Consort diagram.

<p>Consort diagram.</p

Protocol characteristics, overall observed, and estimated 2-year publication rates.

<p>Protocol characteristics, overall observed, and estimated 2-year publication rates.</p

Conditional probabilities of publication for trials not published by year 2.

<p>Conditional probabilities of publication for trials not published by year 2.</p

Response options in reporting reasons for non-publication of trials.

<p>Response options in reporting reasons for non-publication of trials.</p

Distribution of activation years.

<p>The year of activation at MSKCC is shown on the <i>x</i>-axis for the 809 protocols analyzed. Protocols for the year 2000 (N = 6 protocols) include 3 protocols activated in earlier years (1977, 1998, 1999). These protocols were collapsed into 2000 for clarity of the histogram.</p

Cumulative probability of publication.

<p>A) All protocols. Tick marks indicated censored (non-published) trials. B) Therapeutic (red) and non-therapeutic (green) protocols were plotted separately. Log-rank p = 0.025. C) Cumulative probability of publication based on type of sponsor. There was no significant differences between trials sponsored by industry (red line), National cooperative group trials (green), institutional sponsors (broken blue line), or by peer-reviewed grants (broken purple line). Log rank p = 0.673. D) Cumulative probability of publication based on phase of the trial. There was no significant differences between pilot trials (red), phase I (broken green line), phase II (broken blue line), phase III (broken purple line), and other trials (yellow) were plotted separately. Log rank p = .234.</p