Why the Water Bridge does not collapse

In 2007 an interesting phenomenon was discovered: a thread of water, the so-called water bridge (WB), can hang between two glass beakers filled with deionized water if voltage is applied to them. We analyze the available explanations of the WB stability and propose a completely different one: the force that supports the WB is the surface tension of water and the role of electric field is not to allow the WB to reduce its surface energy by means of breaking into separate drops.Comment: 4 pages, 3 figure

Role of Oral Lesions in Diagnosing Generalised Recessive Dystrophic Epidermolysis Bullosa- A Rare Case Report

Epidermolysis bullosa (EB) is a heterogeneous group of genetically determined, vesiculo-bullous disorders char­acterized by blister formation in response to mechanical trauma. Three major subgroups, simplex, junctional, and dystrophic EB, contain more than 20 genetically and clini­cally distinct subtypes. In the present case, we described a patient diagnosed with a milder variant of generalised recessive dystrophic epidermolysis bullosa with specific oral and cutaneous lesions, which was previously named as non-Hallopeau-Siemans subtype

Tissue Engineering in Periodontics – A Review

Tissue engineering is a highly promising field of reconstructive biology that draws on recent advances in medicine, surgery, molecular and cellular biology, polymer chemistry, and physiology. The objective of using tissue engineering as therapeutic application has been to harness its ability to exploit selected and primed cells together with an appropriate mix of regulatory factors to allow growth and specialization of cells and matrix. The authors reviewed controlled clinical trials which also included histological studies that evaluated the potential of tissue engineering as a clinical tool in regeneration. PubMed/MEDLINE databases were searched for studies up to and including June 2010 to identify appropriate articles. A comprehensive search was designed, and the articles were independently screened for eligibility. Articles with authentic controls and proper randomization and pertaining specifically to their role in periodontal regeneration were included. Studies demonstrated that periodontal regeneration with the use of combination of tissue engineered products with an osteoconductive matrix improve the beneficial effect of these materials by accelerating cellular in-growth and revascularization of the wound site. Studies have suggested the use of Platelet-derived growth factor alongwith beta tricalcium phosphate for regeneration of the periodontal attachment apparatus in combination with collagen membranes as an acceptable alternative to connective tissue graft for covering gingival recession defects. These studies concluded that growth factors promote true regeneration of the periodontal attachment apparatus and the use of combination protein therapeutics could provide more predictable, faster, and less invasive, less traumatic and efficient outcome for the patients

Pulmonary tumor thrombotic microangiopathy: a systematic review.

Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal disease process in which pulmonary hypertension (PH) develops in the setting of malignancy. The purpose of this study is to present a detailed analysis of cases of PTTM reported in literature in the hopes of achieving more ante-mortem diagnoses. We conducted a systematic review of currently published and available cases of PTTM by searching the term "pulmonary tumor thrombotic microangiopathy" on the Pubmed.gov database. Seventy-nine publications were included consisting of 160 unique cases of PTTM. The most commonly reported malignancy was gastric adenocarcinoma (94 cases, 59%). Cough and dyspnea were reported in 61 (85%) and 102 (94%) cases, respectively. Hypoxemia was reported in 96 cases (95%). Elevation in D-dimer was noted in 36 cases (95%), presence of anemia in 32 cases (84%), and thrombocytopenia in 30 cases (77%). Common findings on chest computed tomography (CT) included ground-glass opacities (GGO) in 28 cases (82%) and nodules in 24 cases (86%). PH on echocardiography was noted in 59 cases (89%) with an average right ventricular systolic pressure of 71 mmHg. Common features of PTTM that are reported across the published literature include presence of dyspnea and cough, hypoxemia, with abnormal CT findings of GGO, nodules, and mediastinal/hilar lymphadenopathy, and PH. PTTM is a universally fatal disease process and this analysis provides a detailed examination of all the available published data that may help clinicians establish an earlier diagnosis of PTTM

Low Temperature Effects during Seed Filling on Chickpea Genotypes (Cicer arietinum L.): Probing Mechanisms affecting Seed Reserves and Yield

Chickpea is sensitive to cold conditions (<15 °C), particularly at its reproductive phase and consequently it experiences significant decrease in the seed yield. The information about the effects of cold stress on chickpea during the seed filling phase is lacking. Moreover, the underlying metabolic reasons associated with the low temperature injury are largely unknown in the crop. Hence, the present study was undertaken with the objectives: (i) to find out the possible mechanisms leading to low temperature damage during the seed filling and (ii) to investigate the relative response of the microcarpa (Desi) and the macrocarpa (Kabuli) chickpea types along with elucidation of the possible mechanisms governing the differential cold sensitivity at this stage. At the time of initiation of the seed filling (pod size ∼1 cm), a set of plants growing under warm conditions of the glasshouse (temperature: 17/28 ± 2 °C as average night and day temperature) was subjected to cold conditions of the field (2.3/11.7 ± 2 °C as average night and day temperature), while another set was maintained under warm conditions (control). The chilling conditions resulted in the increase in electrolyte leakage, the loss of chlorophyll, the decrease in sucrose content and the reduction in water status in leaves, which occurred to a greater extent in the macrocarpa type than in the microcarpa type. The total plant weight decreased to the same level in both the chickpea types, whereas the rate and duration of the seed filling, seed size, seed weight, pods per plant and harvest index decreased greatly in the macrocarpa type. The stressed seeds of both the chickpea types experienced marked reduction in the accumulation of starch, proteins, fats, crude fibre, protein fractions (albumins, globulins, prolamins and glutelins) with a larger decrease in the macrocarpa type. The accumulation of sucrose and the activity levels of the enzymes like starch synthase, sucrose synthase and invertase decreased significantly in the seeds because of the chilling, indicating impairment in sucrose import. Minerals such as calcium, phosphorous and iron as well as several amino acids (phenylalanine, tyrosine, threonine, tryptophan, valine and histidine) were lowered significantly in the stressed seeds. These components were limited to a higher extent in the macrocarpa type indicating higher cold sensitivity of this type

Differential sensitivity of Desi (small-seeded) and Kabuli (large-seeded) chickpea genotypes to water stress during seed filling: effects on accumulation of seed reserves and yield

Water stress during the reproductive phase, especially during seed development, is considered detrimental for chickpea yield. In the present study, the relative sensitivity of Desi and Kabuli chickpea types to water stress during seed filling was assessed in terms of effects on quantitative and qualitative aspects of seed yield. Leaves of both types experienced stress injury (evaluated as electrolyte leakage) to the same extent and possessed almost similar values of water potential at the end of 14 days of water stress. The stressed plants of Kabuli type lost more chlorophyll and had less photosynthesis than Desi type. At maturity, Desi type showed more diminution of vegetative dry matter due to stress over control than Kabuli type. On the other hand, Kabuli type showed a proportionally greater reduction in seed weight per plant, average seed weight, average seed size, number of pods (single- and double-seeded) and harvest index. The stressed seeds of Kabuli type showed 48 and 46% reduction over control in starch and protein content compared with 25 and 40%, respectively in Desi type. The accumulation of soluble sugars was relatively greater due to stress in Kabuli (47%) than Desi type (23%). Fat and fiber content declined by 39 and 35% over control in Desi seeds because of stress whereas Kabuli type showed 46 and 67% decreases, respectively. Protein fractions, namely albumins, globulins, glutelins and prolamins, decreased in stressed seeds of Kabuli by 32, 40, 16 and 15% over control relative to 40, 48, 30 and 28%, respectively, in Kabuli type. The activities of sucrose synthase, invertase and soluble starch synthase were inhibited to a higher extent in Kabuli seeds than Desi seeds under stress. Kabuli seeds showed significantly more reduction in the accumulation of amino acids such as phenylalanine + tyrosine, tryptophan, valine, alanine and histidine and minerals (Ca, P, Fe) due to stress compared with Desi type. Copyright © 2006 Society of Chemical Industr

Exotic bulk viscosity and its influence on neutron star r-modes

We investigate the effect of exotic matter in particular, hyperon matter on neutron star properties such as equation of state (EoS), mass-radius relationship and bulk viscosity. Here we construct equations of state within the framework of a relativistic field theoretical model. As hyperons are produced abundantly in dense matter, hyperon-hyperon interaction becomes important and is included in this model. Hyperon-hyperon interaction gives rise to a softer EoS which results in a smaller maximum mass neutron star compared with the case without the interaction. Next we compute the coefficient of bulk viscosity and the corresponding damping time scale due to the non-leptonic weak process including $\Lambda$ hyperons. Further, we investigate the role of the bulk viscosity on gravitational radiation driven r-mode instability in a neutron star of given mass and temperature and find that the instability is effectively suppressed.Comment: 5 pages, 3 figure, presented in the Conference on Isolated Neutron Stars: From the Interior to The Surface, London, UK, 24-28 April, 2006; revised and final version to appear in Astrophys. Space Sc

Chilling stress effects on reproductive biology of chickpea

Chickpea is sensitive to chilling temperatures (<10°C), especially at its reproductive phase leading to floral abortion. The exact causes of reproductive failures are not fully understood. In the present study, we assessed the cold-induced damage to development and functioning of male and female components by growing an early flowering chickpea genotype ICCV 96029 under warm conditions of the glasshouse (control; average maximum and minimum temperature ≥28/15°C) as well as under cold conditions of the field (average maximum and minimum temperature ≤20/10°C during reproductive phase). Low temperature of the field environment restricted the vegetative growth and delayed all the phenological stages in comparison to control plants. Apart from this, it led to some vegetative aberrations like chlorosis, necrosis of leaf tips and curling of whole leaf. The damage to reproductive stage involved abscission of juvenile buds and flowers and abortion of pods. On the whole, pollen development at young microspore stage appeared to be severely affected in stressed conditions compared to the control conditions. Pollen viability was suppressed during stressed conditions (60%) compared to normal plants (95%). Stigma receptivity, in vivo pollen germination and pollen tube growth were inhibited in the stressed plants. Fluorescent studies showed that the stigma either did not show any pollen load or pollen grains did not germinate on its surface in stressed plants. Even when the pollen grains germinated, the pollen tubes rarely grew beyond the proximal region of the style; mostly the pollen tubes were impaired in their growth and did not reach the ovules leading to failure in fertilization. The egg and secondary nucleus in such ovules ultimately disintegrated without fertilizing and hence no seed formation occurred

Differential Sensitivity of Macrocarpa and Microcarpa Types of Chickpea (Cicer arietinum L.) to Water Stress: Association of Contrasting Stress Response with Oxidative Injury

Chickpea (Cicer arietinum L.) is particularly sensitive to water stress at its reproductive phase and, under conditions of water stress, will abort flowers and pods, thus reducing yield potential. There are two types of chickpea: (i) Macrocarpa (“Kabuli”), which has large, rams head-shaped, light brown seeds; and (ii) Microcarpa (“Desi”), which has small, angular and dark-brown seeds. Relatively speaking, “Kabuli” has been reported to be more sensitive to water stress than “Desi”. The underlying mechanisms associated with contrasting sensitivity to water stress at the metabolic level are not well understood. We hypothesized that one of the reasons for contrasting water stress sensitivity in the two types of chickpea may be a variation in oxidative injury. In the present study, plants of both types were water stressed at the reproductive stage for 14 d. As a result of the stress, the “Kabuli” type exhibited an 80% reduction in seed yield over control compared with a 64% reduction observed for the “Desi” type. The decrease in leaf water potential (Ψw) was faster in the “Kabuli” compared with the “Desi” type. At the end of the water stress period, Ψw was reduced to −2.9 and −3.1 MPa in the “Desi” and “Kabuli” types, respectively, without any significant difference between them. On the last day of stress, “Kabuli” experienced 20% more membrane injury than “Desi”. The chlorophyll content and photosynthetic rate were significantly greater in “Desi” compared with “Kabuli”. The malondialdehyde and H2O2 content were markedly higher at the end of the water stress in “Kabuli” compared with “Desi”, indicating greater oxidative stress in the former. Levels of anti-oxidants, such as ascorbic acid and glutathione, were significantly higher in “Desi” than “Kabuli”. Superoxide dismutase and catalase activity did not differ significantly between the two types of chickpea, whereas on the 10th day, the activities of ascorbate peroxidase, dehydroascorbate reductase, and glutathione reductase were higher in “Desi”. These findings indicate that the greater stress tolerance in the “Desi” type may be ascribed to its superior ability to maintain better water status, which results in less oxidative damage. In addition, laboratory studies conducted by subjecting both types of chickpea to similar levels of polyethylene glycol-induced water stress and to 10 μ.mol/L abscisic acid indicated a greater capacity of the “Desi” type to deal with oxidative stress than the “Kabuli” type