Detection of retinal vascular bifurcations by trainable v4-like filters

The detection of vascular bifurcations in retinal fundus images is important for finding signs of various cardiovascular diseases. We propose a novel method to detect such bifurcations. Our method is implemented in trainable filters that mimic the properties of shape-selective neurons in area V4 of visual cortex. Such a filter is configured by combining given channels of a bank of Gabor filters in an AND-gate-like operation. Their selection is determined by the automatic analysis of a bifurcation feature that is specified by the user from a training image. Consequently, the filter responds to the same and similar bifurcations. With only 25 filters we achieved a correct detection rate of 98.52% at a precision rate of 95.19% on a set of 40 binary fundus images, containing more than 5000 bifurcations. In principle, all vascular bifurcations can be detected if a sufficient number of filters are configured and used.peer-reviewe