Mucosal Immunity and Candida albicans Infection

Interactions between mucosal surfaces and microbial microbiota are key to host defense, health, and disease. These surfaces are exposed to high numbers of microbes and must be capable of distinguishing between those that are beneficial or avirulent and those that will invade and cause disease. Our understanding of the mechanisms involved in these discriminatory processes has recently begun to expand as new studies bring to light the importance of epithelial cells and novel immune cell subsets such as Th17 T cells in these processes. Elucidating how these mechanisms function will improve our understanding of many diverse diseases and improve our ability to treat patients suffering from these conditions. In our voyage to discover these mechanisms, mucosal interactions with opportunistic commensal organisms such as the fungus Candida albicans provide insights that are invaluable. Here, we review current knowledge of the interactions between C. albicans and epithelial surfaces and how this may shape our understanding of microbial-mucosal interactions

The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage

Funding: Our own work was funded by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (102549/Z/13/Z), a Wellcome Trust ISSF (RG12723-14), the MRC and University of Aberdeen (MR/N006364/1) (DW); Medical Research Council (MR/J008303/1, MR/M011372/1), Biotechnology & Biological Sciences Research Council (BB/J015261/1), FP7-PEOPLE-2013-Initial Training Network (606786) (JRN); Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology (097377/Z/11/Z) (JRN and DW); Deutsche Forschungsgemeinschaft CRC/TR124 FungiNet Project C1 and SPP 1580 (Hu 528/17-1) and CSCC, German Federal Ministry of Education and Health [BMBF] 01EO1002 (BH). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

Bronisława Dymara – charyzmatyczny pedagog, „człowiek ducha”, naukowy przewodnik

The article introduces the figure of Bronisława Dymara, PhD, a long‑term teacher and academic at the University of Silesia. Bronisława Dymara was a person whose life was rife with difficulty; nevertheless, she persisted as a passionate teacher and instructor. She is the author of a particularly famous and well‑regarded among teachers book series entitled From Teachers for Teachers. The series comprises over 30 volumes under a collective title A Child in the World… Her research and humanist attitude was and remain an inspiration for people making their first steps in the world of academia