Does Injection of Lidocaine with 1/100000 Epinephrine Immediately before Lateral Osteotomy Reduce Post-Operative Periorbital Edema and Ecchymosis in Rhinoplasty?

Background: Postoperative periorbital edema and ecchymosis are common after rhinoplasty. We studied the effect of local injection of Lidocaine/Adrenaline immediately before osteotomy on prevention of post-operative periorbital edema and ecchymosis in rhinoplasty.Materials and Methods: Thirty healthy candidates for rhinoplasty were enrolled in the self-controlled clinical trial study. Lidocaine/Adrenaline solution injected randomly to one side just prior to the lateral osteotomy. The opposite side used as a control. The degree of edema/ecchymosis on both sides was compared on the 1st, 2nd and 7th day postoperatively.Results: Mean of severity of edema, 24 hours after operation was 3in both sides, (Mann-whitney U; p=0.829). Mean of severity of edema, 48 hours after operation was 2 in both sides (Mann-whitney U; p=0.867) and it was 1 in both sides 7 days after operation (Mann-whitney U; p=0.756).There was no significant difference between two sides. Mean of severity of ecchymosis, 24 hours after operation was 3 in both sides (Mann-whitney U; p=0.692). Mean of severity of ecchymosis, 48 hours after operation was 2 in both sides (Mann-whitney U; p=0.655) and it was 1 in both sides 7 days after operation (Mann-whitney U; p=0.873). There was no significant difference between two sides.Conclusion: local injection of Lidocaine/Adrenaline solution immediately before lateral osteotomy could not reduce postoperative edema and ecchymosis in rhinoplasty

The Relationship between Severe Hyperbilirubinemia and Abnormal Auditory Brainstem Response in children

Abstract:Background : Hyperbilirubinemia is one of the most common cause of congenital sensory neuronal hearing loss. These patients are screened by auditory brainstem response (ABR) test at bilirubin levels higher than 1% of gestational weight. Aim: to determine whether hyperbilirubinemia less than 1% of gestational weight could induce hearing loss and abnormal auditory brainstem response (ABR).Methods: in this case control study the outcome of ABR test in children younger than 3 years old with a history of term delivery and hyperbilirubinemia (bilirubin level less than 1% of gestational weight) were compared with the control group without hyperbilirubinemia matched for age and sex.Results: Mean ABR amplitude (wave I, V) were significantly prolonged in neonates with jaundice compared with controls (P0.6% gestational weight was 2.25 with 95% CI (1.44-3.89 and p=0.02).Conclusion: Our study showed a relevant association between bilirubin levels less than 20 mg/dl and abnormal ABR

The Relationship between Severe Hyperbilirubinemia and Abnormal Auditory Brainstem Response in children

Abstract:Background : Hyperbilirubinemia is one of the most common cause of congenital sensory neuronal hearing loss. These patients are screened by auditory brainstem response (ABR) test at bilirubin levels higher than 1% of gestational weight. Aim: to determine whether hyperbilirubinemia less than 1% of gestational weight could induce hearing loss and abnormal auditory brainstem response (ABR).Methods: in this case control study the outcome of ABR test in children younger than 3 years old with a history of term delivery and hyperbilirubinemia (bilirubin level less than 1% of gestational weight) were compared with the control group without hyperbilirubinemia matched for age and sex.Results: Mean ABR amplitude (wave I, V) were significantly prolonged in neonates with jaundice compared with controls (P0.6% gestational weight was 2.25 with 95% CI (1.44-3.89 and p=0.02).Conclusion: Our study showed a relevant association between bilirubin levels less than 20 mg/dl and abnormal ABR