Study on Relationship between Selected Independent Variables with Knowledge of the Mobile Agro-Advisory Services Using Farmers of Udupi District of Karnataka

The present study was conducted during 2016-17 in the Udupi district of Karnataka. Mobile phones play an important role in accessing the information about improved cultivation practices. In this study, we had analysed the relationship between independent variable and knowledge level of the farmers. We had selected total 13 independent variables for the study, three variables viz., education, achievement motivation and risk orientation showed positive and significant relationship at one per cent level of probability. Whereas, six variables viz., annual income, extension contact, scientific orientation,extension participation, mass media participation and innovativeness showed positive and significant relation at five per cent level of probability with knowledge level. The remaining four variables namely, age, family type, occupation and land holding and did not showed any significant relationship with knowledge leve

DNA Fingerprinting of Mycobacterium tuberculosis: Lessons Learned and Implications for the Future

DNA fingerprinting of Mycobacterium tuberculosis—a relatively new laboratory technique—offers promise as a powerful aid in the prevention and control of tuberculosis (TB). Established in 1996 by the Centers for Disease Control and Prevention (CDC), the National Tuberculosis Genotyping Surveillance Network was a 5-year prospective, population-based study of DNA fingerprinting conducted from 1996 to 2000. The data from this study suggest multiple molecular epidemiologic and program management uses for DNA fingerprinting in TB public health practice. From these data, we also gain a clearer understanding of the overall diversity of M. tuberculosis strains as well as the presence of endemic strains in the United States. We summarize the key findings and the impact that DNA fingerprinting may have on future approaches to TB control. Although challenges and limitations to the use of DNA fingerprinting exist, the widespread implementation of the technique into routine TB prevention and control practices appears scientifically justified

Evaluation of efficacy of submucosal tramadol after mandibular third molar surgery: a prospective pilot study

Background: Surgical extraction of mandibular third molar is one of the most commonly performed procedure in oral and maxillofacial surgery. Its removal causes swelling, trismus, and moderate to severe pain which can be treated with various NSAID’s drugs, which have numerous side effects and gastric disturbances. In order to bypass such disturbances, Tramadol may be considered as an alternative for such patients. The aim of the study was to evaluate analgesic efficacy of submucosal tramadol and its implication over swelling and mouth opening after mandibular third molar surgery.Methods: This is a prospective study where in after post-surgical extraction of mandibular third molar, efficacy of submucosal injection of tramadol is evaluated in terms of pain and its implication over swelling and mouth opening.Results: The present study suggested there was statistically significant VAS score for pain after submucosally injecting tramadol post-surgical extraction of mandibular third molar in the following visits- 4hourly, 8hourly and 24hourly. In respect to swelling, statistically significant values was noted during 24hr and 72 h our post extraction. Also in case of mouth opening, statistically significant values were found 24 hourly.Conclusions: The present pilot study concluded that submucosal tramadol post mandibular third molar extraction has been effective in reducing pain, limiting post-extraction swelling and less impacting mouth opening by inducing less complications thereby bypassing gastric disturbances

CLINICAL AND BIOCHEMICAL PROFILE OF STEROID-INDUCED DIABETES

ABSTRACTObjective: To study the clinical and biochemical profile of patients who develop steroid-induced diabetes (SID) and its predisposing factors.Methods: Non-diabetic patients aged ≥18 years started on steroids were considered eligible for the study. In every case after detailed examination,fasting plasma glucose (FPG), post-prandial plasma glucose (PPG), glycated hemoglobin, fasting insulin were measured prior to starting steroids andwas repeated in 1 week (day 3/4) after starting steroid according to standard guidelines. FPG and PPG were repeated periodically during follow-upof the patients. The utility of Indian diabetic risk score (IDRS) score in predicting the risk for SID was also assessed.stResult: Steroid-induced diabetes was found to be more in females than in males. IDRS is not useful in predicting the risk factors of SID. 97% of patientshad an elevation of post-prandial sugars with or without fasting hyperglycemia, but only 3% of patients had isolated elevation of fasting blood sugar.84% of patients developed SID during the 1 week of therapy. 33% of the cases SID persisted even after 1 month of stopping steroids and on a minimaldosage of steroids.stConclusion: Unlike type 2 diabetes, there were no significant risk factors such as age, family history of diabetes to develop SID and IDRS may not be asensitive tool for predicting risk factors of SID. Monitoring of post-prandial sugars as compared to fasting sugars is essential for the screening of SID.Cumulative dose of steroid may not be important to precipitate steroid diabetes.Keywords: Glucocorticoids, Diabetes, Post-prandial glucose, Indian Diabetic Risk Score

Sub-Riemannian Geometry and Time Optimal Control of Three Spin Systems: Quantum Gates and Coherence Transfer

Many coherence transfer experiments in Nuclear Magnetic Resonance Spectroscopy, involving network of coupled spins, use temporary spin-decoupling to produce desired effective Hamiltonians. In this paper, we show that significant time can be saved in producing an effective Hamiltonian, if spin-decoupling is avoided. We provide time optimal pulse sequences for producing an important class of effective Hamiltonians in three spin networks. These effective Hamiltonians are useful for coherence transfer experiments and implementation of quantum logic gates in NMR quantum computing. It is demonstrated that computing these time optimal pulse sequences can be reduced to geometric problems that involve computing sub-Riemannian geodesics on Homogeneous spaces

BRONCHOCONSTRICTION SECONDARY TO USE OF TOPICAL TIMOLOL IN A NON-ASTHMATIC PATIENT

Ophthalmic application of a non-selective beta blocker like timolol maleate is known to produce bronchoconstriction in asthmatic individuals or patients with obstructive lung diseases. Timolol-induced bronchoconstriction in a previously healthy young adult without any pulmonary disease is rare. We report a case of a young adult who developed bronchoconstriction following ocular instillation of timolol maleate ophthalmic solution when he was treated for open-angle glaucoma

A RARE CAUSE OF SEPTIC ARTHRITIS WITH PLEURAL EFFUSION: BURKHOLDERIA PSEUDOMALLEI

Melioidosis is a fatal disease, most prevalent in South-East Asia, Northern Australia, and the Indian subcontinent is caused by Gram-negative saprophyte Burkholderia pseudomallei. Septic arthritis due to melioidosis is very rare and should be a differential diagnosis in patient presenting with septic arthritis in endemic areas. It results in severe morbidity. Hence, we report a case of septic arthritis of left knee and hip in a young patient who later developed pleural effusion caused by B. pseudomallei.Keywords: Septic arthritis, Pleural effusion, Vietnamese bomb.Â

Evaluation of Onion Genotypes for Growth and Bulb Yield in Mid Hill of Nepal

Experiments were conducted at Horticulture Research Division (HRD), Khumaltar, Lalitpur; and Horticulture Research Station (HRS), Kimugaun, Dailekh in 2017/18 to evaluate the high yielding open pollinated genotypes of onion in mid hills of both locations.  Five onion genotypes namely AVON-1016, AVON-1027, AVON-1028, AVON-1052, AVON-1074 and AVON-1103 received from Asian Vegetable Research and Development Centre were evaluated with local check variety and recommended variety Red Creole in both locations in randomized complete block design with 4 replications. The main objective of the experiment is to findout the high yielding open pollinated onion genotypes for mid hill condition.The pooled analysis of data over locations showed significant differences on plant height, neck diameter, bulb diameter, weight of bulbs and adjusted bulb yield per hectare.   Introduced genotypes AVON 1027 (38.83 t/ha), AVON 1052 (31.97 t/ha) and AVON 1028 (31.48 t/ha) produced significantly higher yield than recommended and commercially cultivated check variety Red Creole (27.04 t/ha). Therefore the genotype AVON 1027 can be selected as the best genotype for growing in mid hills of Nepa

Hemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study

Objectives: We aimed to describe the variation of hemostasis proteins in children with bacterial infections due to different pathogens ( Neisseria meningitidis, Streptococcus pneumoniae, Staphylococcus aureus , and group A streptococcus [GAS]) and to study hemostasis proteins in relation to mortality. Design: Preplanned analysis in prospective cohort study. Setting: Hospitals in five European countries (Austria, The Netherlands, Spain, Switzerland, and the United Kingdom). Patients: Admitted children (2012-2016) with community-acquired infections due to meningococci ( n = 83), pneumococci ( n = 64), S. aureus (n = 50), and GAS ( n = 44) with available serum samples collected less than 48 hours after admission. Interventions: None. Measurements and main results: Fibronectin, plasminogen activator inhibitor type 1 (PAI-1), thrombomodulin, and a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13) were measured in serum in 2019-2020. Additionally, von Willebrand factor, protein C, protein S, and factor IX were measured in citrate plasma available from a subset of patients. Outcome measures included in-hospital mortality and disease severity (need for ventilation/inotropes, Pediatric Index of Mortality score).Of 241 children, 21 (8.7%) died and 177 (73.5%) were admitted to PICU. Mortality rate was similar for the pathogen groups. Levels of fibronectin and thrombomodulin differed for the different pathogens ( p < 0.05). Fibronectin levels were lower in GAS infections than in S. pneumoniae and S. aureus infections but did not differ from meningococcal infections. Thrombomodulin levels in meningococcal infections were higher than in S. aureus and pneumococcal infections. Overall, the area under the curve for mortality was 0.81 (95% CI, 0.70-0.92) for thrombomodulin and 0.78 (95% CI, 0.69-0.88) for ADAMTS-13. The association of each hemostasis protein did not vary across pathogens for any of the outcome measures. Conclusions: Hemostatic disturbances in childhood bacterial infections are not limited to meningococcal sepsis but occur with a comparable severity across nonmeningococcal infections. High thrombomodulin and high ADAMTS-13 had good discriminative ability for mortality. Our results emphasize the importance of hemostatic disturbances in meningococcal and nonmeningococcal pediatric bacterial infections