8 research outputs found

    Thermodynamics of Nucleation of Silicon Carbide Nanocrystals during Carbonization of Porous Silicon

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    The formation of SiC nanocrystals of the cubic modification in the process of high-temperature carbonization of porous silicon has been analyzed. It has been shown that the surface energy of silicon nanoparticles and quantum filaments is released in the process of annealing and carbonization. The Monte Carlo simulation has shown that the released energy makes it possible to overcome the nucleation barrier and to form SiC nanocrystals

    Microelectromechanical Systems of the Impulse Betavoltaics Element for Electric Power of Biosensors

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    In the paper we carry out the calculation mechanical properties and intracellular pressure of erythro-cytes by finite element method and comparison of these data to the experimental data obtained using atomic force microscopy. The paper proposes a model of the erythrocyte representing the erythrocyte as a homogeneous elastic body with the elasticity depending on the distance to the center of the erythrocyte. The model is based on data from atomic force microscopy obtained by various authors, in particular the da-ta on rigidity of the membrane, which depends on the position of the measuring point on the surface. The good agreement between calculated and experimental data confirms the consistency of the model and al-lows us to conclude that the morphology of the erythrocyte is largely determined by the elastic properties of the membrane and intercellular pressure

    Biosensor Scheme for the Determination of Intracellular Pressure of Erythrocyte

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    The paper presents a scheme of the biosensor for determining the intracellular pressure of erythrocytes. The possibility of measuring of the volume and area of the erythrocyte is provided in a biosensor to determine the value intracellular pressure. In MEMS this creates flow that enters into Coulter capacitive sensor through the rate control system and then in the system of signal transmitting. The definition of erythrocyte volume and calculation of intracellular pressure occur in the computer system

    Calculation of Intracellular Pressure of Red Blood Cells at Jaundice According to Atomic Force Microscopy Data

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    The present work is devoted to the analysis of three-dimensional data of atomic force microscopy for research of the morphology of red blood cells. In this paper we built a biomechanical model of the erythrocyte, which allowed calculating the intracellular pressure of erythrocyte based on data of atomic force microscopy. As a result, we obtained the dependence intracellular pressure on the morphology of red blood cell. We have proposed a method of estimating of intracellular pressure of erythrocytes based on numerical modeling and data of atomic force microscopy of erythrocytes scan, which involves a comparison of the experimental data with the results of numerical calculation. The method is applied to the data of atomic force microscopy of erythrocytes of experimental animals - dwarf domestic pigs with different degrees of obstructive jaundice and normal. It is shown that with increasing severity of the disease and the concentration of bilirubin in the blood there is an infringement erythrocyte membranes, by an average increasing their volume and intracellular pressure

    Calculation of Intracellular Pressure of Red Blood Cells at Jaundice According to Atomic Force Microscopy Data

    Get PDF
    The present work is devoted to the analysis of three-dimensional data of atomic force microscopy for research of the morphology of red blood cells. In this paper we built a biomechanical model of the erythrocyte, which allowed calculating the intracellular pressure of erythrocyte based on data of atomic force microscopy. As a result, we obtained the dependence intracellular pressure on the morphology of red blood cell. We have proposed a method of estimating of intracellular pressure of erythrocytes based on numerical modeling and data of atomic force microscopy of erythrocytes scan, which involves a comparison of the experimental data with the results of numerical calculation. The method is applied to the data of atomic force microscopy of erythrocytes of experimental animals - dwarf domestic pigs with different degrees of obstructive jaundice and normal. It is shown that with increasing severity of the disease and the concentration of bilirubin in the blood there is an infringement erythrocyte membranes, by an average increasing their volume and intracellular pressure

    Simulation of Mechanical Properties and Intracellular Pressure of Erythrocyte According to Atomic Force Microscopy

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    In the paper we carry out the calculation mechanical properties and intracellular pressure of erythrocytes by finite element method and comparison of these data to the experimental data obtained using atomic force microscopy. The paper proposes a model of the erythrocyte representing the erythrocyte as a homogeneous elastic body with the elasticity depending on the distance to the center of the erythrocyte. The model is based on data from atomic force microscopy obtained by various authors, in particular the data on rigidity of the membrane, which depends on the position of the measuring point on the surface. The good agreement between calculated and experimental data confirms the consistency of the model and allows us to conclude that the morphology of the erythrocyte is largely determined by the elastic properties of the membrane and intercellular pressure

    Simulation of Mechanical Properties and Intracellular Pressure of Erythrocyte According to Atomic Force Microscopy

    Get PDF
    In the paper we carry out the calculation mechanical properties and intracellular pressure of erythrocytes by finite element method and comparison of these data to the experimental data obtained using atomic force microscopy. The paper proposes a model of the erythrocyte representing the erythrocyte as a homogeneous elastic body with the elasticity depending on the distance to the center of the erythrocyte. The model is based on data from atomic force microscopy obtained by various authors, in particular the data on rigidity of the membrane, which depends on the position of the measuring point on the surface. The good agreement between calculated and experimental data confirms the consistency of the model and allows us to conclude that the morphology of the erythrocyte is largely determined by the elastic properties of the membrane and intercellular pressure

    Biosensor Scheme for the Determination of Intracellular Pressure of Erythrocyte

    Get PDF
    The paper presents a scheme of the biosensor for determining the intracellular pressure of erythrocytes. The possibility of measuring of the volume and area of the erythrocyte is provided in a biosensor to determine the value intracellular pressure. In MEMS this creates flow that enters into Coulter capacitive sensor through the rate control system and then in the system of signal transmitting. The definition of erythrocyte volume and calculation of intracellular pressure occur in the computer system
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