7 research outputs found
Decoupling social status and status certainty effects on health in macaques: a network approach.
BackgroundAlthough a wealth of literature points to the importance of social factors on health, a detailed understanding of the complex interplay between social and biological systems is lacking. Social status is one aspect of social life that is made up of multiple structural (humans: income, education; animals: mating system, dominance rank) and relational components (perceived social status, dominance interactions). In a nonhuman primate model we use novel network techniques to decouple two components of social status, dominance rank (a commonly used measure of social status in animal models) and dominance certainty (the relative certainty vs. ambiguity of an individual's status), allowing for a more complex examination of how social status impacts health.MethodsBehavioral observations were conducted on three outdoor captive groups of rhesus macaques (N = 252 subjects). Subjects' general physical health (diarrhea) was assessed twice weekly, and blood was drawn once to assess biomarkers of inflammation (interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and C-reactive protein (CRP)).ResultsDominance rank alone did not fully account for the complex way that social status exerted its effect on health. Instead, dominance certainty modified the impact of rank on biomarkers of inflammation. Specifically, high-ranked animals with more ambiguous status relationships had higher levels of inflammation than low-ranked animals, whereas little effect of rank was seen for animals with more certain status relationships. The impact of status on physical health was more straightforward: individuals with more ambiguous status relationships had more frequent diarrhea; there was marginal evidence that high-ranked animals had less frequent diarrhea.DiscussionSocial status has a complex and multi-faceted impact on individual health. Our work suggests an important role of uncertainty in one's social status in status-health research. This work also suggests that in order to fully explore the mechanisms for how social life influences health, more complex metrics of social systems and their dynamics are needed
Degree of similitude estimation for sub-scale flight testing
Sub-scaled Physical Models (SPM) are often employed in wind-tunnel tests or in free-flight tests (physical tests) to predict flight behavior of aircraft Full-scale Design (FD). However, a quality prediction of both the static and dynamic behavior is to date an open challenge. In this research, a methodology for designing SPMs is proposed for those cases where dynamic similarity between SPM and FD cannot be achieved and legacy information to compare subscale flight results to FD is unavailable. Instead of attempting to use just one SPM to achieve complete similarity with full scale design, this methodology enables the design and comparison of multiple SPMs to determine the Sub-scale Design (SD) best suited the estimation of specific aspect the FD flight behavior. To this purpose, a metric called Degree of Similitude (DoS) is defined, to quantify the similarity of FD and SPM based on the aerodynamic coefficients that are relevant for a given test. The DoS estimation first requires the evaluation of relevant aerodynamic coefficients, by means of Computational Fluid Dynamics (CFD). CFD analysis, requires complex geometry generation, adequate grid generation, expensive calculation and laborious post processing. To this purpose, a Knowledge Based Engineering (KBE) tool called Multi-model Generator (MMG) is developed, to automate all the labor intensive tasks in the evaluation of the DoS including the integration of CFD tool. Validation of results produced by MMG-VSAERO tool-chain is performed by means of a wind-tunnel test campaign using a 8.8% aerodynamically scaled SPM of the Cessna Citation II 550 (citation). The results of this test are compared with flight test data of full-scale aircraft (which is co-owned and operated by Delft University of Technology). Furthermore, this SPM was compared with three other Sub-scale Designs (SD) to estimate their DoS with the full-scale aircraft for two different eigenmodes, namely short period mode and phugoid mode. Of the four SDs compared, it was found that the geometrically scaled SD showed highest DoS for short period motion and one of the aerodynamically scaled SD had highest DoS for phugoid motion. From the cases studied, it can already be inferred that geometrically scaled SDs are not always preferred and in many cases, aerodynamically scaled SDs can be much more similar to FD. This case study proved the convenience of the proposed coefficient DoS which, in the next phase of the research, will be used as objective function to design optimum SPMs for a given test.Flight Performance and Propulsio
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Decoupling social status and status certainty effects on health in macaques: a network approach.
BackgroundAlthough a wealth of literature points to the importance of social factors on health, a detailed understanding of the complex interplay between social and biological systems is lacking. Social status is one aspect of social life that is made up of multiple structural (humans: income, education; animals: mating system, dominance rank) and relational components (perceived social status, dominance interactions). In a nonhuman primate model we use novel network techniques to decouple two components of social status, dominance rank (a commonly used measure of social status in animal models) and dominance certainty (the relative certainty vs. ambiguity of an individual's status), allowing for a more complex examination of how social status impacts health.MethodsBehavioral observations were conducted on three outdoor captive groups of rhesus macaques (N = 252 subjects). Subjects' general physical health (diarrhea) was assessed twice weekly, and blood was drawn once to assess biomarkers of inflammation (interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and C-reactive protein (CRP)).ResultsDominance rank alone did not fully account for the complex way that social status exerted its effect on health. Instead, dominance certainty modified the impact of rank on biomarkers of inflammation. Specifically, high-ranked animals with more ambiguous status relationships had higher levels of inflammation than low-ranked animals, whereas little effect of rank was seen for animals with more certain status relationships. The impact of status on physical health was more straightforward: individuals with more ambiguous status relationships had more frequent diarrhea; there was marginal evidence that high-ranked animals had less frequent diarrhea.DiscussionSocial status has a complex and multi-faceted impact on individual health. Our work suggests an important role of uncertainty in one's social status in status-health research. This work also suggests that in order to fully explore the mechanisms for how social life influences health, more complex metrics of social systems and their dynamics are needed
Parking infrastructure: energy, emissions, and automobile life-cycle environmental accounting
The US parking infrastructure is vast and little is known about its scale and environmental impacts. The few parking space inventories that exist are typically regionalized and no known environmental assessment has been performed to determine the energy and emissions from providing this infrastructure. A better understanding of the scale of US parking is necessary to properly value the total costs of automobile travel. Energy and emissions from constructing and maintaining the parking infrastructure should be considered when assessing the total human health and environmental impacts of vehicle travel. We develop five parking space inventory scenarios and from these estimate the range of infrastructure provided in the US to be between 105 million and 2 billion spaces. Using these estimates, a life-cycle environmental inventory is performed to capture the energy consumption and emissions of greenhouse gases, CO, SO2, NOX, VOC (volatile organic compounds), and PM10 (PM: particulate matter) from raw material extraction, transport, asphalt and concrete production, and placement (including direct, indirect, and supply chain processes) of space construction and maintenance. The environmental assessment is then evaluated within the life-cycle performance of sedans, SUVs (sports utility vehicles), and pickups. Depending on the scenario and vehicle type, the inclusion of parking within the overall life-cycle inventory increases energy consumption from 3.1 to 4.8 MJ by 0.1–0.3 MJ and greenhouse gas emissions from 230 to 380 g CO2e by 6–23 g CO2e per passenger kilometer traveled. Life-cycle automobile SO2 and PM10 emissions show some of the largest increases, by as much as 24% and 89% from the baseline inventory. The environmental consequences of providing the parking spaces are discussed as well as the uncertainty in allocating paved area between parking and roadways