Satisfaction des parents accompagnateurs des enfants de moins de 5 ans pris en charge au centre médical de Kokologho au Burkina Faso

La satisfaction des usagers des centres médicaux (CM) au Burkina Faso n’est pas connue. Notre objectif était d´étudier le niveau de satisfaction et les facteurs associés des parents accompagnateurs des enfants de moins de 5 ans pris en charge au CM de Kokologho en 2018. Il s’est agi d’une étude transversale. Réalisée dans l’aire de santé du CM de Kokologho, les cibles étaient les parents accompagnateurs d’enfants de moins de 5 ans pour l´enquête ménage et pour les entretiens qualitatifs les représentants de la communauté, les agents de santé et les leaders administratifs et coutumiers. Les outils de collecte des données ont été construits à partir des référentiels (SAPHORA-job 2014, conseil Québécois d’Agrément 2005). Des scores de satisfaction, Odds Ratio ajustées et IC95 % ont été calculés. Des analyses thématiques ont été effectuées. Le niveau de satisfaction globale des parents accompagnateurs des enfants pris en charge au CM de Kokologho en 2018 était satisfaisant (70,6 %). Les dimensions étudiées étaient l’accueil (47,2 %), le respect (65,3 %), l’empathie (60,5 %), la confidentialité (73,8 %), la fiabilité (71,9 %), la rapidité (51,4 %), le confort (89,0 %), l’accessibilité géographique (97,5 %) et l’accessibilité financière (28,5 %). Le niveau d’instruction non scolarisé, le sexe féminin et la situation matrimoniale mariée étaient significativement associés à la satisfaction globale des parents. Les usagers sont satisfaits des services du CM de Kokologho. Cependant, des efforts doivent être faits pour améliorer l’accueil, la rapidité de l’offre de service et l’accessibilité financière.Mots-clés: Satisfaction - parents accompagnateurs - enfants - Burkina FasoEnglish AbstractIntroduction: The satisfaction of users of medical centers in Burkina Faso is not known. Our aim was to study the level of satisfaction and associated factors of the accompanying parents of children under five years taken care in Kokologho medical center in 2018. It was a cross-sectional study. Conducted in the Kokologho medical center health area, the targets were the accompanying parents of children under 5 years for the household survey and for the qualitative interviews community representatives, health workers and administrative and community leaders, customary. The data collection tools were built from the repositories (SAPHORA-job 2014, Conseil Québécois d'Agrément 2005). Satisfaction scores, adjusted Odds Ratio and 95% CI were calculated. Thematic analyzes were carried out. The overall level of satisfaction of the parents of the children in the Kokologho medical center in 2018 was satisfactory at 70.6%. The studied dimensions were patient reception (47.2%), respect (65.3%), empathy (60.5%), confidentiality (73.8%), reliability (71.9%), speed (51.4%), comfort (89.0%), geographical accessibility (97.5%) and affordability (28.5%). Level of education gender and marital status were significantly associated with overall parental satisfaction. Users are satisfied with the services in Kokologho medical center. However, to continue the structural transformation efforts of the district health system, efforts must be made to improve reception, speed of service delivery and affordability.Keywords: satisfaction - accompanying parents - children - Burkina Fas

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

International audienceAbstract Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large clinical trials and accelerated efforts to develop an effective and safe preventative vaccine. Multiple questions regarding the safety, immunogenicity, and efficacy of EVD vaccines remain unanswered. To address these gaps in the evidence base, the Partnership for Research on Ebola Vaccines (PREVAC) trial was designed. This paper describes the design, methods, and baseline results of the PREVAC trial and discusses challenges that led to different protocol amendments. Methods This is a randomized, double-blind, placebo-controlled phase 2 clinical trial of three vaccine strategies against the Ebola virus in healthy volunteers 1 year of age and above. The three vaccine strategies being studied are the rVSVΔG-ZEBOV-GP vaccine, with and without a booster dose at 56 days, and the Ad26.ZEBOV,MVA-FN-Filo vaccine regimen with Ad26.ZEBOV given as the first dose and the MVA-FN-Filo vaccination given 56 days later. There have been 4 versions of the protocol with those enrolled in Version 4.0 comprising the primary analysis cohort. The primary endpoint is based on the antibody titer against the Ebola virus surface glycoprotein measured 12 months following the final injection. Results From April 2017 to December 2018, a total of 5002 volunteers were screened and 4789 enrolled. Participants were enrolled at 6 sites in four countries (Guinea, Liberia, Sierra Leone, and Mali). Of the 4789 participants, 2560 (53%) were adults and 2229 (47%) were children. Those < 18 years of age included 549 (12%) aged 1 to 4 years, 750 (16%) 5 to 11 years, and 930 (19%) aged 12–17 years. At baseline, the median (25th, 75th percentile) antibody titer to Ebola virus glycoprotein for 1090 participants was 72 (50, 116) EU/mL. Discussion The PREVAC trial is evaluating—placebo-controlled—two promising Ebola candidate vaccines in advanced stages of development. The results will address unanswered questions related to short- and long-term safety and immunogenicity for three vaccine strategies in adults and children. Trial registration ClinicalTrials.gov NCT02876328 . Registered on 23 August 2016