677 research outputs found
The Newsmen\u27s Privilege Against Disclosure of Confidential Sources and Information
When the barrage of subpoenas began in early 1969, statutes of some states recognized an evidentiary privilege of journalists not to reveal confidential sources. In April 1970, the possibility of an additional protective avenue opened when the United States District Court for the Northern District of California granted constitutional protection under the first amendment\u27s freedom of the press clause. By March 1971, this decision had been upheld and extended; the highest courts of three states had ruled upon the claim to constitutional protection with widely divergent results; and at least three petitions had been filed for Supreme Court review of these decisions in the hope that certiorari, uniformly denied in earlier similar cases, now would be granted. This article will examine the decisions since April 1970 and suggest some implications flowing from them, particularly as they bear on the constitutional issues. As a prelude, it will seek to summarize the state of the law on newmen\u27s privilege prior to April 1970
Strangers in the Room: Unpacking Perceptions of 'Smartness' and Related Ethical Concerns in the Home
The increasingly widespread use of 'smart' devices has raised multifarious
ethical concerns regarding their use in domestic spaces. Previous work
examining such ethical dimensions has typically either involved empirical
studies of concerns raised by specific devices and use contexts, or
alternatively expounded on abstract concepts like autonomy, privacy or trust in
relation to 'smart homes' in general. This paper attempts to bridge these
approaches by asking what features of smart devices users consider as rendering
them 'smart' and how these relate to ethical concerns. Through a multimethod
investigation including surveys with smart device users (n=120) and
semi-structured interviews (n=15), we identify and describe eight types of
smartness and explore how they engender a variety of ethical concerns including
privacy, autonomy, and disruption of the social order. We argue that this
middle ground, between concerns arising from particular devices and more
abstract ethical concepts, can better anticipate potential ethical concerns
regarding smart devices.Comment: 10 pages, 1 figure. To appear in the Proceedings of the 2020 ACM
Conference on Designing Interactive Systems (DIS '20
Mitochondrial Dysfunction Accounts for the Stochastic Heterogeneity in Telomere-Dependent Senescence
Aging is an inherently stochastic process, and its hallmark is heterogeneity between organisms, cell types, and clonal populations, even in identical environments. The replicative lifespan of primary human cells is telomere dependent; however, its heterogeneity is not understood. We show that mitochondrial superoxide production increases with replicative age in human fibroblasts despite an adaptive UCP-2–dependent mitochondrial uncoupling. This mitochondrial dysfunction is accompanied by compromised [Ca(2+)](i) homeostasis and other indicators of a retrograde response in senescent cells. Replicative senescence of human fibroblasts is delayed by mild mitochondrial uncoupling. Uncoupling reduces mitochondrial superoxide generation, slows down telomere shortening, and delays formation of telomeric γ-H2A.X foci. This indicates mitochondrial production of reactive oxygen species (ROS) as one of the causes of replicative senescence. By sorting early senescent (SES) cells from young proliferating fibroblast cultures, we show that SES cells have higher ROS levels, dysfunctional mitochondria, shorter telomeres, and telomeric γ-H2A.X foci. We propose that mitochondrial ROS is a major determinant of telomere-dependent senescence at the single-cell level that is responsible for cell-to-cell variation in replicative lifespan
Ly Alpha-Emitting Galaxies at z=3.1: L* Progenitors Experiencing Rapid Star Formation
We studied the clustering properties and multiwavelength spectral energy
distributions of a complete sample of 162 Ly Alpha-Emitting (LAE) galaxies at
z=3.1 discovered in deep narrow-band MUSYC imaging of the Extended Chandra Deep
Field South. LAEs were selected to have observed frame equivalent widths >80A
and emission line fluxes >1.5E-17 erg/cm^2/s. Only 1% of our LAE sample appears
to host AGN. The LAEs exhibit a moderate spatial correlation length of
r_0=3.6+0.8-1.0 Mpc, corresponding to a bias factor b=1.7+0.3-0.4, which
implies median dark matter halo masses of log10(M_med) = 10.9+0.5-0.9 M_sun.
Comparing the number density of LAEs, (1.5+-0.3)E-3/Mpc^3, with the number
density of these halos finds a mean halo occupation ~1-10%. The evolution of
galaxy bias with redshift implies that most z=3.1 LAEs evolve into present-day
galaxies with L3 galaxy populations typically evolve
into more massive galaxies. Halo merger trees show that z=0 descendants occupy
halos with a wide range of masses, with a median descendant mass close to that
of L*. Only 30% of LAEs have sufficient stellar mass (>~3E9 M_sun) to yield
detections in deep Spitzer-IRAC imaging. A two-population SED fit to the
stacked UBVRIzJK+[3.6,4.5,5.6,8.0]micron fluxes of the IRAC-undetected objects
finds that the typical LAE has low stellar mass (1.0+0.6-0.4 E9 M_sun),
moderate star formation rate (2+-1 M_sun/yr), a young component age of 20+30-10
Myr, and little dust (A_V<0.2). The best fit model has 20% of the mass in the
young stellar component, but models without evolved stars are also allowed.Comment: ApJ, in press, 7 pages including 4 color figure
Author Correction: A consensus-based transparency checklist.
An amendment to this paper has been published and can be accessed via a link at the top of the paper
Organizational factors and depression management in community-based primary care settings
Abstract Background Evidence-based quality improvement models for depression have not been fully implemented in routine primary care settings. To date, few studies have examined the organizational factors associated with depression management in real-world primary care practice. To successfully implement quality improvement models for depression, there must be a better understanding of the relevant organizational structure and processes of the primary care setting. The objective of this study is to describe these organizational features of routine primary care practice, and the organization of depression care, using survey questions derived from an evidence-based framework. Methods We used this framework to implement a survey of 27 practices comprised of 49 unique offices within a large primary care practice network in western Pennsylvania. Survey questions addressed practice structure (e.g., human resources, leadership, information technology (IT) infrastructure, and external incentives) and process features (e.g., staff performance, degree of integrated depression care, and IT performance). Results The results of our survey demonstrated substantial variation across the practice network of organizational factors pertinent to implementation of evidence-based depression management. Notably, quality improvement capability and IT infrastructure were widespread, but specific application to depression care differed between practices, as did coordination and communication tasks surrounding depression treatment. Conclusions The primary care practices in the network that we surveyed are at differing stages in their organization and implementation of evidence-based depression management. Practical surveys such as this may serve to better direct implementation of these quality improvement strategies for depression by improving understanding of the organizational barriers and facilitators that exist within both practices and practice networks. In addition, survey information can inform efforts of individual primary care practices in customizing intervention strategies to improve depression management.http://deepblue.lib.umich.edu/bitstream/2027.42/78269/1/1748-5908-4-84.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78269/2/1748-5908-4-84-S1.PDFhttp://deepblue.lib.umich.edu/bitstream/2027.42/78269/3/1748-5908-4-84.pdfPeer Reviewe
- …