THE EFFECT OF MATERNAL ANEMIA ON THE ANTHROPOMETRIC MEASUREMENTS IN FULLTERM NEONATES

 Objective: The current study was performed to understand the effect of maternal anemia and its severity on anthropometric measurement of full-term neonates.Methods: In this study, 254 pregnant women were involved in this study. The women with anemia were classified depending on the hemoglobin concentration into three groups of mild (10.9–9.0 g/dl), moderate (8.9–7.0 g/dl), and severe anemia (˂7.0 g/dl). The anthropometric measurements of the newborns were measured including birth weight, length, and head and chest circumference. Mothers with chronic diseases, preterm neonates, postdate neonates, neonates with congenital anomalies, or critical illnesses had been excluded from the study.Results: A total of 147 (58%) mothers had normal hemoglobin levels, and 107 (42%) mothers were anemic. The newborns were 123 males and 131 females. From the anemic mothers, 59 (55%) neonates had low weight, and 48 (45%) neonates had normal weight. In mothers with mild anemia (n=83), 40 (48%) neonates had low weight. In mothers with moderate anemia (n=21), 16 (76%) neonates had low weight. In mothers with severe anemia (n=3), all of their neonates had low weight. The current study revealed a statistically significant difference (p=0.002) in the anthropometric measurement of the full-term neonates between anemic and non-anemic mothers. There was also a statistically significant difference (p=0.001) in the anthropometric measurement of the full-termed neonates between severely and mildly anemic mothers.Conclusion: The current study shows that maternal anemia affects the anthropometric measurements of newly delivered full-term neonates. Neonates born to anemic mothers had low birth weight and shorter length than those in neonates who were born to non-anemic mothers

Rhythm As Creative System In Houses Architecture Comparative Application Study Between Heritage And Contemporary Houses

Rhythm is considered one of the creative concepts in the recent architectural thought; it has emerged clearly as a mean of creating the highest levels of creativity in architecture, especially in contemporary architectural movements. The importance of rhythm has  emerged, especially, when the architecture , its beginnings concentrated on the principle of the links with poetic structures. Many architectural studies deal with concept of rhythm in architecture with different ways various according to the trend of each study, this show the importance of studying the concept of rhythm in the architectural field in general. This study try to focus on the utilization of rhythm as creative system in architecture of heritage and contemporary house because its important in the generation of new architectural models. The paper discusses the importance of this concept and its utilization in the designs, in order to explore the particular problem which has been represented as (The absence of a specific imagination of methods and strategies for achieving rhythm).Thus the objectives of the paper has been formed by building theoretical framework consisting of five main items of detailed theoretical field which specifies rhythm as a concept ,firstly, then the application of the important heritage and contemporary houses in Mosul Architecture as a model, concluding utilization of rhythm as creative system in Heritage and Contemporary Houses in Mosul Architecture, finally, after discussing the results to submit the conclusions in the end. The conclusion is That suitable rhythm creativity in Mosul architecture is by unit and immerge the Mosul cultural elements as new tool in steps of design process of Heritage and Contemporary Houses in Mosul

The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG

The ERG (ETS-related gene) transcription factor is linked to various types of cancer, including leukemia. However, the specific ERG domains and co-factors contributing to leukemogenesis are poorly understood. Drug targeting a transcription factor such as ERG is challenging. Our study reveals the critical role of a conserved amino acid, proline, at position 199, located at the 3' end of the PNT (pointed) domain, in ERG's ability to induce leukemia. P199 is necessary for ERG to promote self-renewal, prevent myeloid differentiation in hematopoietic progenitor cells, and initiate leukemia in mouse models. Here we show that P199 facilitates ERG's interaction with the NCoR-HDAC3 co-repressor complex. Inhibiting HDAC3 reduces the growth of ERG-dependent leukemic and prostate cancer cells, indicating that the interaction between ERG and the NCoR-HDAC3 co-repressor complex is crucial for its oncogenic activity. Thus, targeting this interaction may offer a potential therapeutic intervention

Dielectric properties of Li doped Ni-Zn ferrite

Lithium doped Nickel-Zinc ferrite material with chemical formula Ni0.9−2x Zn0.1LixFe2+xO4, where x is the ratio of lithium ions Li+ (x = 0, 0.01, 0.02, 0.03 and 0.04) prepared by using sol-gel auto combustion technique. X-ray diffraction results showed that the material have pure cubic spinal structure with space group Fd-3m. The experimental values of the lattice constant (aexp) were decreased from 8.39 to 8.35 nm with doped Li ions. It was found that the decreasing of the crystallite size with addition of lithium ions concentration. The radius of tetrahedral (rtet) and octahedral (roct) site were computed from cation distribution. SEM images have been taken to show the morphology of compound. The dielectric parameters [dissipation factor (Df), the dielectric constant (Ԑ') and a.c. conductivity (ζac)] of spinal ferrite nano-powder have been measured. The dielectric parameters as a function of concentration have been studied for ferrite synthesis. The saturation of magnetization (Ms), remiensis (Mr) and coersivity (Hc) were found from hysteresis loop. The Ms and Hc varied from 36.47 to 66.15 emu/gm and 103 to 133 Oe for ferrite synthesis, respectively

Optimization of vitexin and isovitexin compounds extracted from dried Mas Cotek leaves using one-factor-at-a-time (OFAT) approach in aqueous extraction

Mas Cotek or Ficus deltoidea is regarded as one of the most precious herbal plants in Malaysia due to its content of beneficial active compounds and appreciation as a traditional remedy. This research investigated performance of aqueous or water extraction of dried Mas Cotek leaves for vitexin and isovitexin compounds using three regiments of temperatures (50, 70 and 100°C) in sample-to-water ratios of 1:10, 1:20 and 1:30g/mL during 8 hours of extraction. The optimum yield recorded for vitexin compound was 0.463 ± 0.045 (%w/w) from; 1:30 g/mL sampleto-water ratio, 50°C temperature at 4th hour of extraction. While for isovitexin compound, the optimum value recorded was 0.136 ± 0.015 (%w/w) from; 1:20 (g/mL) sample-to-water ratio, 50°C temperature at 5th hour of extraction. The morphological characterization of the extracted dried leaves particles performed using FE-SEM showed an intact and less damaged surface of extracted sample after 8 hours of extraction. The experimental values under best conditions were consistent with the predicted values, which suggested that aqueous extraction of Mas Cotek leaves is a good platform to serve as baseline study for more advanced extraction techniques

Availability of rehabilitation services for communication disorders in Sri Lanka: a cross-sectional survey

Objectives To describe the rehabilitation services available for communication disorders in Sri Lanka and to estimate the adequacy of the services in provinces and districts of the country.Setting The study considered government and private institutions, which provide rehabilitation services for communication disorders in Sri Lanka.Participants Institutions providing services of speech–language pathologists, audiologists and audiology technicians in Sri Lanka.Primary and secondary outcome measures We investigated the number of government hospitals and private institutions, which provide speech–language pathology and audiology services in Sri Lanka as the primary outcome measure. A number of speech–language pathologists, audiologists and audiology technicians working in the institutions were obtained from records and institution-based inquiries to identify the adequacy of the services in the country as the secondary outcome measure.Results Of the 647 government hospitals that provide free healthcare services in the country, 45 and 33 hospitals had speech and language therapy and audiology units, respectively. Government hospitals do not have audiologists but only have audiology technicians. The number of speech and language therapists and audiology technicians in the government sector per 100 000 population in the country was 0.44 and 0.18, respectively. There were wide variations in specialist to population ratio between districts. 77 private centres provide speech therapy services in 15 out of the 25 districts; 36 private centres provide audiological evaluations in 9 districts.Conclusions The number of specialist speech and language therapists and audiologists is not sufficient to provide adequate rehabilitation services for communications disorder for the Sri Lankan population. Not recruiting audiologists to the government sector affects the management of hearing impairment in the affected

The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG

Abstract The ERG (ETS-related gene) transcription factor is linked to various types of cancer, including leukemia. However, the specific ERG domains and co-factors contributing to leukemogenesis are poorly understood. Drug targeting a transcription factor such as ERG is challenging. Our study reveals the critical role of a conserved amino acid, proline, at position 199, located at the 3’ end of the PNT (pointed) domain, in ERG’s ability to induce leukemia. P199 is necessary for ERG to promote self-renewal, prevent myeloid differentiation in hematopoietic progenitor cells, and initiate leukemia in mouse models. Here we show that P199 facilitates ERG’s interaction with the NCoR-HDAC3 co-repressor complex. Inhibiting HDAC3 reduces the growth of ERG-dependent leukemic and prostate cancer cells, indicating that the interaction between ERG and the NCoR-HDAC3 co-repressor complex is crucial for its oncogenic activity. Thus, targeting this interaction may offer a potential therapeutic intervention