Differentiating Non-Suicidal Self-Injury and Risky Drinking: a Role for Outcome Expectancies and Self-Efficacy Beliefs

© 2017 Society for Prevention ResearchSocial cognitive theory articulates a role for two key thought processes in governing volitional behaviour: outcome expectancies and self-efficacy expectancies. These cognitions are behaviour-specific, and should thus differentiate people who engage in one behaviour over another. This paper presents the results of a study applying social cognitive theory to explore how outcome expectancies and self-efficacy expectancies differentially relate to non-suicidal self-injury (NSSI) and risky alcohol use amongst a sample of young adults. A sample of 389 undergraduate students completed self-report questionnaires assessing their engagement in NSSI, alcohol consumption, their beliefs about the anticipated consequences of self-injury and alcohol consumption (outcome expectancies), and their belief in their ability to resist self-injury or risky drinking (resistance self-efficacy). Generally, people who self-injure rather than drink are characterised by a belief in the ability to resist drinking, coupled with stronger positive, and weaker negative, NSSI expectancies. People who self-injure are less likely to think alcohol reduces tension than people who do not self-injure. People who engaged in both NSSI and risky drinking report more anxiety than participants who engaged only in risky drinking and lowered ability to resist self-injury. Overall, the findings suggest that a unique combination of beliefs differentially predict NSSI and drinking. The pattern of results suggests potential avenues for future research to delineate why people engage in one behaviour rather than another and to inform future prevention and early intervention initiatives

Drosophila melanogaster: A Valuable Genetic Model Organism to Elucidate the Biology of Retinitis Pigmentosa.

Retinitis pigmentosa (RP) is a complex inherited disease. It is associated with mutations in a wide variety of genes with many different functions. These mutations impact the integrity of rod photoreceptors and ultimately result in the progressive degeneration of rods and cone photoreceptors in the retina, leading to complete blindness. A hallmark of this disease is the variable degree to which symptoms are manifest in patients. This is indicative of the influence of the environment, and/or of the distinct genetic makeup of the individual.The fruit fly, Drosophila melanogaster, has effectively proven to be a great model system to better understand interconnected genetic networks. Unraveling genetic interactions and thereby different cellular processes is relatively easy because more than a century of research on flies has enabled the creation of sophisticated genetic tools to perturb gene function. A remarkable conservation of disease genes across evolution and the similarity of the general organization of the fly and vertebrate photoreceptor cell had prompted research on fly retinal degeneration. To date six fly models for RP, including RP4, RP11, RP12, RP14, RP25, and RP26, have been established, and have provided useful information on RP disease biology. In this chapter, an outline of approaches and experimental specifications are described to enable utilizing or developing new fly models of RP