Assessment of the Nature of Dyslipoproteinemias and Correlations of Indicators of General Reactivity and Lipid Metabolism in Patients with Chronic Nonspecific Inflammation of the Reproductive System

Metabolic disorders can occur at all levels of biological organization - from molecular and cellular to the level of the organism as a whole. These changes may result from disruptions in hormonal mechanisms, actions of pathogenic factors, or infections. Primary metabolic disorders are the basis of many diseases, such as diabetes, obesity, and atherosclerosis, while secondary disorders accompany most pathological processes. Disruption of lipid metabolism leads to changes in their functions and the development of pathological processes, such as dyslipoproteinemia, and also contributes to the development of atherosclerosis. Various intracellular infectious agents play a significant role in the development of dyslipoproteinemias and atherosclerosis, for example, chlamydia can alter the lipid metabolism in macrophages under the influence of low-density lipoproteins, leading to the formation of 'foam-like' cells. This, in turn, contributes to the development of atheromatous plaques-a favorable environment for chlamydia, where it can survive for an extended period and trigger immunopathological mechanisms

Assessment of the State of Platelet Haemostasis and Adhesive - Aggregation Properties of Platelets as a Factor of Increasing the Tendency to Thrombosis in Chronic Inflammation

In recent decades, considerable progress has been made in understanding the functional mechanisms of platelets and the correction of platelet haemostasis. Platelets are considered the most important participants in both the normal and pathological thrombotic processes characteristic of a variety of diseases and conditions. Alterations in various limbs of haemostasis are found in many somatic diseases (atherosclerosis, coronary heart disease, stroke), surgical procedures, oncological and immunological diseases. Inflammation underlies most diseases and remains an urgent problem in medicine. In the leukocyte infiltration of the inflammatory focus, the mechanism of its self-preservation is of great importance. The activation of haematopoiesis during inflammation is triggered by factors released by stimulated leukocytes of the focus and peripheral blood. Therefore, the problem of the state of the haemostasis system should be the focus of constant attention of clinicians, and with the help of laboratory monitoring of the state of the haemostasis system, it is possible to carry out drug correction of the haemocoagulation potential

Peculiarities of the State of the Body's Immunoprotective Functions, Bacterioscopic and Cytological Studies in the Presence of a Chronic Inflammatory Process of the Reproductive System

At the current stage, the state of health of the Ukrainian nation of reproductive age is characterized by a low birth rate. Chronic inflammatory diseases of the reproductive system significantly affect the health of millions of people of childbearing age. Chronic inflammation is characterized by a protracted, often erased course, a tendency to relapse, the presence of complications and resistance to therapy. The development and formation of inflammatory diseases are based on interconnected processes that begin with acute inflammation and end with destructive changes, therefore the assessment of the body's adaptive capabilities is increasingly considered one of the most important health criteria. There is a whole series of integral hematological indicators that allow you to assess the state of various parts of the immune system without resorting to special research methods

Trends in the development of management and business technology in the formation of the modern Ukrainian economy

The relevance of the research lies in the fact that the formation of an industrial type of society, which is taking place at the current stage, involves a complex of changes in management and the emergence of new tools in the field of economic activity. The purpose of the research is the study of global and domestic directions of further development and analysis of the current state of directions in the outlined area. By the stated goal, the study's task is to systematize Ukraine's challenges and opportunities, which arise as a result of such changes, for representatives of the business community in the managerial aspect. General scientific and special methods of cognition were used to achieve the set goals and tasks of the research. The result of the research substantiation the proposition that the best results from the modernization of management activity can be traced in the production segment. At the current stage, the Ukrainian economy and representatives of the business community will be forced to radically revise their business processes due to changes in the conditions of the internal and external environment, for example, using a special reengineering technique. The introduction of innovations into the usual functionality of the company is connected with the development of market relations, the growth of competition, and open opportunities created based on the rapid improvement of computing machines and devices, as well as information and communication technologies. The conclusion of the study was the substantiation of the position that the decision-making on the reorganization of the management process taking into account the possibilities of digitalization should be made taking into account possible risks for personnel and the current situation on the market, the state of the management system and short-term and long-term development priorities of the enterprise, institution, organization