34 research outputs found
Coexisting intracranial tumors with pituitary adenomas: Genetic association or coincidence?
The co-occurrence of two or more brain tumors with different
histological features is rare. The authors report three rare cases of
intracranial tumors associated with pituitary adenomas. Two of the
pituitary tumors were functioning adenomas: a prolactinoma and a
thyrotropin secreting adenoma. Two of the associated intracranial
neoplasms were gliomas and one was a meningioma. Radiological and
clinical examination for syndromal association was negative in all
cases. We briefly discuss the presentation and treatment options of
these cases and review the 19 previous publications in the literature
of pituitary tumors occurring in association with other neoplasms and
explore the possible links underlying these co-occurring neoplasms. Our
three cases represent 0.86% of all pituitary tumors operated at our
institute over a 9-year period
Solitary cerebellous metastasis after prolonged remission in a case of uterine cervical adenocarcinoma
Intracranial metastasis of a uterine cervical carcinoma is a very rare occurrence. These metastases are characteristically multiple, supra-tentorial, associated with multiple systemic dissemination, usually occur relatively late in the course of the disease, and are most often seen in squamous carcinomas. We present an unusual case which defied these characteristics. This patient was in long-term remission (11 years), presented with a solitary cerebellous metastases, had no evidence of other systemic spread, and the pathology was an adenocarcinoma. We present this rare case with interesting clinical ramifications. This is probably the longest duration of remission prior to the metastasis in the published literature
Inflammatory myofibroblastic tumor parieto-occipital bone
Inflammatory myofibroblastic tumor is a diverse group of lesions first described in lung and later on reported in various sites like stomach, bowel, spleen, bone. We report a case of inflammatory myofibroblastic tumor in a 30-year-old male who presented with a slowly progressive scalp swelling of two-year duration. Magnetic resonance imaging showed an intradiploic well enhancing lesion in parietal and occipital bone, isointense on T1 weighted images and hypo intense on T2 weighted images with dural enhancement. On histopathological examination, the lesion was composed of variable admixture of spindle cells with eosinophilic cytoplasm and inflammatory cells comprising of plasma cells and lymphocytes. The lesion was infiltrating the underlying dura. The spindle cells showed strong positivity for smooth muscle actin on immunohistochemistry. A final histopathologic diagnosis of inflammatory myofibroblastic tumor was rendered
Myriad of MR imaging phenotypes of primary central nervous system lymphoma in a cohort of immunocompetent Indian patient population
PCNSL (primary central nervous system lymphoma) is a chemosensitive and radiosensitive tumor, and early diagnosis has a significant impact on management. Unlike many other brain tumors, radical surgical excision of PCNSLs is not indicated because these lesions are highly infiltrative and even partial resection leads to a bad prognosis. The goal of this study is to highlight the unusual radiological presentation of PCNSLs and increase the awareness, familiarity, and global database of our observations that pose a challenge on management