アメリカ文学史へのアプローチ : 作品100選

第1章　植民地時代と清教徒の社会……………………1第2章　アメリカの独立と建国の父祖たち……………7第3章　国民文学の成立…………………………………15第4章　アメリカン・ルネッサンス……………………21第5章　4人の代表的詩人たち…………………………29第6章　南北戦争と文学…………………………………39第7章　リアリズム………………………………………45第8章　自然主義…………………………………………53第9章　中西部の作家たち………………………………61第10章　失われた世代の作家たちとモダニズム……67第11章　南部の作家たち………………………………75第12章　1930年代の小説………………………………81第13章　第二次世界大戦後の文学……………………87第14章　ポストモダニズム……………………………95第15章　ユダヤ系作家たち……………………………105第16章　アフロ・アメリカン文学……………………113第17章　女性作家たち…………………………………123第18章　ネイテイヴ・アメリカン文学………………139第19章　アメリカ演劇…………………………………143第20章　現代アメリカ詩………………………………15

Parallel and Distributed Trajectory Generation of Redundant Manipulators through Cooperation and Competition among Subsystems

The autonomous distributed control (ADC) is oneof the most attractive approaches for more versatile and autonomousrobot systems. This paper proposes a parallel anddistributed trajectory generation method for redundant manipulatorsthrough cooperative and competitive interactions amongsubsystems composing the ADC that is based on a concept ofvirtual arms. The virtual arm has the same kinematic structureas the manipulator except that its end-point is located on a jointor link of the manipulator. Then the redundant manipulatorcan be represented by a set of the virtual arms. In this paper,trajectory generation and point-to-point control of the redundantmanipulator are discussed, and it is shown that the kinematicredundancy of the manipulator can be utilized positively in thegenerated trajectories by using the virtual arms

Instantaneous inverse kinematic solution for redundant manipulators based on virtual arms and its application to winding control

The present paper proposes an instantaneous inverse kinematic solution for redundant manipulators based on virtual arms. The virtual arm has the same kinematic structure as the manipulator except that its end-point is located on the joint or link of the manipulator. When the appropriate virtual arms are used, the configuration of the manipulator can be represented by a set of end-points of the virtual arms. First of all, this paper formalizes the kinematics of virtual arms and derives instantaneous inverse kinematics. Then, the method is applied to winding control for hyper-redundant manipulators. The winding control presented here is divided into two steps: 1)planning desired positions for virtual end-points, 2)integrating them into the joint trajectory of the manipulator. The desired positions of each virtual arm can be computed in a parallel and distributed way and it is not necessary to consider joint space of the manipulator. Finally computer simulations show that the winding control for a hyper-redundant manipulator can be performed in 3D-space

Periductal Induction of High Endothelial Venule-Like Vessels in Type 1 Autoimmune Pancreatitis

信州大学博士（医学）・学位論文・平成24年3月31日授与（甲第946号）・丸山 雅史This is a non-final version of an article published in final form in PANCREAS. 42(1):53-59 (2013).Objectives: Type 1 autoimmune pancreatitis (AIP) is histologically characterized by dense lymphoplasmacytic infiltration and marked storiform fibrosis, manifestations associated with pancreatic ducts. Such periductal lymphocyte recruitment is thought to be elicited by dysregulation of mechanisms governing physiological lymphocyte homing. The present study was undertaken to determine whether vascular addressins including peripheral lymph node addressin and mucosal addressin cell adhesion molecule 1 (MAdCAM-1) play a role in type 1 AIP histogenesis. Methods: Tissue sections of type 1 AIP and tumor-associated non-AIP chronic pancreatitis, as well as normal pancreas, were subjected to immunohistochemical analysis using vascular addressin-related antibodies. Results: The number of periductal mouse endothelial cell antigen 79-positive high endothelial venule (HEV)-like vessels was increased in type 1 AIP relative to that seen in non-AIP chronic pancreatitis, whereas the number of MAdCAM-1-positive HEV-like vessels did not differ between the 2 conditions. Mouse endothelial cell antigen 79 antigens are expressed on duct-forming epithelial cells not only in pancreas but also in salivary glands, which often harbor extrapancreatic lesions in type 1 AIP. Conclusions: Type 1 AIP can be characterized by periductal induction of MECA-79-positive HEV-like vessels. MECA-79-positive 6-sulfo sialyl Lewis X-related carbohydrate antigens expressed on duct-forming epithelial cells could be associated with type 1 AIP pathogenesis.ArticlePANCREAS. 42(1):53-59 (2013)journal articl

Identification of three Early Pleistocene tephras in and around the west part of the Musashino Upland, Tokyo, Northeast Japan

In and around the west part of the Musashino Upland, southwest of the Kanto Tectonic Basin, Ob4b-4 (1.62 Ma), Ob4b-1 (1.63 Ma), and Ob3 (1.71-1.78 Ma) tephras in the Kazusa Group, early Quaternary strata, were identified by using characteristic properties such as chemical composition of volcanic glass shards and titanomagnetite, and refractive indices of glass shards, hornblende, cummingtonite, and orthopyroxene. Changes in altitudes of Ob4b-1 identified in four cores and at three outcrops together with those by previous studies indicate geological structure of the Kazusa Group, revealing a gentle northeastward sloping with a gradient of 15/1000 and a prominent discontinuity of the strata along the Tachikawa Fault Zone

Innovative Treatment of a Fetal Lung Mass Model Using High-intensity Focused Ultrasound (HIFU)

Current therapy for space-occupying fetal lung mass lesions (fetal pulmonary lobectomy) is invasive and technically demanding. Accordingly, new therapeutic procedures are required which are much less invasive and more efficient. The purpose of this study was to investigate the feasibility of high-intensity focused ultrasound (HIFU) as a new therapeutic modality for fetal lung mass lesions, using an experimental animal model. We created a solid fetal lung model by differential lung ventilation using anesthetized adult rabbits. In this model, experimental animals with a unilateral independent (fluid-filled) lung were maintained by single lung ventilation of the other dependent lung. Within the independent lung, target blood vessels depicted by color flow Doppler were repeatedly irradiated with HIFU energy beams (n=19). Occlusion of these blood vessels in vivo was confirmed by evaluation of the flow using color flow Doppler. After the procedure, the animals were sacrificed and their harvested lungs were assessed grossly and microscopically. Pulmonary blood vessels (artery and/or vein) were effectively occluded with 2 to 5 cycles of HIFU energy delivery (10.5 seconds each) with a success rate of 62.5% (arteries) and 72.7% (veins). No clear changes including tissue perforations were observed grossly on the surface of the lungs. Ultrasound-guided HIFU energy delivery seems promising for occlusion of the pulmonary blood vessels within a fluid-filled independent lung (fetal lung model). Thus in the future, HIFU irradiation could be used as a less invasive technique to occlude the feeding vessels of fetal lung mass lesions in utero

The Possibility of the Curriculum Designs implemented by the Social Studies Teachers : A Case Study on the Development and Application of the History Resource Book

The purposes of this paper are to describe the curriculum designs implemented by the four Social Studies teachers in the same school but from the different background, and to explain the reasons why they showed the various designs, even though they are requested to apply the common history resource book into the regular classes. The present results suggested that the ideas and aims concerning the subject which each Social Studies teacher conceived had much influences on the differentiation of their practices, but their experiences of the professional development on the curriculum and instruction, the orientation of the school management, and the leadership demonstrated by the principal had more influences on the assimilation of their attitude toward the class improvement, particularly in the case of sampled teachers and school

Self-Contained Induction of Neurons from Human Embryonic Stem Cells

BACKGROUND: Neurons and glial cells can be efficiently induced from mouse embryonic stem (ES) cells in a conditioned medium collected from rat primary-cultured astrocytes (P-ACM). However, the use of rodent primary cells for clinical applications may be hampered by limited supply and risk of contamination with xeno-proteins. METHODOLOGY/PRINCIPAL FINDINGS: We have developed an alternative method for unimpeded production of human neurons under xeno-free conditions. Initially, neural stem cells in sphere-like clusters were induced from human ES (hES) cells after being cultured in P-ACM under free-floating conditions. The resultant neural stem cells could circumferentially proliferate under subsequent adhesive culture, and selectively differentiate into neurons or astrocytes by changing the medium to P-ACM or G5, respectively. These hES cell-derived neurons and astrocytes could procure functions similar to those of primary cells. Interestingly, a conditioned medium obtained from the hES cell-derived astrocytes (ES-ACM) could successfully be used to substitute P-ACM for induction of neurons. Neurons made by this method could survive in mice brain after xeno-transplantation. CONCLUSION/SIGNIFICANCE: By inducing astrocytes from hES cells in a chemically defined medium, we could produce human neurons without the use of P-ACM. This self-serving method provides an unlimited source of human neural cells and may facilitate clinical applications of hES cells for neurological diseases