The association between obesity and cognitive function in otherwise healthy premenopausal arab women

Objective. To examine the association between obesity and cognitive function in healthy premenopausal women. Methods. From a cohort of 220 women, 98 were randomly selected that provided complete data. Body composition was examined by dual-energy X-ray scan. All participants completed the Cambridge Neuropsychological Test Automated Battery (CANTAB) to assess cognitive performance in three domains: attention, memory, and planning executive function. The Reaction Time (RTI) test was used to assess motor and mental response speeds; the Stockings of Cambridge (SOC) test was used to assess planning executive function. For memory assessment, the Delayed Match to Sample (DMS), Pattern Recognition Memory (PRM), and Spatial Span (SSP) tests were used to assess forced choice recognition memory, visual pattern recognition memory, and working memory capacity, respectively. Results. 36 (36.7%) were morbidly obese, 22 (22.4%) obese, and 23 (23.5%) overweight. Performance on RTI and SOC planning ability were not associated with body mass index (BMI). DMS mean time to correct response, when stimulus is visible or immediately hidden (0 ms delay), was higher by 785 ± 302 ms (milliseconds) () and 587 ± 259 ms () in morbidly obese women compared to normal weight women. Memory span length was significantly lower in overweight (5.5 ± 1.3, ) and obese women (5.6 ± 1.6, ) compared to normal weight (6.7 ± 0.9). DEXA-assessed body fat (%) showed similar associations as BMI, and latency to correct response on DMS and PRM was positively correlated with percentage of body fat, but not with VO2 max. Conclusion. In otherwise healthy premenopausal women, obesity did not impact accuracy on cognitive tasks related to attention, memory, or planning executive function, but morbid obesity was associated with higher latency to correct response on memory-specific tasks and lower memory span length

Alterations in cognitive performance during passive hyperthermia are task dependent

The objectives of this study were to (1) assess the effect of passive heating upon attention and memory task performance, and (2) evaluate the effectiveness of the application of cold packs to the head on preserving these functions. Using a counterbalance design 16 subjects underwent three trials: a control (CON, 20°C, 40% rH), hot (HOT, 50°C, 50% rH) and hot with the head kept cool (HHC). In each condition, three attention tests and two memory tests were performed. Mean core, forehead and tympanic temperatures were all significantly higher (p< 0.05) during HOT (38.6° ±0.1°, 39.6° ±0.2° and 38.8°±0.1°C, respectively) and HHC (38°±0.2, 37.7°±0.3° and 37.7°C, respectively) than in CON (37.1°±0.6°, 33.3° ±0.2° and 35.9°±0.3°C, respectively). Results indicate that there was impairment in working memory with heat exposure (p < 0.05) without alteration in attentional processes. The regular application of cold packs only prevented the detrimental effect of hyperthermia on short-term memory. Our results show that impairments in cognitive function with passive hyperthermia and the beneficial effect of head cooling are task dependent and suggests that exposure to a hot environment is a competing variable to the cognitive processes

Less Is More—Cyclists-Triathlete’s 30 min Cycling Time-Trial Performance Is Impaired With Multiple Feedback Compared to a Single Feedback

Purpose: The purpose of this article was to (i) compare different modes of feedback (multiple vs. single) on 30 min cycling time-trial performance in non-cyclist’s and cyclists-triathletes, and (ii) investigate cyclists-triathlete’s information acquisition. Methods: 20 participants (10 non-cyclists, 10 cyclists-triathletes) performed two 30 min self-paced cycling time-trials (TT, ∼5–7 days apart) with either a single feedback (elapsed time) or multiple feedback (power output, elapsed distance, elapsed time, cadence, speed, and heart rate). Cyclists-triathlete’s information acquisition was also monitored during the multiple feedback trial via an eye tracker. Perceptual measurements of task motivation, ratings of perceived exertion (RPE) and affect were collected every 5 min. Performance variables (power output, cadence, distance, speed) and heart rate were recorded continuously. Results: Cyclists-triathletes average power output was greater compared to non-cyclists with both multiple feedback (227.99 ± 42.02 W; 137.27 ± 27.63 W; P 0.05). Whereas, cyclists-triathletes 30 min cycling time-trial performance was impaired with multiple feedback (227.99 ± 42.02 W) compared to single feedback (287.9 ± 60.07 W; p 0.05). Cyclists-triathlete’s primary and secondary objects of regard were power (64.95 s) and elapsed time (64.46 s). However, total glance time during multiple feedback decreased from the first 5 min (75.67 s) to the last 5 min (22.34 s). Conclusion: Cyclists-triathletes indoor 30 min cycling TT performance was impaired with multiple feedback compared to single feedback. Whereas non-cyclist’s performance did not differ between multiple and single feedback. Cyclists-triathletes glanced at power and time which corresponds with the wireless sensor networks they use during training. However, total glance time during multiple feedback decreased over time, and therefore, overloading athletes with feedback may decrease performance in cyclists-triathletes

Étude de l effet de l exposition à un environnement chaud sur les fonctions cognitives chez l homme

Une série de quatre études ont été réalisées dans une chambre environnementale dans des conditions chaudes (50C) et contrôles (24C) avec des durées d exposition variées. Les sujets ont réalisé une série de tests cognitifs simples et complexes. La température centrale (Tcore) et cutanée (Tskin) étaient enregistrées. Des mesures subjectives de confort et de sensation thermique étaient également recueillies. Lors de la quatrième étude un enregistrement EEG a été réalisé au niveau du lobe frontal. L hyperthermie ( 38.5C) n a pas eu d impact sur les tâches cognitives simples, alors que l impulsivité a augmentée dans les tâches nécessitant le maintien de l attention sur des durées prolongées. Une augmentation significative de la Tcore au delà de 38.7C était associée à une dégradation des fonctions cognitives complexes. De plus, des variations rapides et importantes de la Tskin indépendamment des changements de la Tcore suffisent à entraîner les mêmes conséquences sur les performances cognitives complexes. Les résultats suggèrent que les dégradations des fonctions cognitives complexes suite à l exposition a la chaleur proviennent de la charge cognitive imposée par le stress thermique résultant de l augmentation de la Tcore ou des variations allesthésiques de la Tskin; avec ces facteurs agissant comme variables concurrentes pour l accès à une capacité cognitive limitée. L augmentation de l amplitude des ondes Thêta et la diminution des ondes Alpha en HOT confirment que la tentative de réaffecter des ressources cognitives pour la réalisation des tâches complexes est inefficace étant donné la charge cognitive imposée par l hyperthermie passive.The aim of this thesis was to investigate the effects of exposure to a hot environment on cognitive performance. Methods: A series of four experiments were performed in an environmental chamber under both hot (HOT: 50C, 30% RH) and control (CON: 24C, 30% RH) conditions, with varied exposure times ranging from 15 minutes to 4h30min. Under different levels of thermal strain, subjects performed both simple and complex computerised cognitive tasks. Central (Tcore) and skin (Tskin) temperatures were continuously recorded. Subjective measures of thermal comfort and thermal sensation were also registered. During the forth study EEG was registered over the frontal lobe. Results: Hyperthermia had no impact upon reaction time and accuracy of responses of simple tasks, however, impulsivity increased during tasks that required sustaining attention over prolonged periods of time. Significant increases in Tcore beyond 38.7oC were associated with impaired complex cognitive task performance. In addition, rapid and substantial variations in Tskin ( 3oC in 15min of exposure to HOT), independent of any change in Tcore, had a similar detrimental effect upon complex cognitive tasks. The elevation in theta and alpha power showed a higher cognitive load in HOT during simple tasks but not during the complex tasks. Discussion & conclusion: The results suggest that these reductions in complex cognitive performance with heat exposure originate from an additional cognitive load imposed by the thermal strain associated to the increase in Tcore or the alliesthesial Tskin variations; with both these factors acting as competing variables to the limited cognitive processes. EEG recordings confirm that attempts to reallocate additional cognitive resources to perform complex tasks are unavailable given the load imposed by passive hyperthermia.ST DENIS-BU PARIS8 (930662101) / SudocSudocFranceF

Perception, Action, and Cognition of Football Referees in Extreme Temperatures: Impact on Decision Performance

Different professional domains require high levels of physical performance alongside fast and accurate decision-making. Construction workers, police officers, firefighters, elite sports men and women, the military and emergency medical professionals are often exposed to hostile environments with limited options for behavioral coping strategies. In this (mini) review we use football refereeing as an example to discuss the combined effect of intense physical activity and extreme temperatures on decision-making and suggest an explicative model. In professional football competitions can be played in temperatures ranging from -5°C in Norway to 30°C in Spain for example. Despite these conditions, the referee’s responsibility is to consistently apply the laws fairly and uniformly, and to ensure the rules are followed without waning or adversely influencing the competitiveness of the play. However, strenuous exercise in extreme environments imposes increased physiological and psychological stress that can affect decision-making. Therefore, the physical exertion required to follow the game and the thermal strain from the extreme temperatures may hinder the ability of referees to make fast and accurate decisions. Here, we review literature on the physical and cognitive requirements of football refereeing and how extreme temperatures may affect referees’ decisions. Research suggests that both hot and cold environments have a negative impact on decision-making but data specific to decision-making is still lacking. A theoretical model of decision-making under the constraint of intense physical activity and thermal stress is suggested. Future naturalistic studies are needed to validate this model and provide clear recommendations for mitigating strategies

Effect of Passive Hyperthermia on Working Memory Resources during Simple and Complex Cognitive Tasks

The aim of this study was to verify the hypothesis that hyperthermia represents a cognitive load limiting available resources for executing concurrent cognitive tasks. Electroencephalographic activity (EEG: alpha and theta power) was obtained in 10 hyperthermic participants in HOT (50°C, 50% RH) conditions and in a normothermic state in CON (25°C, 50% RH) conditions in counterbalanced order. In each trial, EEG was measured over the frontal lobe prior to task engagement (PRE) in each condition and during simple (One Touch Stockings of Cambridge, OTS-4) and complex (OTS-6) cognitive tasks. Core (39.5 ± 0.5 vs. 36.9 ± 0.2°C) and mean skin (39.06 ± 0.3 vs. 31.6 ± 0.6°C) temperatures were significantly higher in HOT than CON (p &lt; 0.005). Theta power significantly increased with task demand (p = 0.017, η2 = 0.36) and was significantly higher in HOT than CON (p = 0.041, η2 = 0.39). The difference between HOT and CON was large (η2 = 0.40) and significant (p = 0.036) PRE, large (η2 = 0.20) but not significant (p = 0.17) during OTS-4, and disappeared during OTS-6 (p = 0.87, η2 = 0.00). Those changes in theta power suggest that hyperthermia may act as an additional cognitive load. However, this load disappeared during OTS-6 together with an impaired performance, suggesting a potential saturation of the available resources

Effects of living and working in a hot environment on cognitive function in a quiet and temperature-controlled room: An oil and gas industry study

We investigate the effects of seasonal heat stress on cognitive function in outdoor workers. Thirty-nine workers from an oil and gas industry in the Middle-East volunteered for cognitive testing before (5.30 to 7.00 am) and after (3.30 to 5.00 pm) their daily work-shift in hot (August – average daily temperature: ~41°C) and temperate (January – average daily temperature: ~22°C) seasons. While physical activity was reduced in hot compared to temperate season (average normalized acceleration: 96 ± 33 vs. 112 ± 31 × 10−3 g; −12.5 ± 4.7%; P = 0.010), the average core temperature during the work-shift was higher in the hot season (37.4 ± 0.2 vs. 37.2 ± 0.2°C; P = 0.002). Peak core temperature was 38.0 ± 0.1°C and 37.8 ± 0.1°C in hot and temperate seasons, respectively. Cognitive performance did not differ between seasons for tests of recognition memory (P = 0.169), working memory (P = 0.797) and executive function (P = 0.145), independent of testing time. Whereas there was no significant main effect of testing time for tests of recognition memory (P = 0.503) and working memory (P = 0.849), the number of problems solved on the first choice for the executive function test was lower in the afternoon than the morning (−9.2 ± 5.3%; P = 0.039). There was no season × testing time interaction for any cognitive tests (P ≥ 0.145). In the absence of hyperthermia, living and working in a hot environment does not alter cognitive function in oil and gas industry workers tested in a quiet and temperature-controlled room, with reduced clothing encumbrance (relative to work). Conclusions should not be extrapolated to more stressful situations (i.e., thermal stressor present, pronounced dehydration, noise)

Heat acclimation has a protective effect on the central but not peripheral nervous system

This study aimed to clarify the pathway mediating hyperthermia-induced alterations in neural drive transmission and determine if heat acclimation protects voluntary muscle activation and cognitive function in hyperthermic humans. Electrically evoked potentials (H reflex and M wave), executive function (special planning and working memory), and maximal voluntary isometric contractions (120 s) were assessed in 14 participants in control conditions [CON, 24°C, 40% relative humidity (RH)] and in a hyperthermic state (HYP, 44-50°C, 50% RH) on consecutive days in a counterbalanced order. Thereafter, participants were passively heat acclimated for 11 days (1 h per day, 48-50°C, 50% RH) before repeating the initial assessments. Heat acclimation decreased rectal temperature in CON (-0.2°C, P 0.05), heat acclimation restored executive function, while protecting the ability to sustain voluntary activation and torque production during a prolonged contraction in hyperthermia (P < 0.05). Ultimately, heat acclimation induces beneficial central but not peripheral neural adaptations.NEW & NOTEWORTHY Heat acclimation restores planning accuracy and working memory in hyperthermic humans, together with the supraspinal capacity to sustain motor drive during a sustained maximal voluntary contraction. Electrically evoked potential data (M wave, H reflex) indicate that heat acclimation does not protect against hyperthermia-induced impairments in peripheral neural drive transmission. Heat acclimation induces beneficial central but not peripheral neural adaptations

Integrated multi-omics of the gut microbiome: assessing the beneficial effects of fermented foods to human health.

Evidence for health benefits of probiotic foods are increasing, with studies supporting the potential to prevent or even treat disease, including diabetes and obesity, suggesting fermented foods should be included as part of national dietary recommendations. Increasingly understood, is the potential for enhanced nutritional and functional properties due to transformation of substrates and formation of bioactive or bioavailable end-products. Many also contain living microorganisms, some of which are genetically similar to strains recognised as probiotics. Ingested bacteria can temporarily complement residential communities as part of a transient microbiome. Extent of integration is highly specie and strain dependent, and may vary depending on dietary context and baseline microbiota structure. Furthermore, delivery matrix may affect the health benefits