1,393 research outputs found
The dome: An unexpectedly simple failure of determinism
Newton's equations of motion tell us that a mass at rest at the apex of a dome with the shape specified here can spontaneously move. It has been suggested that this indeterminism should be discounted since it draws on an incomplete rendering of Newtonian physics, or it is "unphysical," or it employs illicit idealizations. I analyze and reject each of these reasons. Copyright 2008 by the Philosophy of Science Association. All rights reserved
Ignorance and indifference
The epistemic state of complete ignorance is not a probability distribution. In it, we assign the same, unique, ignorance degree of belief to any contingent outcome and each of its contingent, disjunctive parts. That this is the appropriate way to represent complete ignorance is established by two instruments, each individually strong enough to identify this state. They are the principle of indifference (PI) and the notion that ignorance is invariant under certain redescriptions of the outcome space, here developed into the 'principle of invariance of ignorance' (PII). Both instruments are so innocuous as almost to be platitudes. Yet the literature in probabilistic epistemology has misdiagnosed them as paradoxical or defective since they generate inconsistencies when conjoined with the assumption that an epistemic state must be a probability distribution. To underscore the need to drop this assumption, I express PII in its most defensible form as relating symmetric descriptions and show that paradoxes still arise if we assume the ignorance state to be a probability distribution. Copyright 2008 by the Philosophy of Science Association. All rights reserved
There are no universal rules for induction
In a material theory of induction, inductive inferences are warranted by facts that prevail locally. This approach, it is urged, is preferable to formal theories of induction in which the good inductive inferences are delineated as those conforming to universal schemas. An inductive inference problem concerning indeterministic, nonprobabilistic systems in physics is posed, and it is argued that Bayesians cannot responsibly analyze it, thereby demonstrating that the probability calculus is not the universal logic of induction. Copyright 2010 by the Philosophy of Science Association.All right reserved
Observationally Indistinguishable Spacetimes: A Challenge for Any Inductivist
Results on the observational indistinguishability of spacetimes demonstrate the impossibility of determining by deductive inference which is our spacetime, no matter how extensive a portion of the spacetime is observed. These results do not illustrate an underdetermination of theory by evidence, since they make no decision between competing theories and they make little contact with the inductive considerations that must ground such a decision. Rather, these results express a variety of indeterminism in which a specification of the observable past always fails to fix the remainder of a spacetime. This form of indeterminism is more troubling than the familiar indeterminism of quantum theory. The inductive inferences that can discriminate among the different spacetime extensions of the observed past are here called "opaque," which means that we cannot readily see the warrant that lies behind them
Why constructive relativity fails
Constructivists, such as Harvey Brown, urge that the geometries of Newtonian and special relativistic spacetimes result from the properties of matter. Whatever this may mean, it commits constructivists to the claim that these spacetime geometries can be inferred from the properties of matter without recourse to spatiotemporal presumptions or with few of them. I argue that the construction project only succeeds if constructivists antecedently presume the essential commitments of a realist conception of spacetime. These commitments can be avoided only by adopting an extreme form of operationalism
ID helix-loop-helix proteins as determinants of cell survival in B-cell chronic lymphocytic leukemia cells in vitro
Deductively Definable Logics of Induction
A broad class of inductive logics that includes the probability calculus is defined by the conditions that the inductive strengths [A{pipe}B] are defined fully in terms of deductive relations in preferred partitions and that they are asymptotically stable. Inductive independence is shown to be generic for propositions in such logics; a notion of a scale-free inductive logic is identified; and a limit theorem is derived. If the presence of preferred partitions is not presumed, no inductive logic is definable. This no-go result precludes many possible inductive logics, including versions of hypothetico-deductivism. © 2010 Springer Science+Business Media B.V
On thought experiments: Is there more to the argument?
Thought experiments in science are merely picturesque argumentation. I support this view in various ways, including the claim that it follows from the fact that thought experiments can err but can still be used reliably. The view is defended against alternatives proposed by my cosymposiasts. Copyright 2004 by the Philosophy of Science Association. All rights reserved
Absorbing and transferring risk: assessing the impact of a statewide high-risk-pregnancy telemedical program on VLBW maternal transports
BACKGROUND: Prior research has shown that resources have an impact on birth outcomes. In this paper we ask how combinations of telemedical and hospital-level resources impact transports of mothers expecting very low birth weight (VLBW) babies in Arkansas. METHODS: Using de-identified birth certificate data from the Arkansas Department of Health, data were gathered on transports of women carrying VLBW babies for two six-month periods: a period just before the start of ANGELS (12/02-05/03), a telemedical outreach program for high-risk pregnancies, and a period after the program had been running for six months (12/03-05/04). For each maternal transport, the following information was recorded: maternal race-ethnicity, maternal age, and the birth weight of the infant. Logistic regression was used to assess the relationship between the predictors (telemedicine, hospital level, maternal characteristics) and the probability of a transport. RESULTS: Having a telemedical site available increases the probability of a mother carrying a VLBW baby being transported to a level III facility either before or during birth. Having at least a level II nursery also increases the chance of a maternal transport. Where both level II nurseries and telemedical access are available, the odds of VLBW maternal transports are only modestly increased in comparison to the case where neither is present. At the individual level, Hispanic mothers were less likely to be transported than other mothers, and teenaged mothers were more likely to be transported than those 18 and over. A mother's being Black or being over 35 did not have an impact on the odds of being transported to a level III facility. CONCLUSION: Combinations of resources have an impact on physician decisions regarding VLBW transports and are interpretable in terms of the capacity to diagnose and absorb risk. We suggest a collegial review of transport patterns and birth outcomes from areas with different levels of resources as a vehicle for moving the entire system of care forward over time. With such an evidence-based review in place, the collegial relations among level III specialists and obstetricians from around the state can, over time, develop workable protocols for when and how level III facilities should be involved
Can ultrasound be used to stimulate nerve tissue?
BACKGROUND: The stimulation of nerve or cortical tissue by magnetic induction is a relatively new tool for the non-invasive study of the brain and nervous system. Transcranial magnetic stimulation (TMS), for example, has been used for the functional mapping of the motor cortex and may have potential for treating a variety of brain disorders. METHODS AND RESULTS: A new method of stimulating active tissue is proposed by propagating ultrasound in the presence of a magnetic field. Since tissue is conductive, particle motion created by an ultrasonic wave will induce an electric current density generated by Lorentz forces. An analytical derivation is given for the electric field distribution induced by a collimated ultrasonic beam. An example shows that peak electric fields of up to 8 V/m appear to be achievable at the upper range of diagnostic intensities. This field strength is about an order of magnitude lower than fields typically associated with TMS; however, the electric field gradients induced by ultrasound can be quite high (about 60 kV/m(2 )at 4 MHz), which theoretically play a more important role in activation than the field magnitude. The latter value is comparable to TMS-induced gradients. CONCLUSION: The proposed method could be used to locally stimulate active tissue by inducing an electric field in regions where the ultrasound is focused. Potential advantages of this method compared to TMS is that stimulation of cortical tissue could be highly localized as well as achieved at greater depths in the brain than is currently possible with TMS
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