23 research outputs found
Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England.
- Publication venue
- Vet Rec
- Publication date
- 11/08/2021
- Field of study
BACKGROUND: Bacterial lower respiratory tract infections (bLRTIs) are common and potentially life threatening in cats and dogs. Antibiotic treatment is often initiated before the diagnosis of bLRTI; therefore improved knowledge of the aetiology and antibiotic susceptibility patterns of these infections is essential to inform empiric antibiotic choices. METHODS: A retrospective study of microbiological, cytological results and their drug susceptibilities from lower respiratory samples (n = 1989) processed in a UK commercial laboratory between 2002 and 2012 was carried out. RESULTS: Thirty-nine per cent of feline samples and 50% of canine samples were positive for bacterial growth with most yielding a single organism (72 % and 69%, respectively). Bordetella bronchiseptica (20.2% from dogs and 2.3% from cats), Pasteurella spp. (23.2%, 31.8%), E. coli (16.2%, 13.6%) and Pseudomonas spp. (11.1%, 11.4%) were most frequently isolated from cytologically positive samples which contained intracellular bacteria (10%, 14%). Amoxycillin-clavulanate, cephalothin, cefovecin, oxytetracycline and trimethoprim/sulfamethoxazole showed modest in vitro activity against E. coli from dogs (approximately 70% susceptibility). Pseudomonas spp. were resistant to enrofloxacin (50%), ticarcillin (25%) and marbofloxacin (13%) but showed lower or zero resistance to aminoglycosides (approximately 7%) and ciprofloxacin (0%). Multi drug resistance (acquired resistance to three or more antimicrobial drug classes) was particularly common among E. coli isolates, with 23% from feline samples and 43% from canine samples. CONCLUSION: Resistance to certain first-choice antibiotics was detected in bLRTIs highlighting the need for continued monitoring and sound evidence to inform decision-making in the management of these infections
Search for the standard model Higgs boson in the diphoton decay channel with 4.9fb -1 of pp collision data at √s=7TeV with atlas
- Author
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- Åkesson TPA
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- Publication venue
- Publication date
- 01/01/2012
- Field of study
A search for the standard model Higgs boson is performed in the diphoton decay channel. The data used correspond to an integrated luminosity of 4.9 fb-1 collected with the ATLAS detector at the Large Hadron Collider in proton-proton collisions at a center-of-mass energy of √s=7 TeV. In the diphoton mass range 110–150 GeV, the largest excess with respect to the background-only hypothesis is observed at 126.5 GeV, with a local significance of 2.8 standard deviations. Taking the look-elsewhere effect into account in the range 110–150 GeV, this significance becomes 1.5 standard deviations. The standard model Higgs boson is excluded at 95% confidence level in the mass ranges of 113–115 GeV and 134.5–136 GeV
Search for the standard model Higgs boson in the diphoton decay channel with 4.9fb -1 of pp collision data at √s=7TeV with atlas
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- Wang JC
- Wang R
- Wang SM
- Warburton A
- Ward CP
- Warsinsky M
- Wasicki C
- Watkins PM
- Watson AT
- Watson IJ
- Watson MF
- Watts G
- Watts S
- Waugh AT
- Waugh BM
- Weber M
- Weber MS
- Weber P
- Weidberg AR
- Weigell P
- Weingarten J
- Weiser C
- Wellenstein H
- Wells PS
- Wenaus T
- Wendland D
- Wendler S
- Weng Z
- Wengler T
- Wenig S
- Wermes N
- Werner M
- Werner P
- Werth M
- Wessels M
- Wetter J
- Weydert C
- Whalen K
- Wheeler-Ellis SJ
- Whitaker SP
- White A
- White MJ
- Whitehead SR
- Whiteson D
- Whittington D
- Wicek F
- Wicke D
- Wickens FJ
- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik LAM
- Wijeratne PA
- Wildauer A
- Wildt MA
- Wilhelm I
- Wilkens HG
- Will JZ
- Williams E
- Williams HH
- Willis W
- Willocq S
- Wilson A
- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wolter MW
- Wolters H
- Wong WC
- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wozniak KW
- Wraight K
- Wright C
- Wright M
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wunstorf R
- Wynne BM
- Xella S
- Xiao M
- Xie S
- Xie Y
- Xu C
- Xu D
- Xu G
- Yabsley B
- Yacoob S
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamaoka J
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang UK
- Yang Y
- Yang Y
- Yang Z
- Yanush S
- Yao Y
- Yasu Y
- Ybeles Smit GV
- Ye J
- Ye S
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Young C
- Youssef S
- Yu D
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zaytsev A
- Zeitnitz C
- Zeller M
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenonos Z
- Zenz S
- Zerwas D
- Zevi Della Porta G
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Åkesson TPA
- Åsman B
- Publication venue
- Publication date
- 01/01/2012
- Field of study
A search for the standard model Higgs boson is performed in the diphoton decay channel. The data used correspond to an integrated luminosity of 4.9 fb-1 collected with the ATLAS detector at the Large Hadron Collider in proton-proton collisions at a center-of-mass energy of √s=7 TeV. In the diphoton mass range 110–150 GeV, the largest excess with respect to the background-only hypothesis is observed at 126.5 GeV, with a local significance of 2.8 standard deviations. Taking the look-elsewhere effect into account in the range 110–150 GeV, this significance becomes 1.5 standard deviations. The standard model Higgs boson is excluded at 95% confidence level in the mass ranges of 113–115 GeV and 134.5–136 GeV
Antibiotic resistance in bacteria associated with equine respiratory disease in the United Kingdom.
- Publication venue
- Vet Rec
- Publication date
- 22/05/2020
- Field of study
INTRODUCTION: Respiratory diseases account for the highest number of clinical problems in horses compared with other body systems. While microbiological culture and sensitivity testing is essential for certain cases, knowledge of the most likely bacterial agents and their susceptibilities is necessary to inform empirical antibiotic choices. METHODS: A retrospective study of microbiological and cytological results from upper and lower respiratory samples (n=615) processed in a commercial laboratory between 2002 and 2012 was carried out. A further study of lower respiratory samples from horses with clinical signs of lower respiratory disease from May to June 2012 was undertaken. RESULTS: Both studies revealed Streptococcus equi subspecies zooepidemicus, Pseudomonas aeruginosa, Pasteurella species, Escherichia coli and Bordetella bronchiseptica as the most frequently isolated species. S equi subspecies zooepidemicus and subspecies equi were susceptible to ceftiofur (100 per cent) and erythromycin (99 per cent). Resistance to penicillin (12.5 per cent of S equi subspecies equi from upper respiratory tract samples) and tetracycline (62.7 per cent) was also detected. Gram-negative isolates showed resistance to gentamicin, trimethoprim-sulfamethoxazole and tetracycline but susceptibility to enrofloxacin (except Pseudomonas species, where 46.2 per cent were resistant). Multiple drug resistance was detected in 1 per cent of isolates. CONCLUSION: Resistance to first-choice antibiotics in common equine respiratory tract bacteria was noted and warrants continued monitoring of their susceptibility profiles. This can provide information to clinicians about the best empirical antimicrobial choices against certain pathogenic bacteria and help guide antibiotic stewardship efforts to converse their efficacy
Minimally invasive myocardial revascularization
- Author
- Alexander E
- Alexander LF
- Alexander LF
- Benabid AL
- Berger MS
- Bisset K.
- Brown RA.
- Carter LP.
- Chandler WF
- Consensus statement on stereotactic radiosurgery: Quality improvement
- Dion JE
- Drake JM
- Friedman WA
- Fukushima T.
- Golfinos JG
- Goodman RR.
- Griffith HB
- Guglielmi G
- Guglielmi G
- Guthrie BL
- Heilbrun MP
- Higashida RT
- Jack CR
- Jellinek DA
- Kato AM
- Kelly PJ.
- Knake JE
- Lewis AI
- Loftus CM.
- Lownie S.
- Manwaring K
- Martin NA
- Mathis JM
- Mayer HM
- O'Brien PE.
- Ojemann G
- Olivier A
- Puce A
- Rajshekhar V.
- Roberts DW
- Roberts DW
- Rosenfeld JV
- Royal Australasian College of Surgeons
- Sandeman DR
- Satava RM.
- Steiner L
- Weinberg R.
- Wickham JEA.
- Wood CC
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2012
- Field of study
Influence of the Ionic Functionalities of Polyfluorene Derivatives as a Cathode Interfacial Layer on Inverted Polymer Solar Cells
- Author
- Bulliard X.
- Chen L.
- Dong-Yu Kim
- Duarte A.
- Feng X. L.
- Gong X.
- Guan X.
- Hau S. K.
- Helgesen M.
- Huang F.
- Huang F.
- Jea S.H.
- Jiang H.
- Jung G. H.
- Kang R.
- Koller J.
- Krienke H.
- Lee B.
- Lee K.
- Lee K.
- Lee T. -W.
- Lim K.-G.
- Na S. -I.
- Oh S. -H.
- Oh S. -H.
- Paramonov P. B.
- Park J.
- Po R.
- Rira Kang
- Schanze K. S.
- Seo J. H.
- Seo J. H.
- Servaites J. D.
- Seung-Hwan Oh
- Steim R.
- Sun K.
- Sun K.
- Søndergaard R.
- Wu L.
- Xie C.
- Yang T. B.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Effect of Pilopool on Forced Swimming Test in Mice
- Author
- Agarwal K. C
- Agusti K. T
- Coombes J. S.
- de-Mello M. A
- Dorchy H
- Eun-Hee Lee
- Fukushima M.
- Hatvani N
- Hou W. C.
- Huh K.
- Hyun-Ja Jeong
- Hyun-Jea Sung
- Hyun-Na Koo
- Hyung-Min Kim
- II-Kwang Kim
- Jae-Young Um
- Jeong H. J.
- Kim K. M.
- Kim M. S.
- Kumar G.
- Laires M. J.
- Lawson L. D
- Mizuno M
- Moriura T.
- Ng M. L.
- Nishimura K.
- Porsolt R. D.
- Seung-Heon Hong
- Sharma N. C.
- Shin H. Y.
- Yang J. S.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Dysregulated expression of ACTN4 contributes to endothelial cell injury via the activation of the p38-MAPK/p53 apoptosis pathway in preeclampsia
- Author
- AM ElKeeb
- B Sjoblom
- Chen Zhang
- CW Redman
- E Lomert
- EA Jaffe
- FH Li
- G Giannotti
- H Liu
- H Rao
- H Shao
- Hong Zou
- Hongbo Qi
- Huisheng Ge
- Hypertension in pregnancy
- J Goveia
- JEA Ribeiro
- Jianlin Zhao
- K Honda
- K Watanabe
- KJ Won
- KS Hsu
- L Marconcini
- LC Sanchez-Aranguren
- LJ Brennan
- NA Turner
- Q Gao
- QY Liu
- S Kim
- S Saito
- SW Walsh
- T Koizumi
- W Wang
- Wei Peng
- X Luo
- Y Hayashida
- Y Hiroi
- Y Matsuzawa
- Y Yuan
- Yubin Ding
- Yuxin Ran
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Structure-activity relationship studies of isoquinolinone type anticancer agent
- Author
- A. Noseda
- Bo-Gil Choi
- Byung-Ho Chung
- C. Dive
- C. Y. Watson
- Chong-Ock Lee
- E. J. Modest
- F. Uberall
- G. S. Poindexter
- Hyo Yi
- J. H. Hutchinson
- J. M. Berry
- Joon Suck Park
- Joon Yeol Lee
- L. V. Rubinstein
- M. J. Seewald
- P. G. Munder
- P. Skehan
- P. Workman
- S. Danhauser-Riedl
- S. H. Cheon
- S. H. Cheon
- S. H. Cheon
- Sang-Un Choi
- Seung Hoon Cheon
- V. C. Brunton
- W. C. Still
- W. E. Berdel
- W. J. Cho
- W. J. Houlihan
- W. J. Houlihan
- W. J. Houlihan
- W. J. Houlihan
- Won-Jea Cho
- You Na Lee
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Observations of Forsythia koreana methanol extract on mast cell-mediated allergic reactions in experimental models
- Author
- A. Alfonso
- A. Boe
- A. Chadi
- B. K. Shin
- B. Royer
- B. Royer
- C. Bronner
- C. M. Williams
- C. Tkaczyk
- D. D. Metcalfe
- D. H. Broide
- E. Sato
- E. V. Warbrick
- F. L. Pearce
- G. Camusi
- G. Krishnaswamy
- Goo Moon
- H. J. Jeong
- H. J. Na
- H. M. Kim
- H. Y. Shin
- Hyun-Ja Jeong
- Hyun-Jea Sung
- Hyun-Na Koo
- Hyung-Min Kim
- In-Young Choi
- J. Hoeck
- J. K. Shute
- Jae-Young Um
- Ji-Hyun Lee
- K. Tasaka
- L. J. Petersen
- M. Artuc
- M. C. Mousli
- M. C. Mousli
- M. Feldmann
- M. Hosoda
- M. S. Kim
- M. S. Kim
- M. Stassen
- N. Y. Kim
- Noh-Yil Myung
- P. A. Shore
- P. Bradding
- P. D. Moon
- P. Gosset
- Phil-Dong Moon
- R. W. Yurt
- Rae-Kil Park
- S. Hashimoto
- Se-Hee Han
- Seung-Heon Hong
- Su-Jin Kim
- Sung-Yum Seo
- T. Alonzi
- T. Jippo-Kanemoto
- T. Murrant
- T. Y. Shin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study