Preparation and characterization of quercetin-loaded lipid liquid crystalline systems

The aim of the present study was to investigate mixtures of soy phosphatidylcholine (SPC) and glycerol dioleate (GDO) as encapsulation matrices for antioxidant quercetin. The effects of quercetin loading into non-aqueous formulations, non-lamellar liquid crystalline phases and their colloidal dispersions were studied by using synchrotron small angle X-ray diffraction, dynamic light scattering, cryogenic electron microscopy and high performance liquid chromatography. Quercetin incorporation is discussed in the context of lipid aggregation behavior, self-assembled nanostructure and chemical stability. The obtained results show that SPC/GDO-based formulations can incorporate relatively high amounts of quercetin and serve as liquid crystalline delivery vehicles in the form of bulk phases or colloidal dispersions

Characterization and stability study of cranberry flavonoids in lipid liquid crystalline systems

The main objective of the present study was to investigate mixtures of soy phosphatidylcholine (SPC) and glycerol dioleate (GDO) as encapsulation matrices for cranberry flavonoids. The effects of flavonoids loading into non-aqueous formulations, non-lamellar liquid crystalline phases, and their colloidal dispersions were studied by using synchrotron small angle X-ray diffraction, dynamic light scattering. Flavonoids incorporation is discussed with respect to the lipid aggregation behavior, self-assembled nanostructure, and chemical stability by using antioxidant activity assay. The obtained results show that SPC/GDO-based formulations can incorporate relatively high amounts of flavonoids and serve as liquid crystalline delivery vehicles in the form of bulk phases or colloidal dispersions. Practical applications: Our results show that SPC/GDO-based formulations can incorporate relatively high amounts of cranberry flavonoids. The effect flavonoid extracts on the nanostructure of bulk SPC/GDO LC phases are lipid weight ratio-dependent. Flavonoids loaded into SPC/GDO-based formulations and LC phases retain their antioxidant properties. The self-assembled lipid liquid crystalline systems protect bioactive compounds from degradation. These facts are important for the community working in the field of self-assembly of lipid structures, food chemistry, and delivery vehicles of nutraceuticals

Relation between thickness, crystallitesize and magnetoresistance of nanostructuredLa1−xSrxMnyO3±δ films for magnetic field sensors

In the present study the advantageous pulsed-injection metal organic chemical vapour deposition (PI-MOCVD) technique was usedfor the growth of nanostructured La1−xSrxMnyO3±δ (LSMO) films on ceramic Al2O3 substrates. The compositional, structural andmagnetoresistive properties of the nanostructured manganite were changed by variation of the processing conditions: precursorsolution concentration, supply frequency and number of supply sources during the PI-MOCVD growth process. The results showedthat the thick (≈400 nm) nanostructured LSMO films, grown using an additional supply source of precursor solution in an exponen-tially decreasing manner, exhibit the highest magnetoresistance and the lowest magnetoresistance anisotropy. The possibility to usethese films for the development of magnetic field sensors operating at room temperature is discusse