2 research outputs found
EmotIoT: an IoT system to improve users’ wellbeing
IoT provides applications and possibilities to improve people’s daily lives and business environments. However, most of these technologies have not been exploited in the field of emotions. With the amount of data that can be collected through IoT, emotions could be detected and anticipated. Since the study of related works indicates a lack of methodological approaches in designing IoT systems from the perspective of emotions and smart adaption rules, we introduce a methodology that can help design IoT systems quickly in this scenario, where the detection of users is valuable. In order to test the methodology presented, we apply the proposed stages to design an IoT smart recommender system named EmotIoT. The system allows anticipating and predicting future users’ emotions using parameters collected from IoT devices. It recommends new activities for the user in order to obtain a final state. Test results validate our recommender system as it has obtained more than 80% accuracy in predicting future user emotions
Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells.
Expanding the mass of pancreatic insulin-producing beta cells through re-activation of beta cell replication has been proposed as a therapy to prevent or delay the appearance of diabetes. Pancreatic beta cells exhibit an age-dependent decrease in their proliferative activity, partly related to changes in the systemic environment. Here we report the identification of CCN4/Wisp1 as a circulating factor more abundant in pre-weaning than in adult mice. We show that Wisp1 promotes endogenous and transplanted adult beta cell proliferation in vivo. We validate these findings using isolated mouse and human islets and find that the beta cell trophic effect of Wisp1 is dependent on Akt signaling. In summary, our study reveals the role of Wisp1 as an inducer of beta cell replication, supporting the idea that the use of young blood factors may be a useful strategy to expand adult beta cell mass