15 research outputs found
Study of the effect of epidermal overhydration by occlusion, on the skin biomechanical behaviour assessed in vivo with the systems Cutometer® , Reviscometer® and CutiScan®
The Model of Population Transition in Vietnam in Relation to Europe and Asia: A Quantitative Approach
An integrated approach for analyzing air quality monitoring data: a case study in Hanoi, Vietnam
Polycyclic aromatic hydrocarbon (PAH) levels in environmental media potentially impacted by reused or stored creosote-treated railway ties
The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma
International audienceVascular endothelial (VE)-cadherin is an endothelial cell-specific protein responsible for endothelium integrity. Its adhesive properties are regulated by post-translational processing, such as tyrosine phosphorylation at site Y685 in its cytoplasmic domain, and cleavage of its extracellular domain (sVE). In hormone-refractory metastatic breast cancer, we recently demonstrated that sVE levels correlate to poor survival. In the present study, we determine whether kidney cancer therapies had an effect on VE-cadherin structural modifications and their clinical interest to monitor patient outcome