Generation of squeezed light with monolithic optical parametric oscillator: Simultaneous achievement of phase matching and cavity resonance by temperature control

We generate squeezed state of light at 860 nm with a monolithic optical parametric oscillator. The optical parametric oscillator consists of a periodically poled KTiOPO_4 crystal, both ends of which are spherically polished and mirror-coated. We achieve both phase matching and cavity resonance by controlling only the temperature of the crystal. We observe up to -8.0 dB of squeezing with the bandwidth of 142 MHz. Our technique makes it possible to drive many monolithic cavities simultaneously by a single laser. Hence our monolithic optical parametric oscillator is quite suitable to continuous-variable quantum information experiments where we need a large number of highly squeezed light beams.Comment: 8 pages, 4 figure

Medical Treatment for Burn Patients with Eating Disorders: A Case Report

There have been many cases of burn patients who also suffer from psychiatric problems, including eating disorders. We present a case of a 38-year-old female with an eating disorder and depression who became light-headed and fell, spilling boiling water from a kettle on herself at home sustaining partial thickness and full thickness burns over 5% of her total body surface area: left buttock and right thigh and calf. Eating disorders (in the present case, anorexia nervosa) cause emaciation and malnutrition, and consent for hospitalization from the patient and/or family is often difficult. During the medical treatment of burns for these patients, consideration not only of physical symptoms caused by malnutrition but also the psychiatric issues is required. Therefore, multifaceted and complex care must be given to burn patients with eating disorders

Supravalvular thrombus after pulmonary artery banding and fontan procedure evaluated by multidetector-row computed tomography

SummaryThe mechanisms responsible for thromboembolic events in children with congenital heart disease have not yet been fully elucidated. Furthermore, establishment of long-term anticoagulation therapy in Fontan patients remains controversial. Here, we report the case of a 9-year-old boy who presented with hemiparesis due to a thromboembolic stroke; the boy had previously undergone staged pulmonary artery banding and Fontan procedure. Cardiac multidetector-row computed tomography (MDCT) clearly showed the supravalvular thrombus at the roofed (blind) pulmonary valve and circulatory stasis, which could be considered a possible source of the thrombus. Follow-up CT examination showed that the thrombus disappeared, but the circulatory stasis remained. Therefore, because the risk of thrombus formation was not eliminated, anticoagulation therapy was continued for the patient. Our case indicates the possible application of cardiac MDCT for providing insight into the hemodynamic mechanisms responsible for the thromboembolic events in children with congenital heart disease

Real-Time Visualization of HIV-1 GAG Trafficking in Infected Macrophages

HIV-1 particle production is driven by the Gag precursor protein Pr55Gag. Despite significant progress in defining both the viral and cellular determinants of HIV-1 assembly and release, the trafficking pathway used by Gag to reach its site of assembly in the infected cell remains to be elucidated. The Gag trafficking itinerary in primary monocyte-derived macrophages is especially poorly understood. To define the site of assembly and characterize the Gag trafficking pathway in this physiologically relevant cell type, we have made use of the biarsenical-tetracysteine system. A small tetracysteine tag was introduced near the C-terminus of the matrix domain of Gag. The insertion of the tag at this position did not interfere with Gag trafficking, virus assembly or release, particle infectivity, or the kinetics of virus replication. By using this in vivo detection system to visualize Gag trafficking in living macrophages, Gag was observed to accumulate both at the plasma membrane and in an apparently internal compartment that bears markers characteristic of late endosomes or multivesicular bodies. Significantly, the internal Gag rapidly translocated to the junction between the infected macrophages and uninfected T cells following macrophage/T-cell synapse formation. These data indicate that a population of Gag in infected macrophages remains sequestered internally and is presented to uninfected target cells at a virological synapse

Experimental Evaluation of Publish/Subscribe-based Spatio-Temporal Contents Management on Geo-Centric Information Platform

Cross-domain data fusion is becoming a key driver to growth of the numerous and diverse applications in IoT era. Nevertheless, IoT data obtained by individual devices are blindly transmitted to cloud servers. We here focus on that the IoT data which are suitable for cross-domain data fusion, tend to be generated in the proximity, and thus propose a Geo-Centric Information Platform (GCIP) for the management of Spatio-Temporal Contents (STCs) generated through the cross-domain data fusion. GCIP enables to keep STCs near the users (at an edge server). In this paper, we practically examine the fundamental functions of the GCIP from two aspects: (1) Geo-location aware data collection and (2) Publish/Subscribe-based STC production. Furthermore, we implement a proof-of-concepts (PoC) of GCIP and conduct experiments on a real IPv6 network built on our campus network. In this experiment, we showed that multiple types of IoT data generated in the proximity can be collected on the edge server and then a STC can be produced by exploiting the collected IoT data. Moreover, we demonstrated that the Publish/Subscribe model has a potential to be effective for STC management.22nd International Conference on Network-Based Information Systems(NBiS 2019), September 5-7, 2019, Oita, Japa

Matching based content discovery method on Geo-Centric Information Platform

We have proposed a concept of new information platform, Geo-Centric information platform (GCIP), that enables IoT data fusion based on geolocation. GCIP produces new and dynamic contents by combining cross-domain data in each geographic area and provides them to users. In this environment, it is difficult to find appropriate contents requested by a user because the user cannot recognize what contents are created in each area beforehand. In this paper, we propose a content discovery method for GCIP. This method evaluates the relevancy between topics specified in user requests and topics representing IoT data used for creating contents, called matching, and presents the candidates for the desired contents based on the relevancy. Simulation results showed that appropriate contents can reliably be discovered in response to user’s request.12th International Workshop on Information Network Design (WIND-2020), in conjunction with 12th International Conference on Intelligent Networking and Collaborative Systems (INCoS-2020), August 31st - September 2nd, 2020, University of Victoria, Canada（新型コロナ感染拡大に伴い、現地開催中止

Rotationplasty for patients with osteosarcoma around the knee joint.

The results of rotationplasty for patients with osteosarcoma around the knee joint are presented. After an average observation period of 13.3 months, there has been no local recurrence or metastasis. The ankle joints (the new knee joints) of the patients were able to support their body weight with an average range of motion of 75 degrees. All patients could walk well without crutches and without risk of the giving way phenomenon. The average rate of the functional evaluation according to the re-modified system by Enneking was 84.5% (range, 80.0-86.7%). No patient had psychological trouble in accepting the shortened and rotated extremity. The results show that rotationplasty is a useful reconstructive method for the treatment of osteosarcoma around the knee joint.</p

Magnetic properties of surficial sediments in Lake Ogawara on the Pacific coast of northeastern Japan: spatial variability and correlation with brackish water stratification

To examine limnological conditions in Lake Ogawara on the Pacific coast of northwestern Japan, we investigated the magnetic properties of dredged bottom sediment originally collected from the lake in the summer of 2011. We used non-destructive methods to measure the low-field magnetic susceptibility shortl after sampling, and anhysteretic remanent magnetization (ARM) was assessed in 2012 and 2015. The ARM acquisition and demagnetization curves from littoral sites showed several patterns that reflect the provenance of the sediments. At water depths below 10 m, the magnetic susceptibility and ARM of greenish black mud with high organic content decreased considerably with the increase in water depth, but ARM increased slightly at water depths greater than 16 m. We also found that the magnetic concentrations of mud samples were reduced markedly during a period of storage for about 3 years. We attributed these reductions to diagenetic loss of magnetic minerals, which had been enhanced at deeper sites. It is possible that the ARM carriers in deeper areas were derived from authigenic formation of iron sulfide or from deposition of suspended matter in the hypolimnion water. We propose that the magnetic properties of surficial sediments are controlled by limnological stratification of the brackish lake water, thus possibly providing an analog for down-core variations of magnetic parameters associated with the modification of magnetic minerals during reductive diagenesis

Development of laser speckle blood flowmeter for evaluating the physiological function of skin

Objective: We developed and demonstrated laser speckle flowgraphy (LSFG) for two-dimensional (2D) skin blood flow (SBF) measurements to facilitate the noninvasive comparisons of SBF between individuals. Approach: By using morphing technology with a face mesh to compare SBF spatial distributions among individuals, we examined the practicability of SBF measurement with LSFG. Main results: (1) The uniformity of SBF measurement was demonstrated by examinations at different distances and angles for healthy subjects. (2) Mean blur rate (MBR)—a blood flow index of LSFG—exhibited significant correlation with the thermal diffusion method (TDM)—an established blood flow measurement method—suggesting that MBR is an effective index of SBF. (3) Blowout time, the half-width duration/duration of one cardiac cycle, exhibited significant negative correlation with age and positive correlation with stratum corneum hydration. Significance: These results suggest that LSFG is useful for evaluating SBF-related skin properties, and it has significant potential in medicine and cosmetology