Additional file 1 of Lymphocyte depletion and repopulation after chemotherapy for primary breast cancer

Table S1. Levels of peripheral blood lymphocytes of different subtypes do not differ in breast cancer patients pre-chemotherapy from control healthy women. Absolute numbers of the lymphocyte subgroups shown were determined by multi-parameter flow cytometry on peripheral blood samples taken from breast cancer patients before chemotherapy or from control health women. Data are shown as median absolute counts with interquartile ranges (brackets). (DOC 28 kb

Additional file 2 of Lymphocyte depletion and repopulation after chemotherapy for primary breast cancer

Figure S1. The proportion of CD4+ T cells defined as recent thymic emigrants is reduced after chemotherapy and shows no evidence of normalising. Recent thymic emigrant CD4+ T cells were quantified by multi-parameter flow cytometry and their numbers are presented as the proportion of the total CD4+ T cell pool. Data are shown for samples taken pre-chemotherapy (pre) and 3, 6, and 9 months (3m, 6m, 9m) after the end of chemotherapy. Boxes represent 50 % of the data, with medians (lines), interquartile ranges (whiskers) and individual outliers (circles). * p < 0.001. (TIF 192 kb