Selection of the participants for the long-term evaluation analyses in the REDIA-prev1 cohort study.

<p>(Reunion Island, 2001–2011).</p

Maternal glycemic levels during pregnancy (mmol/l) related to offspring BMI (kg/m²) at 5–7 years by sex in group exposed to gestational diabetes mellitus.

<p>Maternal glycemic levels during pregnancy (mmol/l) related to offspring BMI (kg/m²) at 5–7 years by sex in group exposed to gestational diabetes mellitus.</p

Selection of infants for the OBEGEST cohort study (South Reunion Island, 2001–2010).

<p>GDM: gestational diabetes mellitus. GHSR: Groupe Hospitalier Sud-Réunion.</p

Gestational diabetes mellitus exposure and co-factors associated with offspring overweight (BMI ≥ IOTF-25) at 5–7 years by sex.

<p>Gestational diabetes mellitus exposure and co-factors associated with offspring overweight (BMI ≥ IOTF-25) at 5–7 years by sex.</p

Characteristics of study subjects by offspring sex and gestational diabetes mellitus exposure group.

<p>Characteristics of study subjects by offspring sex and gestational diabetes mellitus exposure group.</p

Baseline exercise tests at inclusion for LIPOXmax-Réunion randomized controlled trial participants.

<p>Data are means ± SD. FFM: Fat Free Mass. HR: Heart Rate. RER: Respiratory Exchange Ratio. W: Power. MFO: Maximal Fat Oxidation. p-values refer to comparisons between the three groups by one-way ANOVA or Kruskal-Wallis non parametric tests (*).</p><p>Baseline exercise tests at inclusion for LIPOXmax-Réunion randomized controlled trial participants.</p

Longitudinal evolution of metabolic characteristics (month-0, month-3 and month-5) in LIPOXmax-Réunion randomized controlled trial participants.

<p>Data are means ± SD for 103 subjects were followed-up at M0, M3 and M5). For MFO (mg/min/kg FFM), data are mean ± SD for n = 109 (subjects who participated at M0 and M5), because fat free mass DXA was measured only at M0 and at M5. M3: third month of intervention. M5: fifth month of intervention.HOMA-IR index: HOmeostasis Model Assessment estimated insulin resistance index. MFO: Maximal Fat Oxidation. FFM: Fat Free Mass. Repeated-measures ANOVA p-values represent the main effects of time (t), g (group) and the interaction effect (time *group).</p><p>Longitudinal evolution of metabolic characteristics (month-0, month-3 and month-5) in LIPOXmax-Réunion randomized controlled trial participants.</p

Post-hoc analysis (Repeated–measures ANOVA P values) for longitudinal evolution of metabolic characteristics (month-0, month-3 and month-5).

<p>HOMA-IR index: HOmeostasis Model Assessment estimated insulin resistance index. MFO: Maximal Fat Oxidation. FFM: Fat Free Mass. Repeated-measures ANOVA P values represent the main effects of time (t), g (group) and the interaction effect (time *group). Post-hoc analysis (G1 vs G2, G1 vs G3, G2 vs G3) was performed to compare groups two-by-two at p = 0.0167 significance level according to Bonferroni’s method.</p><p>Post-hoc analysis (Repeated–measures ANOVA P values) for longitudinal evolution of metabolic characteristics (month-0, month-3 and month-5).</p

Baseline inclusion characteristics for LIPOXmax-Réunion randomized controlled trial participants.

<p>^† Data are medians and interquartile range.</p><p>^‡ Data are medians and interquartile range. Otherwise, data are means ± SD or percentages. CMU: universal health coverage.</p><p>HOMA-IR index: Homeostasis Model Assessment estimated insulin resistance index. p-values refer to comparison between the three groups by one-way ANOVA or Kruskal-Wallis non parametric tests (*) for quantitative variables, and by Chi2 test or Fisher exact tests (*) for qualitative variables.</p><p>Baseline inclusion characteristics for LIPOXmax-Réunion randomized controlled trial participants.</p

Synoptic view of CoPanFlu protocol implementation.

<p>Green and violet lines represent the number of blood samples collected from the cohort, on inclusion (weeks 30–44) and at the end of the study (weeks 45–52) respectively (Y axis at the left: number of samples collected). Shaded area represents the profile of the epidemic wave in Reunion Island according to the local epidemiology surveillance unit (Y axis at the right: estimated number of symptomatic influenza cases occurring in the island); X axis: calendar weeks.</p