Effects of aminoperimidine on electrolyte transport across amphibian skin

The effect of aminoperimidine (AP)on transepithelial Na+ transport and Cl- conductance (G(Cl)) of isolated amphibian skin (Bufo viridis and Rana esculenta) was analyzed using transepithelial and intracellular electrophysiological techniques. AP, applied at concentrations between 30 and 100 mu M from the mucosal side, stimulated Na+ transport rapidly and reversibly by more than 30% of the control value due to an increase in apical membrane Na+ permeability. Influence of AP on basolateral membrane conductance and effective driving force for Na+ were negligible. Voltage-activated G(Cl) of toad skin, but not the resting, deactivated conductance, as well as spontaneously high G(Cl) in frog skin was rapidly inhibited by AP in a concentration-dependent manner. The half-maximal inhibitory concentration of 20 mu M is the highest hithero reported inhibitory power for G(Cl) in amphibian skin. The effect of AP on G(Cl) was slowly and incompletely reversible even after brief exposure to the agent. Serosal application of AP had similar, albeit delayed effects on both Nai and Cl- transport. AP did not interfere with the Cl- pathway after it was opened by 100-300 mu M CPT-cAMP, a membrane-permeable, nonhydrolyzed analogue of cAMP. Inhibition of the voltage-activated G(Cl) by AP was attenuated or missing when AP was applied during voltage perturbation to serosa-positive potentials. Since AP is positively charged at physiological pH, it suggests that the affected site is located inside the Cl- pathway at a certain distance from the external surface. AP affects then the Na+ and Cl- transport pathways independent of each other. The nature of chemical interference with AP, which is responsible for the influence on the transport of Na+ and Cl-, remains to be elucidated

Unidirectional terahertz light absorption in the pyroelectric ferrimagnet CaBaCo4O7

Spin excitations were studied by absorption spectroscopy in CaBaCo4O7 which is a type-I multiferroic compound with the largest magnetic-order induced ferroelectric polarization ({\Delta}P=17mC/m2) reported, so far. We observed two optical magnon branches: a solely electric dipole allowed one and a mixed magnetoelectric resonance. The entangled magnetization and polarization dynamics of the magnetoelectric resonance gives rise to unidirectional light absorption, i.e. that magnon mode absorbs the electromagnetic radiation for one propagation direction but not for the opposite direction. Our systematic study of the magnetic field and temperature dependence of magnon modes provides information about the energies and symmetries of spin excitations, which is required to develop a microscopic spin model of CaBaCo4O7.Comment: 5 pages, 4 figure

Presence of Many Stable Nonhomogeneous States in an Inertial Car-Following Model

A new single lane car following model of traffic flow is presented. The model is inertial and free of collisions. It demonstrates experimentally observed features of traffic flow such as the existence of three regimes: free, fluctuative (synchronized) and congested (jammed) flow; bistability of free and fluctuative states in a certain range of densities, which causes the hysteresis in transitions between these states; jumps in the density-flux plane in the fluctuative regime and gradual spatial transition from synchronized to free flow. Our model suggests that in the fluctuative regime there exist many stable states with different wavelengths, and that the velocity fluctuations in the congested flow regime decay approximately according to a power law in time.Comment: 4 pages, 4 figure

Two-dimensional cellular automaton model of traffic flow with open boundaries

A two-dimensional cellular automaton model of traffic flow with open boundaries are investigated by computer simulations. The outflow of cars from the system and the average velocity are investigated. The time sequences of the outflow and average velocity have flicker noises in a jamming phase. The low density behavior are discussed with simple jam-free approximation.Comment: 14 pages, Phys. Rev. E in press, PostScript figures available at ftp://hirose.ai.is.saga-u.ac.jp/pub/documents/papers/1996/2DTR/ OpenBoundaries/Figs.tar.g

Photoassociative spectroscopy at long range in ultracold strontium

We report photoassociative spectroscopy of $^{88}$Sr$_2$ in a magneto-optical trap operating on the ${^1S_0}\to{^3P_1}$ intercombination line at 689 nm. Photoassociative transitions are driven with a laser red-detuned by 600-2400 MHz from the ${^1S_0}\to{^1P_1}$ atomic resonance at 461 nm. Photoassociation takes place at extremely large internuclear separation, and the photoassociative spectrum is strongly affected by relativistic retardation. A fit of the transition frequencies determines the ${^1P_1}$ atomic lifetime ($\tau=5.22 \pm 0.03$ ns) and resolves a discrepancy between experiment and recent theoretical calculations.Comment: 4 pages, 4 figures, submitte

Fundamentals of Traffic Flow

From single vehicle data a number of new empirical results concerning the density-dependence of the velocity distribution and its moments as well as the characteristics of their temporal fluctuations have been determined. These are utilized for the specification of some fundamental relations of traffic flow and compared with existing traffic theories.Comment: For related work see http://www.theo2.physik.uni-stuttgart.de/helbing.htm