426 research outputs found
Pierre Robin syndrome: a case report
Pierre Robin syndrome is characterized by micrognathia, glossoptosis and palatal malformation. We report a case of a 6 day neonate who presented with complaints of feeding and respiratory difficulty and was later diagnosed as case of Pierre Robin syndrome
Document clustering for knowledge synthesis and project portfolio funding decision in R&D organizations
The paper discusses a method of using document clustering for information/knowledge synthesis and decision facilitation in R&D organisations. The emerging methodologies of machine learning, artificial intelligence and data science in conjunction with fuzzy mathematics can be optimally exploited to catalyse development of information bank for research organisations. This knowledge ecosystem can be utilized by the proposed mechanism to accelerate and reinforce interdisciplinary research for R&D organisations and empower them to make efficacious information-driven decisions related to project portfolio selection and proposal funding
Deep Reinforcement Learning with Importance Weighted A3C for QoE enhancement in Video Delivery Services
Adaptive bitrate (ABR) algorithms are used to adapt the video bitrate based
on the network conditions to improve the overall video quality of experience
(QoE). Recently, reinforcement learning (RL) and asynchronous advantage
actor-critic (A3C) methods have been used to generate adaptive bit rate
algorithms and they have been shown to improve the overall QoE as compared to
fixed rule ABR algorithms. However, a common issue in the A3C methods is the
lag between behaviour policy and target policy. As a result, the behaviour and
the target policies are no longer synchronized which results in suboptimal
updates. In this work, we present ALISA: An Actor-Learner Architecture with
Importance Sampling for efficient learning in ABR algorithms. ALISA
incorporates importance sampling weights to give more weightage to relevant
experience to address the lag issues with the existing A3C methods. We present
the design and implementation of ALISA, and compare its performance to
state-of-the-art video rate adaptation algorithms including vanilla A3C
implemented in the Pensieve framework and other fixed-rule schedulers like BB,
BOLA, and RB. Our results show that ALISA improves average QoE by up to 25%-48%
higher average QoE than Pensieve, and even more when compared to fixed-rule
schedulers.Comment: Number of pages: 10, Number of figures: 9, Conference name: 24th IEEE
International Symposium on a World of Wireless, Mobile and Multimedia
Networks (WoWMoM
Klippel-Feil syndrome: a case report
Klippel-Feil Syndrome (KFS) is defined as congenital fusion of two or more cervical vertebrae. The most common signs are short neck, low hairline at the back of head and restricted mobility of neck. We report a case of a neonate who presented with complaint of respiratory difficulty and later diagnosed as case of Klippel-Feil syndrome
Formulation, Development and Evaluation of Montelukast Sodium Chewable Tablets.
The oral route of drug administration is the most important method of administering drug for systemic effects. Except in certain case the parental route is not routinely used for self administration, e.g. insulin. The topical route of administration has only recently been employed to deliver drugs to the body for systemic effect. The parental route of administration is important in treating medical emergencies in which the subject is comatose or cannot swallow. Nevertheless it is probable that at least 90% of all drugs used to provide systemic effect are administered by oral route. When a new drug is discovered one of the first question a pharmaceutical company asks is whether or not the drug can be effectively administered for its intended effect by oral route. Drugs that are administered orally, solid oral dosage forms represent the preferred class of product. Tablet and capsules represent unit dosage forms in which usual dose of drug has been accurately placed. It can be concluded that chewable tablets of Montelukast sodium can be prepared by wet granulation method using croscarmellose sodium as superdisintegrant. Chewable tablets of Montelukast sodium with 3% of croscarmellose sodium gave better drug release of 98% with minimum disintegration time with pleasant taste .This will improve patient compliance and increase in bioavailability
Development of gum acacia-alginate microspheres of metformin hydrochloride: In vitro characterization
The metabolic disorder type 2 diabetes mellitus continuously increasing in the world. This disorder affecting all age groups. Thus, this disorder is now creating burden on healthcare sector, especially in case of underdeveloped countries. Nowadays many conventional drug delivery systems are available for management of diabetes mellitus. The gums and mucilages are polysaccharide obtained from various plant. Thus, present study is started with aim to formulate gum acacia based microspheres for gastroretentive delivery of metformin hydrochloride. The drug loaded microspheres were formulated using ionic gelation method and evaluated for physicochemical properties, mucoadhesive potential, swelling index and in vitro drug release study. The microspheres showed acceptable physicochemical properties, good swelling ability, mucoadhesive potential and sustained drug release. Thus, gum acacia could be promising alternative for fabrication of gastroretentive drug delivery system. 
Neurological manifestations in speech after snake bite: a rare case
The patient was admitted after reporting a snake bite from which he later developed neurological signs and symptoms among which a flaccid dysarthria. The patient underwent speech therapy and showed significant improvement over a short period of time. The favorable outcome of the present study highlights the role of speech therapy in such a case, where it often remains un-emphasized
Complementary Organizational Mechanisms: A Case Study on Information Technology Business Value
The complex relationships between organizational practices have been the focus of information technology business value (ITBV) research in recent years. There appears to be a discernible trend toward a more nuanced view in which the effects of information technology (IT), various organizational practices and their relationships are systematically investigated. There is also emerging evidence of recent focus in organizational factors and an increasing shift towards “complementarities” in which organizational performance is linked to combining organizational practices in synergistic ways. The objective of this paper is to investigate important issues in ITBV research by examining complementarities of various resources within an organization. The goal of this paper is to establish a framework for analyzing different configurations of complementarities. The Configuration and Interestingness framework (CIF) proposed in this paper provides evidence on how important the understanding of those complex relationship structures amongst organizational practices is to maximizing business value. This framework serves as a preliminary attempt to reveal different possible classes of complementarities structures
Causality between Electricity Consumption & Economic growth : Empirical Evidence from India
In this study ,an attempt has been made to investigate causality between electricity consumption and economic growth in India by adopting Granger Engel causality model for 1960-2006 period .Test results shows that electricity consumption has positive effect on economic growth. The paper support for the reforms in power sector and indicates that electricity act as a catalyst in realizing various social and economic goals
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