Evaluation of superconductor assisted machining (SUAM) with superconducting coated conductors using the finite element method

In the present study, we numerically calculated the magnetic levitation force for superconductor assisted machining (SUAM) using the finite element method. Although we usually use bulk superconductors for magnetic levitation in SUAM, we herein considered magnetic levitation using superconductor-coated conductors. We were able to explain the experimental results on the forces of the coated conductors as well as bulk theoretically. For both bulk and coated conductor, the repulsive force was found to increase as the distance from the permanent magnet became shorter. For the coated materials, both the repulsive and attractive forces were lower than in the case of bulk superconductors. This is because the volume of superconducting material was smaller than in the case of bulk superconductors, since the overall size of both materials was the same. However, we believe that greater forces can be obtained by increasing the number of coated conductors.32nd International Symposium on Superconductivity (ISS2019), 3-5 December, 2019, Kyoto, Japa

Application of COMPOCHIP Microarray to Investigate the Bacterial Communities of Different Composts

A microarray spotted with 369 different 16S rRNA gene probes specific to microorganisms involved in the degradation process of organic waste during composting was developed. The microarray was tested with pure cultures, and of the 30,258 individual probe-target hybridization reactions performed, there were only 188 false positive (0.62%) and 22 false negative signals (0.07%). Labeled target DNA was prepared by polymerase chain reaction amplification of 16S rRNA genes using a Cy5-labeled universal bacterial forward primer and a universal reverse primer. The COMPOCHIP microarray was applied to three different compost types (green compost, manure mix compost, and anaerobic digestate compost) of different maturity (2, 8, and 16 weeks), and differences in the microorganisms in the three compost types and maturity stages were observed. Multivariate analysis showed that the bacterial composition of the three composts was different at the beginning of the composting process and became more similar upon maturation. Certain probes (targeting Sphingobacterium, Actinomyces, Xylella/Xanthomonas/ Stenotrophomonas, Microbacterium, Verrucomicrobia, Planctomycetes, Low G + C and Alphaproteobacteria) were more influential in discriminating between different composts. Results from denaturing gradient gel electrophoresis supported those of microarray analysis. This study showed that the COMPOCHIP array is a suitable tool to study bacterial communities in composts

Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease

BACKGROUND: The precise timing of the angiogenic switch and the role of angiogenesis in the development of breast malignancy is currently unknown. METHODS: Therefore, the expression of CD31 (pan endothelial cells (ECs)), endoglin (actively proliferating ECs), hypoxia-inducible factor-1 (HIF-1alpha), vascular endothelial growth factor-A (VEGF) and tissue factor (TF) were quantified in 140 surgical specimens comprising normal human breast, benign and pre-malignant hyperplastic tissue, in situ and invasive breast cancer specimens. RESULTS: Significant increases in angiogenesis (microvessel density) were observed between normal and benign hyperplastic breast tissue (P<0.005), and between in situ and invasive carcinomas (P<0.0005). In addition, significant increases in proliferating ECs were observed in benign hyperplastic breast compared with normal breast (P<0.05) cancers and in invasive compared with in situ cancers (P<0.005). Hypoxia-inducible factor-1alpha, VEGF and TF expression were significantly associated with increases in both angiogenesis and proliferating ECs (P<0.05). Moreover, HIF-1alpha was expressed by 60-75% of the hyperplastic lesions, and a significant association was observed between VEGF and TF in ECs (P<0.005) and invasive tumour cells (P<0.01). CONCLUSIONS: These findings are the first to suggest that the angiogenic switch, associated with increases in HIF-1alpha, VEGF and TF expression, occurs at the onset of hyperplasia in the mammary duct, although the greatest increase in angiogenesis occurs with the development of invasion

A unified latent variable model for contrastive opinion mining

There are large and growing textual corpora in which people express contrastive opinions about the same topic. This has led to an increasing number of studies about contrastive opinion mining. However, there are several notable issues with the existing studies. They mostly focus on mining contrastive opinions from multiple data collections, which need to be separated into their respective collections beforehand. In addition, existing models are opaque in terms of the relationship between topics that are extracted and the sentences in the corpus which express the topics; this opacity does not help us understand the opinions expressed in the corpus. Finally, contrastive opinion is mostly analysed qualitatively rather than quantitatively. This paper addresses these matters and proposes a novel unified latent variable model (contraLDA), which: mines contrastive opinions from both single and multiple data collections, extracts the sentences that project the contrastive opinion, and measures the strength of opinion contrastiveness towards the extracted topics. Experimental results show the effectiveness of our model in mining contrasted opinions, which outperformed our baselines in extracting coherent and informative sentiment-bearing topics. We further show the accuracy of our model in classifying topics and sentiments of textual data, and we compared our results to five strong baselines