Discrete-Time Chaotic-Map Truly Random Number Generators: Design, Implementation, and Variability Analysis of the Zigzag Map

In this paper, we introduce a novel discrete chaotic map named zigzag map that demonstrates excellent chaotic behaviors and can be utilized in Truly Random Number Generators (TRNGs). We comprehensively investigate the map and explore its critical chaotic characteristics and parameters. We further present two circuit implementations for the zigzag map based on the switched current technique as well as the current-mode affine interpolation of the breakpoints. In practice, implementation variations can deteriorate the quality of the output sequence as a result of variation of the chaotic map parameters. In order to quantify the impact of variations on the map performance, we model the variations using a combination of theoretical analysis and Monte-Carlo simulations on the circuits. We demonstrate that even in the presence of the map variations, a TRNG based on the zigzag map passes all of the NIST 800-22 statistical randomness tests using simple post processing of the output data.Comment: To appear in Analog Integrated Circuits and Signal Processing (ALOG

Jackiw-Teitelboim Gravity Generates Horndeski via Disformal Transformations

We show that the most general two-dimensional dilaton gravity theory with second-order field equations, which includes Horndeski and Kinetic Gravity Braiding families, may be obtained from the Jackiw-Teitelboim (JT) gravity through a general disformal transformation, up to boundary terms. We also show that this most general family of theories is closed under generic disformal transformations.Comment: 13 pages, 1 figure

Higher Order and boundary Scaling Fields in the Abelian Sandpile Model

The Abelian Sandpile Model (ASM) is a paradigm of self-organized criticality (SOC) which is related to $c=-2$ conformal field theory. The conformal fields corresponding to some height clusters have been suggested before. Here we derive the first corrections to such fields, in a field theoretical approach, when the lattice parameter is non-vanishing and consider them in the presence of a boundary.Comment: 7 pages, no figure

Sonochemical synthesis of ErVO4/MnWO4 heterostructures: Application as a novel nanostructured surface for electrochemical determination of tyrosine in biological samples

Present strategy introduces a novel method established for the synthesis of spherical shape ErVO4/MnWO4 heterostructures by a sonochemical method. This heterostructures with optima morphology can be synthesized by changing power and time ultrasound irradiation without any capping agent. BET analysis revealed that ErVO4/MnWO4 prepared in the presence of ultrasonic procedure has 75 times specific surface area as much as that of those was produced in the absence of ultrasonic rays. A variety of analyses (i.e., BET, XRD, TEM, EDS, FT-IR, and SEM) were applied for characterization of the ErVO4/MnWO4. Next, a selective and sensitive nanostructured sensor based on ErVO4/MnWO4 nanocomposite modified carbon paste electrode (ErVO4/MnWO4/CPE) was constructed for electrochemical detection of tyrosine (Tyr). The electrochemical characterizations were performed using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and differential pulse voltammetry (DPV). Compared with the unmodified CPE, the oxidation peak current was significantly enhanced for Tyr. The impact of effective parameters on voltammetric response of Tyr was analyzed with design of experiments (DOE) and response surface methodology (RSM). Under the optimized conditions, the oxidation peak current of Tyr was linear over a range of 0.08�400.0 μM with a detection limit of 7.7 nM. Finally, the usage of the proposed method was confirmed by the recovery tests of Tyr in biological samples. © 201

The association of emotional intelligence with sport injuries and receiving penalty cards among Iranian professional soccer players

Background: High emotional intelligence (EI) seems to be preventive for unconventional sports behavior within competitions leading prevention of sport injuries and also minimization of giving penalty cards. Objectives: The present study aimed to examine this relationship among Iranian Premier League footballers. Methods: This study was performed on Iranian professional soccer players participating in Premier League in 2014-2015 season. To assess emotional intelligence among athletes, the Schutte Self-Report Emotional Intelligence test (SSEIT) was employed. Sport-related injuries were recorded by the physician of each team. Also, the reports of the number of yellow and red cards for each athlete as well as for all teams in two phases (middle and end of each season) was recorded by the Football League Organization were reviewed and recorded. The chi-square test and t-test were used for comparing the variables. The Pearson�s correlation test and the multivariable regression model were also used for discovering association and relationship, respectively. P values of 0.05 or less were considered statistically significant. Results: Among different subscales of EI, only regulation of emotions was significantly different between injured and non-injured athletes (P = 0.04). Lower ability to regulate emotions was associated with higher risk for sport injuries (OR = 0.88, 95 CI: 0.79-0.98, P = 0.02). None of the subscales of EI was related to receiving yellow card, but utilizing emotions was adversely related to receiving red card. The association between utilizing emotions and receiving red card changed to insignificant after using the multivariable regression modeling. Conclusions: By regulating emotions, sport-related injuries can be preventable in soccer players. However, EI may not be helpful in reducing sport fines. © 2019, Author(s)

Lipoprotein lipase gene polymorphisms as risk factors for stroke: A computational and meta-analysis

Abstract Objective(s): Stroke is the most common neurological disorder and genetic susceptibility has an important role in its etiology. Polymorphism in several genes such as lipoprotein lipase (LPL) is propounded as a risk for stroke. This meta-analysis investigated the association of rs285 and rs320 LPL polymorphism with stroke risk. Materials and Methods: We searched PubMed, Clarivate Analytics Web of Science, Google Scholar, and Science Direct databases for appropriate studies. The odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to estimate the strength of this association. Also, the effects of four common polymorphisms (rs268, rs285, rs320, and rs328) on the molecular aspects of LPL were evaluated by in silico tools. Five studies were included in meta-analysis after screening. Results: Our data indicated that rs320 significantly decreased the risk of stroke (G vs. T: OR= 0.64, 95%CI=0.54-0.76; GG vs. TT: OR=0.47, 95%CI=0.29-0.75; TG vs. TT: OR=0.65, 95%CI=0.53-0.80; TG+GG vs. TT: OR=0.62, 95%CI=0.51-0.75; GG vs. TT+TG: OR=0.51, 95%CI=0.32-0.82). Moreover, a significant association between rs285 and diminution of stroke risk was seen (P- vs. P+: OR=0.72, 95%CI=0.58-0.91; P-P- vs. P+P+: OR=0.50, 95%CI=0.31-0.82; P+P-+P-P- vs. P+P+: OR=0.72, 95%CI=0.53-0.96; P-P- vs. P+P++P+P-: OR=0.581, 95%CI=0.369-0.916). Also, the same results were observed after stratifying, without any publication bias (PEgger>0.05). Furthermore, computational analysis revealed that rs268 and rs328 may affect the protein structure (prediction: non-neutral; score=19; expected accuracy=59%) while rs320 could affect the RNA structure (distance=0.2264, P-value=0.0534; P<0.2 is significant). Conclusion: This meta-analysis indicated that risk of stroke was decreased in rs320 and rs285 polymorphisms in the LPL gene. Key Words: Computational biology, Genetic polymorphism, Lipoprotein lipase, Meta-analysis, Strok

Neurofilament Light Chain as a Biomarker, and Correlation with Magnetic Resonance Imaging in Diagnosis of CNS-Related Disorders

The search for diagnostic and prognostic biomarkers for neurodegenerative conditions is of high importance, since these disorders may present difficulties in differential diagnosis. Biomarkers with high sensitivity and specificity are required. Neurofilament light chain (NfL) is a unique biomarker related to axonal damage and neural cell death, which is elevated in a number of neurological disorders, and can be detected in cerebrospinal fluid (CSF), as well as blood, serum, or plasma samples. Although the NfL concentration in CSF is higher than that in blood, blood measurement may be easier in practice due to its lesser invasiveness, reproducibility, and convenience. Many studies have investigated NfL in both CSF and serum/plasma as a potential biomarker of neurodegenerative disorders. Neuroimaging biomarkers can also potentially improve detection of CNS-related disorders at an early stage. Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) are sensitive techniques to visualize neuroaxonal loss. Therefore, investigating the combination of NfL levels with indices extracted from MRI and DTI scans could potentially improve diagnosis of CNS-related disorders. This review summarizes the evidence for NfL being a reliable biomarker in the early detection and disease management in several CNS-related disorders. Moreover, we highlight the correlation between MRI and NfL and ask whether they can be combined. © 2019, Springer Science+Business Media, LLC, part of Springer Nature

The bacterial infection of German cockroach (Blatella germanica) in hospitals of western Iran

Cockroaches are considered a serious health problem in some medical centers. They can move freely in hospital wards and transmit pathogenic organisms. This study was carried out in order to detect and identify bacterial infection on outer surface and in digestive organs of Blatella germanica as a dominant species of cockroach in hospitals. In this cross-sectional study 222 B. germanica were collected from 14 different wards and units of 5 hospitals in the city of Hamedan in western Iran. Most of them were collected from dining room (34.2%) followed by urology ward (13.5%). After applying anesthesia and washing in 2cc physiology serum, the culture was prepared from this suspension for identification of bacterial infection on outer surface. Next, the outer surface of each cockroach was sterilized and their guts were isolated from mouth to anus. Bacteria extraction and culture were done accordingly. A total of 12 bacteria species were identified from outer surface and digestive system of cockroaches. On outer surface, Escherichia coli was the most dominant species (40%) followed by Staphylococcus epidermidis (20%). In digestive system E. coli had also the highest percentage (45%) followed by Entrobacter aeroginosa (20%). This study can show the importance of cockroaches as potential vectors of medically important microorganisms such as pathogenic bacteria in hospitals. Control programs for removing cockroaches, especially in the hospitals are recommended