43 research outputs found
<Abstract of published report>Effect of Suplatast Tosilate (IPD-1151T) on Types I-IV Allergic Reactions.
Get PDF<Abstract of published report>The Effects of Mesoporphyrin on Experimental Arthritis in Mice.
Get PDF<Review>MET-88 : Sarcoplastic Reticulum Ca^<2+>-Uptake Stiumlator for Treating Chronic Heart Failure
Get PDFMET-88,an inhibitor of γ-butyrobetaine hydroxylase, can be characterized as a unique cardioprotective agent for the treatment of congestive heart failure (CHF) with an ability to regulate the activity of SR Ca^-ATPase. MET-88 protected the hypoxic and ischemic myocardium due to the modulation of myocardial metabolism and improved cardiac remodeling and hypertrophy as effectively as captopril. MET-88 also increased the failed Ca^-ATPase activity in the Sarcoplastic reticulum (SR), which increase might have resulted from ATP synthesis through glycolysis. These effects of MET-88 may be expected to improve mortality, prognosis, and exercise intolerance in CHF patients. In summary, MET-88 may be a useful drug for the treatment of CHF
<Abstract of published report>Suppression of IgE Production by IPD-1151T (Suplatast Tosilate), a New Dimethylsulfonium Agent : (2) Regulation of Human IgE Response.
Get PDF<Abstract of published report>Suppression of IgE Production by IPD-1151T (Suplatast Tosilate), a New Dimethylsulfonium Agent : (1) Regulation of Murine IgE Response.
Get PDF<Abstract of annual report>Pharmacological study of Phospholipase A_2-induced histamine release from rat peritoneal mast cells.
Get PDF<Abstract of annual report>Effect of OKY-046,a New Thromboxane A_2 Synthetase Inhibitor, on Experimental Asthma in Guinea Pigs.
Get PDF<Abstract of Published Report>The Expression of Murine Cutaneous Late Phase Reaction Requires Both IgE Antibodies and CD4 T Cells.
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