Biosynthesis of the protoberberine alkaloid jatrorrhizine

Feeding experiments with distant single or doubly labelled precursors show that the methylene dioxy group of berberine is opened in the formation of jatrorrhizine

Nonequilibrium electron spin polarization in a double quantum dot. Lande mechanism

In moderately strong magnetic fields, the difference in Lande g-factors in each of the dots of a coupled double quantum dot device may induce oscillations between singlet and triplet states of the entangled electron pair and lead to a nonequilibrium electron spin polarization. We will show that this polarization may partially survive the rapid inhomogeneous decoherence due to random nuclear magnetic fields.Comment: New version contains figures. New title better reflects the content of the pape

S-adenosyl-L-methionine: (S)-scoulerine 9-O-methyltransferase, a highly stereo- and regio-specific enzyme in tetrahydroprotoberberine biosynthesis

Suspension cultures of Berberis species are useful sources for the detection and isolation of a new enzyme which transfers the methyl group from S-adenosyl-L-methionine specifically to the 9-position of the (S)-enantiomer of scoulerine, producing (S)-tetrahydrocolumbamine. The enzyme was enriched 27-fold; it is not particle bound, has a pH optimum of 8.9, a molecular weight of 63 000 and shows a high degree of substrate specificity

Strategies for Strengthening the Technical Workforce: A Review of International Evidence

Numerous countries suffer from a shortage of technicians and skilled workers, particularly in the STEM fields (science, technology, engineering, and mathematics), due to a mismatch between the skills and interests of the students graduating from or leaving the current education system and the needs of the labor market. Often, parents and students place a high priority on entering and completing university, and as a consequence, many students pursue academic education in secondary schools in order to gain entrance to university, only to find themselves entering the job market lacking the skills they need for employment and advancement. Further, in some countries, the vocational school system is not well-respected by the public and focuses heavily on preparation of youth for specific jobs in one firm rather than preparing them for careers within an industry as a whole. This literature review aims to synthesize the research evidence about the effectiveness of various strategies used by national governments, non-governmental organizations, technical schools, and industries to strengthen both the quality of the technical workforce, as well as the avenues through which individuals can access career and technical programming