An unusual presentation of vulvar cavernous hemangioma in a 10-year-old premenarchal girl: a rare entity

Vascular tumors of the female genitalia are unusual. Hemangiomas are benign tumors of the blood vessels. Usually they are asymptomatic but may present as discomfort, pain and other symptoms. However, vulvar cavernous hemangioma can be seen in newborns and infants, but rarely occur in children and adult women. A 10-year old premenarchal girl presented with a painless swelling on her right labia majora since birth which was increasing gradually. On examination, a well-defined, soft, mobile and non-tender multicystic swelling was observed involving right labia majora and minora of approximately 5×6 cm in size. An ultrasound of the lesion showed a well-circumscribed, hypo echoic mass with multicystic lesion of size 40×14×44 mm arising from right labia majora with vascularity on color Doppler and venous flow on spectral pattern, suggestive of vascular malformation. Surgical excision of lesion was performed with the utmost care to preserve the surrounding healthy tissue and vulvar anatomy. Histopathological examination (HPE) report confirmed the diagnosis of a cavernous hemangioma with no evidence of malignancy. Vulvar cavernous hemangioma is an uncommon vascular tumor that can be rarely seen in pediatric patients. Imaging studies, such as ultrasound and magnetic resonance imaging (MRI), play a crucial role in confirming the diagnosis and guiding the management. Surgical excision with preservation of healthy tissue is the treatment of choice. Long-term follow-up is essential to monitor recurrence and patient's well-being

Investigating non-Fritzsch like texture specific quark mass matrices

A detailed investigation of all possible textures of Fritzsch-like and non-Fritzsch like, 144 for texture 6 zero and 432 for texture 5 zero mass matrices, have been carried out to ascertain their compatibility with the existing quark mixing data. It seems that all the texture 6 zero possibilities are completely ruled out whereas in the case of texture 5 zero mass matrices the only viable possibility looks to be that of Fritzsch-like.Comment: 13 pages, 4 figures, Accepted for publication in IJMP

Sirenomelia-the mermaid syndrome: a rare invariably fatal congenital anomaly in a term unsupervised pregnancy

Sirenomelia is a rare congenital anomaly with an incidence of 0.8 to 1 case per 1,00,000 births. The prognosis is grim due to associated genitourinary and gastrointestinal anomalies. Antenatal registration in the first trimester and timely ultrasound go a long way in detection of the anamoly when termination can be still be offered and the mental agony of giving birth to a term neonate with a fatal congenital anomaly can be avoided.

Machine Learning Techniques and Testing

In this paper, we have discussed about various algorithms of the machine learning. These algorithms are used in various processes like image automated medical diagnostics, online advertising, robot incomotion etc.   

Exploring the parameter space of texture 4 zero quark mass matrices

We have attempted to extend the parameter space of the elements of the texture 4 zero Hermitian quark mass matrices, to include the case of `weak hierarchy' amongst them along with the usually considered `strong hierarchy' case. This has been carried out by giving wide variation to the hierarchy defining parameters D_U and D_D, having implications for the structural features of the mass matrices. We find that not only the weakly hierarchical mass matrices are able to reproduce the strongly hierarchical mixing angles but also both the phases having their origin in the mass matrices have to be non zero to achieve compatibility of these matrices with recent quark mixing data. Further noting the difference between the exclusive and inclusive values of V_ub, we have carried out separate analyses corresponding to these.Comment: 13 pages, 4 figures, version accepted for publication in Journal Of Physics

Block-chain: The Boon for Bitcoin

The research paper deals with Bitcoin ,its mining and how mining actually works how Bitcoins are made, uses of Bitcoin why we should use Bitco in. Digital wallets for storing Bitcoins It also covers some of the biggest issues associated with Bitcoin like adecentralized currency covering the vast problem of Doublespending ininitial days of Bitcoin trading.The uses of Block-chain in Bit coin’stransaction to solve the problem of Double spending of Bitcoin.Applications of Block-chain other than crypto currency like in healthcare sector,reale state, voting, cyber security,it also covers sections by which we can make block-chain faster especially while buying crypto currencies and why SSDs should be preferred for Bloch-chain operations

Compare the efficacy of chlosite gel as an adjunctive therapy after scaling and root planing

Aim: The present study was carried out to evaluate the clinical efficacy of scaling and root planing (SRP) alone and commercially available chlosite gel adjunctive to SRP in the treatment of chronic periodontitis. Materials and Methods: A total of 416 sites selected from 26 patients presenting with chronic periodontitis (age group ≥30 years) of both sexes, with pocket depth of ≥6 mm were recruited for the study. A split-mouth design was employed with one site receiving SRP alone (Group I) and the other receiving SRP followed by placement of commercially available chlosite gel (Group II) and all the clinical parameters-Plaque index (PI), Gingival index (GI), Probing Pocket depth and Clinical attachment loss (CAL) were recorded at baseline, 1 month, 3 months, and 6 months. Results: Results demonstrated that significant reduction in PI and GI scores were observed in both groups till the end of the study period (6 months). Probing depth and CAL also showed significant improvement in both the groups. However, Group II (sites which received SRP + Chlosite gel) showed greater improvements in all of these parameters compared to Group I (sites which received SRP only). Conclusion: The findings of this study suggest that the locally delivered commercially available chlosite gel along with mechanical debridement, resulted in a clinically meaningful improvement in all the clinical parameters

Scope of photodynamic therapy in periodontics

Periodontal disease results from inflammation of the supporting structure of the teeth and in response to chronic infection caused by various periodontopathic bacteria. The mechanical removal of this biofilm and adjunctive use of antibacterial disinfectants and antibiotics have been the conventional methods of periodontal therapy. However, the removal of plaque and the reduction in the number of infectious organisms can be impaired in sites with difficult access. Photodynamic therapy (PDT) is a powerful laser-initiated photochemical reaction, involving the use of a photoactive dye (photosensitizer) activated by light of a specific wavelength in the presence of oxygen. Application of PDT in periodontics such as pocket debridement, gingivitis, and aggressive periodontitis continue to evolve into a mature clinical treatment modality and is considered as a promising novel approach for eradicating pathogenic bacteria in periodontitis

Clinical evaluation and comparison of human chorion membrane and platelet-rich fibrin with coronally advanced flap in Miller's class I and II recession: A randomized split-mouth clinical trial

Background and Aim: Gingival recession is a malicious and complex phenomenon that needs to be corrected as a patient may complain of hypersensitivity, pain, increased caries risk, and compromised esthetic. Coronally advanced flap (CAF) is a successful technique for its ease of performing and predictable outcome. Guided tissue regeneration membrane such as platelet-rich fibrin (PRF) and human chorion membrane (CM) enhances periodontal regeneration. Hence, this study was conducted to evaluate and compare the efficacy of human CM and PRF with CAF in Miller's class I and II recession defect. Materials and Methods: A total of 14 patients (28 sites) with Miller's class I and II recession defect were assigned and randomly allocated to CM group (Group I) and PRF group (Group II). Clinical parameters recorded were recession depth (RD), recession width (RW), clinical attachment level (CAL), and width of keratinized gingiva (WKG) before surgery. Recession coverage by CAF technique with either CM or PRF was done, and all parameters were again recorded after 1, 3, and 6 months of surgery. Results: Significant decreases were seen from baseline to 6 months' follow-up in both groups regarding RD and RW. WKG was increased in both groups. However, CAL showed statistically significant improvement only in group I and nonsignificant improvement in group II (P = 0.420) at 6 months' follow-up. Conclusion: Both the CM and PRF are effective materials in root coverage, but CM has some amount of better result and long-time stability compared to PRF