Detailed characterization of a laboratory magnetized supercritical collisionless shock and of the associated proton energization

Collisionless shocks are ubiquitous in the Universe and are held responsible for the production of nonthermal particles and high-energy radiation. In the absence of particle collisions in the system, theory shows that the interaction of an expanding plasma with a pre-existing electromagnetic structure (as in our case) is able to induce energy dissipation and allow shock formation. Shock formation can alternatively take place when two plasmas interact, through microscopic instabilities inducing electromagnetic fields that are able in turn to mediate energy dissipation and shock formation. Using our platform in which we couple a rapidly expanding plasma induced by high-power lasers (JLF/Titan at LLNL and LULI2000) with high-strength magnetic fields, we have investigated the generation of a magnetized collisionless shock and the associated particle energization. We have characterized the shock as being collisionless and supercritical. We report here on measurements of the plasma density and temperature, the electromagnetic field structures, and the particle energization in the experiments, under various conditions of ambient plasma and magnetic field. We have also modeled the formation of the shocks using macroscopic hydrodynamic simulations and the associated particle acceleration using kinetic particle-in-cell simulations. As a companion paper to Yao et al. [Nat. Phys. 17, 1177-1182 (2021)], here we show additional results of the experiments and simulations, providing more information to allow their reproduction and to demonstrate the robustness of our interpretation of the proton energization mechanism as being shock surfing acceleration

Laboratory evidence for proton energization by collisionless shock surfing

Charged particles can be accelerated to high energies by collisionless shock waves in astrophysical environments, such as supernova remnants. By interacting with the magnetized ambient medium, these shocks can transfer energy to particles. Despite increasing efforts in the characterization of these shocks from satellite measurements at Earth’s bow shock as well as powerful numerical simulations, the underlying acceleration mechanism or a combination thereof is still widely debated. Here we show that astrophysically relevant super-critical quasi-perpendicular magnetized collisionless shocks can be produced and characterized in the laboratory. We observe the characteristics of super-criticality in the shock profile as well as the energization of protons picked up from the ambient gas to hundreds of kiloelectronvolts. Kinetic simulations modelling the laboratory experiment identified shock surfing as the proton acceleration mechanism. Our observations not only provide direct evidence of early-stage ion energization by collisionless shocks but also highlight the role played by this particular mechanism in energizing ambient ions to feed further stages of acceleration. Furthermore, our results open the door to future laboratory experiments investigating the possible transition to other mechanisms, when increasing the magnetic field strength, or the effect that induced shock front ripples could have on acceleration processes

On the possibility of laser-plasma-induced depopulation of the isomer in ⁹³Mo at ELI-NP

High-power PW laser systems (HPLS) provide intense beams of accelerated reaction-driving protons simultaneously with spatially localized keV-plasmas. We herein depict our groundwork and strategy to use these unique features of the HPLS at the Extreme Light Infrastructure (ELI-NP) by exposing the long-lived nuclear isomer 93mMo at 2.425 MeV (t1/2 = 6.85 h) to plasma facilitating the local petawatt beamlines. An intermediate short-lived (t1/2 = 3.52 ns) state situated only 4.85 keV above 93mMo constitutes a gateway to allow for its prompt release. The controllable release of the nuclear isomer energy will henceforth enable harvesting energy densities in the nuclear regime of GJkg-1 (‘Nuclear Battery’). The campaign was inspired by the observation of the triggered release of via the intermediate state by Chiara et al. [1] published in Nature. They assigned the hitherto elusive Nuclear Excitation by Electron Capture (NEEC) as the driving process and claimed a very high probability of PexpNEEC= 0.010(3). However, these claims are challenged by experimentalists [2, 3] and theory [4]. We herein outline our strategy following bespoke theoretical guidance in the quest to unambiguously and independently demonstrate the onset of NEEC in 93mMo. With the yield estimations derived for our forthcoming HPLS experiment at ELI-NP, we draw optimism to resolve the current conundrum between the conflicting experimental observations and theoretical interpretations as discussed in world-leading journals and to pave the way for the future utilization of isomer depopulation in applied physics

Species distribution and susceptibility profile to fluconazole, voriconazole and MXP-4509 of 551 clinical yeast isolates from a Romanian multi-centre study

This is the first multi-centre study regarding yeast infections in Romania. The aim was to determine the aetiological spectrum and susceptibility pattern to fluconazole, voriconazole and the novel compound MXP-4509. The 551 isolates were identified using routine laboratory methods, matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) and DNA sequence analysis. Susceptibility testing was performed using the European Committee for Antimicrobial Susceptibility Testing (EUCAST) method and breakpoints. The yeasts originated from superficial infections (SUP, 51.5 %), bloodstream infections (BSI, 31.6 %) and deep-seated infections (DEEP, 16.9 %), from patients of all ages. Nine genera and 30 species were identified. The 20 Candida species accounted for 94.6 % of all isolates. C. albicans was the overall leading pathogen (50.5 %). Lodderomyces elongisporus is reported for the first time as a fungaemia cause in Europe. C. glabrata and Saccharomyces cerevisiae, as well as the non-Candida spp. and non-albicans Candida spp. groups, showed decreased fluconazole susceptibility (<75 %). The overall fluconazole resistance was 10.2 %. C. krusei accounted for 27 of the 56 fluconazole-resistant isolates. The overall voriconazole resistance was 2.5 % and was due mainly to C. glabrata and C. tropicalis isolates. Fluconazole resistance rates for the three categories of infection were similar to the overall value; voriconazole resistance rates differed: 4 % for BSI, 3.2 % for DEEP and 1.4 % for SUP. The antifungal activity of MXP-4509 was superior to voriconazole against C. glabrata and many fluconazole-resistant isolates. There was a large percentage of non-albicans Candida isolates. A large part of the high fluconazole resistance was not acquired but intrinsic, resulting from the high percentage of C. krusei

Detailed characterization of laboratory magnetized super-critical collisionless shock and of the associated proton energization

International audienceCollisionless shocks are ubiquitous in the Universe and are held responsible for the production of non-thermal particles and high-energy radiation.In the absence of particle collisions in the system, theoretical works show that the interaction of an expanding plasma with a pre-existing electromagnetic structure (as in our case) is able to induce energy dissipation and allow for shock formation. Shock formation can alternatively take place when two plasmas interact, throughmicroscopic instabilities inducing electromagnetic fields which are able in turn to mediate energy dissipation and shock formation. Using our platform where we couple a fast expanding plasma induced by high-power lasers (JLF/Titan at LLNL and LULI2000) with high-strength magnetic fields, we have investigated the generation of magnetized collisionless shock and the associated particle energization. We have characterized the shock to be collisionless and super-critical.We report here on measurements of the plasma density, temperature, the electromagnetic field structures, and particle energization in the experiments, under various conditions of ambient plasma and B-field. We have also modelled the formation of the shocks using macroscopic hydrodynamic simulations and the associated particle acceleration using kinetic particle-in-cell simulations. As a companion paper of \citet{yao2020laboratory}, here we show additional results of the experiments and simulations, providing more information to reproduce them and demonstrating the robustness of our interpreted proton energization mechanism to be shock surfing acceleration