Acne-Associated Syndromes

Introduction: Acne, a chronic inflammatory disorder of pilosebaceous unit, is characterized by comedones, pustules, papules, nodules, cysts, and scars. It affects nearly 85% of adolescents. High sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propionibacterium acnes colonization, and inflammation are major pathogenic factors. Systemic disease or syndromes that are associated with acne are less commonly defined. Therefore, these syndromes may not be usually recognized easily

The number of dysplastic and common nevi in patients with malignant melan

Background: There is no data about melanocytic lesions in Turkish patients with melanoma. We aimed to investigate number of melanocytic nevi in melanoma patients compared with control subjects. Methods: We performed a retrospective study in 78 melanoma patients and 78 control subjects. Clinical data were recorded for all participants. Results: As compared with control subjects, patients had more common nevi than control subjects on the legs. The patients and control subjects had similar number of overall and dysplastic nevi. Conclusions: Furthermore, the number of nevi is not a risk factor for our patients, and patients with few or no moles may develop MM, all patients need attentio

Successful treatment of Melkersson-Rosenthal syndrome with dapsone: a case report and review of the literature

Melkersson-Rosenthal syndrome (MRS) is a rare disease characterized by a triad of relapsing or persistent orofacial edema, recurrent lower motor neuron facial nerve palsy and fissured tongue. Acute, painless, non-erythematosus orofacial edema is observed in all patients. We report a case of a 13-year-old girl who presented with a 2-year history of swelling of the upper lip, facial paralysis, and fissured tongue; she was treated successfully with dapsone

Gabapentin-induced aquagenic wrinkling of the palms

Aquagenic keratoderma (AK) or aquagenic wrinklingis a rare palmoplantar skin disease. It is sporadic orhereditary condition. It appears in childhood or youngadulthood and it is seen as multiple asymptomaticsmall shiny papules on the peripheral margin ofpalms and/or soles after submersion in water. Thepathogenesis and etiology of ASA remains unclear.Drugs sometimes trigger AK. Herein, we present thecase of a 29-year-old man who had begun treatmentwith gabapentin three weeks before the onset of hiscutaneous symptoms

Malignant melanoma arising in congenital melanocytic nevi: clinical and dermoscopic challenges

Congenital melanocytic nevi (CMN) are visible pigmented lesions in the skin that are present at birth. CMN are benign malformations resulting from defective development of melanocyte precursors in the embryo. Six MMs from six patients were analyzed by clinical and dermoscopic examination. Of the patients, 33.3% were female (N = 2) and 66.6% were male (N = 4). Of the MMs, four (66.6%) were superficial spreading MM and two (33.3 %) were in situ MM. A reticular pattern was present in the MMs of three patients (50%), a homogeneous pattern was present in the other patients (50%) at the base of the MMs. Superficial spreading melanomas and in situ melanomas with atypical dots and globules and a blue-white veil were the most common dermoscopic features of MMs found in CMN