714 research outputs found
Applicability of the Fisher Equation to Bacterial Population Dynamics
The applicability of the Fisher equation, which combines diffusion with
logistic nonlinearity, to population dynamics of bacterial colonies is studied
with the help of explicit analytic solutions for the spatial distribution of a
stationary bacterial population under a static mask. The mask protects the
bacteria from ultraviolet light. The solution, which is in terms of Jacobian
elliptic functions, is used to provide a practical prescription to extract
Fisher equation parameters from observations and to decide on the validity of
the Fisher equation.Comment: 5 pages, 3 figs. include
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Advanced Recovery and Integrated Extraction System (ARIES) program plan. Rev. 1
The Advanced Recovery and Integrated Extraction System (ARIES) demonstration combines various technologies, some of which were/are being developed under previous/other Department of Energy (DOE) funded programs. ARIES is an overall processing system for the dismantlement of nuclear weapon primaries. The program will demonstrate dismantlement of nuclear weapons and retrieval of the plutonium into a form that is compatible with long term storage and that is inspectable in an unclassified form appropriate for the application of traditional international safeguards. The success of the ARIES demonstration would lead to the development of a transportable modular or other facility type systems for weapons dismantlement to be used at other DOE sites as well as in other countries
Kosterlitz Thouless Universality in Dimer Models
Using the monomer-dimer representation of strongly coupled U(N) lattice gauge
theories with staggered fermions, we study finite temperature chiral phase
transitions in (2+1) dimensions. A new cluster algorithm allows us to compute
monomer-monomer and dimer-dimer correlations at zero monomer density (chiral
limit) accurately on large lattices. This makes it possible to show
convincingly, for the first time, that these models undergo a finite
temperature phase transition which belongs to the Kosterlitz-Thouless
universality class. We find that this universality class is unaffected even in
the large N limit. This shows that the mean field analysis often used in this
limit breaks down in the critical region.Comment: 4 pages, 4 figure
Non-hermitean delocalization in an array of wells with variable-range widths
Nonhermitean hamiltonians of convection-diffusion type occur in the
description of vortex motion in the presence of a tilted magnetic field as well
as in models of driven population dynamics. We study such hamiltonians in the
case of rectangular barriers of variable size. We determine Lyapunov exponent
and wavenumber of the eigenfunctions within an adiabatic approach, allowing to
reduce the original d=2 phase space to a d=1 attractor. PACS
numbers:05.70.Ln,72.15Rn,74.60.GeComment: 20 pages,10 figure
Test of Replica Theory: Thermodynamics of 2D Model Systems with Quenched Disorder
We study the statistics of thermodynamic quantities in two related systems
with quenched disorder: A (1+1)-dimensional planar lattice of elastic lines in
a random potential and the 2-dimensional random bond dimer model. The first
system is examined by a replica-symmetric Bethe ansatz (RBA) while the latter
is studied numerically by a polynomial algorithm which circumvents slow glassy
dynamics. We establish a mapping of the two models which allows for a detailed
comparison of RBA predictions and simulations. Over a wide range of disorder
strength, the effective lattice stiffness and cumulants of various
thermodynamic quantities in both approaches are found to agree excellently. Our
comparison provides, for the first time, a detailed quantitative confirmation
of the replica approach and renders the planar line lattice a unique testing
ground for concepts in random systems.Comment: 16 pages, 14 figure
Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip
<p>Background—Electrocardiographic traits are important, substantially heritable determinants of risk of arrhythmias and sudden cardiac death.</p>
<p>Methods and Results—In this study, 3 population-based cohorts (n=10 526) genotyped with the Illumina HumanCVD Beadchip and 4 quantitative electrocardiographic traits (PR interval, QRS axis, QRS duration, and QTc interval) were evaluated for single-nucleotide polymorphism associations. Six gene regions contained single nucleotide polymorphisms associated with these traits at P<10−6, including SCN5A (PR interval and QRS duration), CAV1-CAV2 locus (PR interval), CDKN1A (QRS duration), NOS1AP, KCNH2, and KCNQ1 (QTc interval). Expression quantitative trait loci analyses of top associated single-nucleotide polymorphisms were undertaken in human heart and aortic tissues. NOS1AP, SCN5A, IGFBP3, CYP2C9, and CAV1 showed evidence of differential allelic expression. We modeled the effects of ion channel activity on electrocardiographic parameters, estimating the change in gene expression that would account for our observed associations, thus relating epidemiological observations and expression quantitative trait loci data to a systems model of the ECG.</p>
<p>Conclusions—These association results replicate and refine the mapping of previous genome-wide association study findings for electrocardiographic traits, while the expression analysis and modeling approaches offer supporting evidence for a functional role of some of these loci in cardiac excitation/conduction.</p>
Population Dynamics and Non-Hermitian Localization
We review localization with non-Hermitian time evolution as applied to simple
models of population biology with spatially varying growth profiles and
convection. Convection leads to a constant imaginary vector potential in the
Schroedinger-like operator which appears in linearized growth models. We
illustrate the basic ideas by reviewing how convection affects the evolution of
a population influenced by a simple square well growth profile. Results from
discrete lattice growth models in both one and two dimensions are presented. A
set of similarity transformations which lead to exact results for the spectrum
and winding numbers of eigenfunctions for random growth rates in one dimension
is described in detail. We discuss the influence of boundary conditions, and
argue that periodic boundary conditions lead to results which are in fact
typical of a broad class of growth problems with convection.Comment: 19 pages, 11 figure
Adaptation of Autocatalytic Fluctuations to Diffusive Noise
Evolution of a system of diffusing and proliferating mortal reactants is
analyzed in the presence of randomly moving catalysts. While the continuum
description of the problem predicts reactant extinction as the average growth
rate becomes negative, growth rate fluctuations induced by the discrete nature
of the agents are shown to allow for an active phase, where reactants
proliferate as their spatial configuration adapts to the fluctuations of the
catalysts density. The model is explored by employing field theoretical
techniques, numerical simulations and strong coupling analysis. For d<=2, the
system is shown to exhibits an active phase at any growth rate, while for d>2 a
kinetic phase transition is predicted. The applicability of this model as a
prototype for a host of phenomena which exhibit self organization is discussed.Comment: 6 pages 6 figur
Implementation of a Deutsch-like quantum algorithm utilizing entanglement at the two-qubit level, on an NMR quantum information processor
We describe the experimental implementation of a recently proposed quantum
algorithm involving quantum entanglement at the level of two qubits using NMR.
The algorithm solves a generalisation of the Deutsch problem and distinguishes
between even and odd functions using fewer function calls than is possible
classically. The manipulation of entangled states of the two qubits is
essential here, unlike the Deutsch-Jozsa algorithm and the Grover's search
algorithm for two bits.Comment: 4 pages, two eps figure
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