131 research outputs found
Estimation of developed building land market value in the municipality of Slovenj Gradec
This thesis discusses the market value of developed building land in the Municipality of Slovenj Gradec. The discussed area is divided into two areas: areas and settlements with a predominantly residential land use and areas and settlements with a predominantly mixed residential and farmland land use. The average prices of the vacant building land for each area are presented and given are the way of calculating the public utilities fee in the Municipality of Slovenj Gradec as well as the comparison between the amount of the public utilities fee per unit between the two given areas. In the last part, the developed building land market value in the Municipality of Slovenj Gradec is evaluated. \ud
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Transforming Growth Factor-β1 Regulates the Expression of the High-Affinity Receptor for IgE on CD34+ Stem Cell-Derived CD1a+ Dendritic Cells In Vitro
It has been reported that monocytes, Langerhans cells (LC) and other dendritic cells (DC) express the high-affinity receptor for IgE (FcεRI) in patients with atopic diseases. These cells may be instrumental in the control of the immune response and the allergic inflammation. In this context, transforming growth factor beta 1 (TGF-β1) has been highlighted as a key cytokine involved in the mechanisms aimed to orchestrate tolerance and has been suggested as a candidate gene in atopic diseases. In this report, we investigate the putative role of TGF-β1 in the regulation of FcεRI on cord blood CD34+ stem cell-derived CD1a+ DC (CD34-derived CD1a+ DC). Kinetic experiments show that FcεRI spontaneously appears on the surface of CD1a+ DC, but decreases when exogenous TGF-β1 is added at high doses (10 ng per mL) or when endogenous TGF-β1 is neutralized in the culture conditions. In contrast, low-dose TGF-β1 (0.5 ng per mL) stabilizes surface FcεRI expression on DC. Increasing TGF-β1 concentrations leads to the generation of LC-like DC showing an augmentation in stimulatory capacity towards allogeneic T cells. In view of these data, a picture emerges that FcεRI+ on DC is finely modified by the TGF-β1 concentration in the microenvironment and could be of primary relevance in the context of atopic diseases
Recurrent eczema herpeticum – a retrospective European multicenter study evaluating the clinical characteristics of eczema herpeticum cases in atopic dermatitis patients
Background
Eczema herpeticum (EH ) is a disseminated viral infection of eczematous skin disease with the herpes simplex virus. Knowledge on clinical characteristics, risk factors and recurrent disease is limited. Our aim was to better define clinical characteristics and risk factors for EH and especially for recurrent EH .
Methods
A retrospective analysis of EH cases assessed the history, clinical signs, prior treatment and laboratory results using a predefined questionnaire.
Results
A total of 224 EH cases from eight European centres were included. Extrinsic AD was identified as risk factor for EH , and only one patient suffered from intrinsic AD . Early onset of AD was identified as risk factor for recurrent EH . Pretreatment with topical steroids, systemic steroids, topical calcineurin inhibitors or plain emollients reflected standard therapy. Many patients showed AD lesions without EH , but skin without AD lesions was never affected by herpetic lesions.
Conclusion
Patients with clinically active, extrinsic AD are at risk of EH . Recurrent EH is associated with confounders of severe atopic distortion and requires active AD lesions for clinical manifestation. Recurrent eczema herpeticum mainly affects patients with early onset of AD
Klinična pot dela genomskega svetovalca v procesu obravnave pacienta v Ambulanti za onkološko genetsko svetovanje in testiranje Oddelka za onkološko klinično genetiko
ALLELOPATHIC EFFECT OF TWO WEED SPECIES, ABUTILON THEOPHRASTI MED. AND DATURA STRAMONIUM L. ON GERMINATION AND EARLY GROWTH OF CORN
U cilju smanjenja primjene kemijskih sredstava za zaštitu bilja novija istraživanja znanstvenika, sve više su usmjerena na različite alternativne „nekemijske“ mjere borbe protiv štetočinja. Od njih se traži da budu približno učinkovite kao kemijske mjere, a da manje štete okolišu. Alelokemijske sposobnosti biljaka uočene su već u 3. st. prije Krista ali su se tek u 20. st. počele intenzivno proučavati. Cilj ovog rada bio je proučiti alelokemijske sposobnosti dviju korovnih pridošlica u Republiku Hrvatsku, mračnjaka - Abutilon theophrasti Med. (ABUTH) i kužnjaka - Datura stramonium L. (DATST). U tu svrhu postavljena su dva pokusa kojima se ispitivao alelopatski utjecaj biljne mase ekstrakta nadzemnog i podzemnog dijela mračnjaka kao i vodenog ekstrakta nadzemnih dijelova kužnjaka na početni rast i razvoj kukuruza (Zea mays L.). Ocjena alelopatskog utjecaja utvrđena je mjerenjem ukupnog postotka klijavosti, duljine korijenka i klice kukuruza. Istraživanjima je dokazan izrazit inhibirajući učinak korovne vrste Abutilon theophrasti Med. na duljinu korijenka, klice kao i na ukupnu klijavost zrna kukuruza. Korovna vrsta Datura stramonium L. imala je suprotan, odnosno stimulirajući učinak na duljinu korijenka kukuruza. Primjenom ekstrakta iz nadzemnih dijelova obje istraživane korovne vrste smanjena je ukupna klijavost zrna kukuruza mjerena tri, šest i 10 dana nakon tretiranja. Provedenim pokusima dokazane su, inhibirajuće i stimulirajuće alelopatske interakcije između dviju istraživanih korovnih vrsta i kukuruza.In view of minimising the use of pesticides in agriculture, scientific researchers all over the world are oriented to ther “alternative”, “non-chemical” weed control measures which are required to be efficient as chemicals but should be beneficial to the environment. Although allelopathy interactions between plants were observed in the 3rd century BC, allelopathy and allelochemicals started to play an important role in agriculture in the 20th. The aim of this paper was to investigate the allelopathic effect of two important non-native weed species in Croatia, Abutilon theophrasti Med. (ABUTH) and Datura stramonium L. (DATST). Both of the weeds are very competitive in corn crops and cause great losses in corn yields. Laboratory experiments were conducted in 2004. and 2005. In the first experiment allelopathic effect of aqueous extract of fresh shoot and leaves, and separately aqueous extract of roots of Abutilon theophrast Med. on germination and early growth of corn (Zea mays L.) were examined. In the second experiment allelopathic effect of above part of plant of both weeds were examined only. Aqueous extracts of Abutilon theophrasti Med. inhibited strong germination, radicle and coleoptile length of corn. On the other side promoting effect on radicle length was noticed by aqueous extract of Datura stramonium L. Germination of corn, measured 3, 6 and 10 days after treatments, was inhibited by aqueous extracts of above ground part of plants of both weed species
ALLELOPATHIC EFFECT OF TWO WEED SPECIES, ABUTILON THEOPHRASTI MED. AND DATURA STRAMONIUM L. ON GERMINATION AND EARLY GROWTH OF CORN
U cilju smanjenja primjene kemijskih sredstava za zaštitu bilja novija istraživanja znanstvenika, sve više su usmjerena na različite alternativne „nekemijske“ mjere borbe protiv štetočinja. Od njih se traži da budu približno učinkovite kao kemijske mjere, a da manje štete okolišu. Alelokemijske sposobnosti biljaka uočene su već u 3. st. prije Krista ali su se tek u 20. st. počele intenzivno proučavati. Cilj ovog rada bio je proučiti alelokemijske sposobnosti dviju korovnih pridošlica u Republiku Hrvatsku, mračnjaka - Abutilon theophrasti Med. (ABUTH) i kužnjaka - Datura stramonium L. (DATST). U tu svrhu postavljena su dva pokusa kojima se ispitivao alelopatski utjecaj biljne mase ekstrakta nadzemnog i podzemnog dijela mračnjaka kao i vodenog ekstrakta nadzemnih dijelova kužnjaka na početni rast i razvoj kukuruza (Zea mays L.). Ocjena alelopatskog utjecaja utvrđena je mjerenjem ukupnog postotka klijavosti, duljine korijenka i klice kukuruza. Istraživanjima je dokazan izrazit inhibirajući učinak korovne vrste Abutilon theophrasti Med. na duljinu korijenka, klice kao i na ukupnu klijavost zrna kukuruza. Korovna vrsta Datura stramonium L. imala je suprotan, odnosno stimulirajući učinak na duljinu korijenka kukuruza. Primjenom ekstrakta iz nadzemnih dijelova obje istraživane korovne vrste smanjena je ukupna klijavost zrna kukuruza mjerena tri, šest i 10 dana nakon tretiranja. Provedenim pokusima dokazane su, inhibirajuće i stimulirajuće alelopatske interakcije između dviju istraživanih korovnih vrsta i kukuruza.In view of minimising the use of pesticides in agriculture, scientific researchers all over the world are oriented to ther “alternative”, “non-chemical” weed control measures which are required to be efficient as chemicals but should be beneficial to the environment. Although allelopathy interactions between plants were observed in the 3rd century BC, allelopathy and allelochemicals started to play an important role in agriculture in the 20th. The aim of this paper was to investigate the allelopathic effect of two important non-native weed species in Croatia, Abutilon theophrasti Med. (ABUTH) and Datura stramonium L. (DATST). Both of the weeds are very competitive in corn crops and cause great losses in corn yields. Laboratory experiments were conducted in 2004. and 2005. In the first experiment allelopathic effect of aqueous extract of fresh shoot and leaves, and separately aqueous extract of roots of Abutilon theophrast Med. on germination and early growth of corn (Zea mays L.) were examined. In the second experiment allelopathic effect of above part of plant of both weeds were examined only. Aqueous extracts of Abutilon theophrasti Med. inhibited strong germination, radicle and coleoptile length of corn. On the other side promoting effect on radicle length was noticed by aqueous extract of Datura stramonium L. Germination of corn, measured 3, 6 and 10 days after treatments, was inhibited by aqueous extracts of above ground part of plants of both weed species
Uzroci, posljedice i prevencija prekomjerna pjenjenja piva
Prekomjerno pjenjenje piva (engl. beer gushing) definira se kao naglo i nekontrolirano pjenjenje piva odmah po otvaranju ambalaže, bez prethodnog izlaganja ambalaže trešnji ili visokoj temperaturi. Ta je pojava uzrok velikim gubitcima u sladarama i pivovarama širom svijeta te se smatra iznimno nepoželjnom. Razlikujemo primarno i sekundarno prekomjerno pjenjenje piva. Fungalne kontaminacije ječma, posebno kontaminacija plijesnima roda Fusarium, izravno se povezuju s pojavom primarnog prekomjernog pjenjenja piva. Ove plijesni sintetiziraju male proteine nazvane hidrofobini, koji se navode kao glavni uzročnici prekomjernog pjenjenja piva. Uzročnici sekundarnog prekomjernog pjenjenja piva su brojniji i uključuju različite kemikalije i postupke koji se upotrebljavaju tijekom proizvodnje piva. Sekundarno pjenjenje piva uglavnom se može izbjeći primjenom dobre proizvođačke prakse, dok je problem učinkovitog suzbijanja primarnog prekomjernog pjenjenja piva još uvijek predmet brojnih istraživanja
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