319800004The efficacy of oral administration of trichlorfon on cultured sea bass (Dicentarchus labrax) naturally infected with Diplectanum aequans has been investigated. Sea bass (weighing 80-100 g, mean weight 92 +/- 1 g SD) received a daily dosage of 50 mg kg(-1) trichlorfon in feed to for 7 days. On day 0, 7, 14 and 21 of the experiment, fish were randomly sampled and then parasites on the gills were counted. Comparisons were made to untreated control fish. At the beginning of the experiment all examined fish were infected with D. aequans. There were no statistical differences (P>0.05) in terms of mean number of D. aequans within each group, including the control. During the treatment period, the prevalence decreased in the medicated group by 5 %, 52 %, and 35 % on day 7, 14 and 21, respectively when compared to that of the control group. No mortality was found and adverse drug reactions or palatability problems were not associated with the treatments during the study. The drug may be used during acute outbreaks but due to the risk of anthelmintic resistance this treatment regime cannot be recommended for regular use