Suzaku Observations of the Great Annihilator and the Surrounding Diffuse Emissions

We report the Suzaku observation of 1E 1740.7-2942, a black hole candidate called the "Great Annihilator" (GA). The high-quality spectrum of Suzaku provides the severest constraints on the parameters of the GA. Two clumpy structures are found around the GA in the line images of FeI Kalpha at 6.4 keV and SXV Kalpha at 2.45 keV. One clump named M359.23-0.04 exhibits the 6.4-keV line with an equivalent width of ~ 1.2 keV, and is associated with a molecular cloud in the radio CS(J=1-0) map. Thus the 6.4-keV line from M359.23-0.04 is likely due to X-ray fluorescence irradiated by an external X-ray source. The irradiating X-rays would be either the past flare of Sagittarius A* or the bright nearby source, the GA. The other clump named G359.12-0.05 is associated with the radio supernova remnant candidate G359.07-0.02. We therefore propose that G359.12-0.05 is an X-ray counterpart of G359.07-0.02. G359.12-0.05 has a thin thermal plasma spectrum with a temperature of kT ~ 0.9 keV. The plasma parameters of G359.12-0.05 are consistent with those of a single supernova remnant in the Galactic center region.Comment: 10 pages, 8 figures, accepted for publication in PASJ (Vol.62, No.4

Forming the Russian Fascist Party in Harbin 1925-1933

奥村哲教授・木村誠教授記念論文

Factors Affecting Customer’s Perception of Service Quality: Comparing Differences among Countries - Case study: Beauty salons in Bandung and Tokyo

This paper examines a holistic study of analyzing several factors affecting service quality andtheir correlation with characteristic of customers based on value and life style. Furthermore,customer’s perception of service quality can be drawn from those relationships. Exploratoryfactor analysis and quantitative analysis is employed with case study of beauty salon serviceat Bandung and Tokyo. The results indicate how the quality of services is perceived differentlyby customers who have different value and life style, and also describe significant relationshipbetween value and life style with the affecting factors of service quality.Key words : service quality, value and life style, customer perception, beauty salon

Extremely Strong ^{13}CO J=3-2 Line in the "Water Fountain" IRAS 16342-3814: Evidence for the Hot-Bottom Burning

We observed four "water fountain" sources in the CO J=3-2 line emission with the Atacama Submillimeter Telescope Experiment (ASTE) 10 m telescope in 2010-2011. The water fountain sources are evolved stars that form high-velocity collimated jets traced by water maser emission. The CO line was detected only from IRAS 16342-3814. The present work confirmed that the ^{12}CO to ^{13}CO line intensity ratio is ~1.5 at the systemic velocity. We discuss the origins of the very low ^{12}CO to ^{13}CO intensity ratio, as possible evidence for the "hot-bottom burning" in an oxygen-rich star, and the CO intensity variation in IRAS 16342-3814.Comment: 10 pages, 3 figures, accepted for publication to the Publications of the Astronomical Society of Japan, Vol. 64, No.

Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization

<p>Abstract</p> <p>Background</p> <p>It has been postulated that ionizing radiation induces breast cancers among atomic bomb (A-bomb) survivors. We have reported a higher incidence of <it>HER2 </it>and <it>C-MYC </it>oncogene amplification in breast cancers from A-bomb survivors. The purpose of this study was to clarify the effect of A-bomb radiation exposure on genomic instability (GIN), which is an important hallmark of carcinogenesis, in archival formalin-fixed paraffin-embedded (FFPE) tissues of breast cancer by using microarray-comparative genomic hybridization (aCGH).</p> <p>Methods</p> <p>Tumor DNA was extracted from FFPE tissues of invasive ductal cancers from 15 survivors who were exposed at 1.5 km or less from the hypocenter and 13 calendar year-matched non-exposed patients followed by aCGH analysis using a high-density oligonucleotide microarray. The total length of copy number aberrations (CNA) was used as an indicator of GIN, and correlation with clinicopathological factors were statistically tested.</p> <p>Results</p> <p>The mean of the derivative log ratio spread (DLRSpread), which estimates the noise by calculating the spread of log ratio differences between consecutive probes for all chromosomes, was 0.54 (range, 0.26 to 1.05). The concordance of results between aCGH and fluorescence in situ hybridization (FISH) for <it>HER2 </it>gene amplification was 88%. The incidence of <it>HER2 </it>amplification and histological grade was significantly higher in the A-bomb survivors than control group (P = 0.04, respectively). The total length of CNA tended to be larger in the A-bomb survivors (P = 0.15). Correlation analysis of CNA and clinicopathological factors revealed that DLRSpread was negatively correlated with that significantly (P = 0.034, r = -0.40). Multivariate analysis with covariance revealed that the exposure to A-bomb was a significant (P = 0.005) independent factor which was associated with larger total length of CNA of breast cancers.</p> <p>Conclusions</p> <p>Thus, archival FFPE tissues from A-bomb survivors are useful for genome-wide aCGH analysis. Our results suggested that A-bomb radiation may affect the increased amount of CNA as a hallmark of GIN and, subsequently, be associated with a higher histologic grade in breast cancer found in A-bomb survivors.</p