3 research outputs found
Etravirine induced severe hypersensitivity reaction and fulminant hepatitis: A case report and review of the literature.
We report the first published case of etravirine induced hypersensitivity reaction leading to fulminant hepatic failure in a 49-year-old female patient with Human Immunodefi ciency Virus. She presented with a life threatening rash and end stage organ damage requiring intensive care unit supportive care. Liver biopsy supported the diagnosis of drug-induced hypersensitivity. The patient recovered after withdrawal of etravirine and the use of systemic corticosteroids. The authors describe etravirine drug hypersensitivity as a clinically important reaction and that early recognition can improve survival
Additional file 1: of A phase 1 randomized, double-blind, placebo-controlled, crossover trial of DAS181 (FludaseÂŽ) in adult subjects with well-controlled asthma
Supplementary tables delineating additional pertinent study information, including inclusion and exclusion criteria, the schedule of study events, and the exploratory outcomes investigated. (DOCX 39 kb