The impact of C‐reactive protein‐albumin‐lymphocyte (CALLY) index on the prognosis of patients with distal cholangiocarcinoma following pancreaticoduodenectomy

Abstract Aim The C‐reactive protein (CRP)‐albumin‐lymphocyte (CALLY) index is a novel inflammation‐based biomarker, which has been associated with long‐term outcomes in patients with hepatocellular carcinoma. We aimed to investigate whether the CALLY index can predict the prognosis for distal cholangiocarcinoma after pancreaticoduodenectomy. Methods The study comprised 143 patients who had undergone primary pancreaticoduodenectomy for distal cholangiocarcinoma between 2002 to 2019. The CALLY index was defined as (albumin × lymphocyte)/ (CRP × 104). We investigated the association of CALLY index with disease‐free survival and overall survival by univariate and multivariate analyses. Results Eighty‐seven (61%) patients had a preoperative CALLY index <3.5. In multivariate analysis, obstructive jaundice drainage (P < .01), poorly differentiated tumor (P < .01), and CALLY index<3.5 (P = .02) were independent predictors of disease‐free survival, while obstructive jaundice drainage (P < .01), poorly differentiated tumor (P < .01), and CALLY index <3.5 (P = .02) were independent predictors of overall survival. Conclusion The CALLY index may be an independent and significant indicator of poor long‐term outcomes in patients with distal cholangiocarcinoma after pancreaticoduodenectomy, suggesting the importance of comprehensive assessment for inflammatory status

Construction of a Forward Electro-magnetic Calorimeter SCISSORS III(I. Nuclear Physics)

A new electro-magnetic calorimeter complex FOREST with a solid angle of about 4π in total is under construction. It consists of three calorimeters: a forward one with CsI crystals, a middle one with lead scintillating fiber modules, and a backward one with lead glass Cerenkov counters. Recently, the forward calorimeter SCISSORS III takes shape

Photoproduction of η-mesons off C and Cu Nuclei for Photon Energies below 1.1 GeV(I. Nuclear Physics)

The η-meson photoproduction cross sections have been measured on C and Cu targets for photon energies between 600 and 1100MeV to investigate the behavior of the S_11 (1535) resonance in a nucleus. The excitation functions of the cross section as well as angular and momentum distributions of η-mesons are in quantitative agreement with Quantum Molecular Dynamics (QMD) model calculations, in which the η-meson emission processes other than the S_11 (1535) resonance are also incorporated as proposed in the η-MAID model. It is shown that the excitation of the D_15 (1675) resonance might play an important role for E_γ>900MeV

Double Pion Photoproduction on Deuteron(I. Nuclear Physics)

Exclusive cross sections for double-pion photoproductions on proton and deuteron were measured in an energy range from 0.8 to 1.1GeV using tagged photons at Laboratory of Nuclear Science, Tohoku University. We employed the Neutral Kaon Spectrometer (NKS) to detect two pions in the final state, and deduced the cross section for the π^+π^- photoproduction on the "free" and "bound" proton. We have discriminated between the quasi-free and non-quasi-free process applying the kinematical cut on the missing momentum. We found that the total cross section for the γ"p"→pπ^+π^- reaction was about 60% of that for the "free" proton, and this is consistent with the previously obtained data. The one of the dominant part of the non-quasi-free process was found to be the double Δ production. Its cross section is smaller than the previous investigations

Photoproduction of Neutral Kaons on Liquid Deuterium Target(I. Nuclear Physics)

We have performed the experiment of K^0 photoproduction on the liquid deuterium target with Neutral Kaon Spectrometer (NKS) at LNS-Tohoku. The K^0s were measured via K^0_S→π^+π^- decay channel in the threshold region. The momentum spectra of K^0 photoproduction cross sections were derived and compared with the calculations using representative models